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Functional development of preterm children born from singleton and multiple pregnancies: Preliminary study


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The results of the Munich Functional Developmental Diagnostics for singletons, twins and triplets

Sphere of development pregnancy n q2 (q1-q3) 50%# p* q2 (q1-q3) 95%## p*
Walking age singleton 10 1.08 (0.99-1.13) 0.24 0.83 (0.81-0.92) 0.28
twin 12 1.05 (1.01-1.08) 0.85 (0.83-0.88)
triplet 21 1.01 (0.96-1.08) 0.81 (0.77-0.84)
Manual skillfulness age singleton 10 1.02 (0.94-1.13) 0.67 0.76 (0.7-0.85) 0.54
twin 12 1 (0.94-1.04) 0.76 (0.72-0.76)
triplet 21 1.01 (0.93-1.04) 0.75 (0.69-0.76)
Perception age singleton 10 1.11 (1.07-1.15) 0.26 0.89 (0.84-0.92) 0.14
twin 12 1.1 (1.08-1.12) 0.87 (0.82- 0.91)
triplet 21 1.04 (1-1.13) 0.81 (0.79-0.91)
Active speech age singleton 10 1.23 (1.16-1.31) 0.78 0.88 (0.83-0.97) 0.69
twin 12 1.15 (1.09-1.24) 0.81 (0.79-0.91)
triplet 21 1.18 (1.08-1.3) 0.84 (0.81-0.89)
Speech understanding age singleton 10 1.1 (1.04-1.14) 0.62 0.86 (0.82-0.88) 0.91
twin 12 1.13 (1.05-1.19) 0.84 (0.81-0.88)
triplet 21 1.12 (1.08-1.3) 0.86 (0.81-0.98)
Social development age singleton 10 1.15 (1.03-1.28) 0.82 0.81 (0.76-1) 0.81
twin 12 1.11 (1.08-1.26) 0.88 (0.8-0.98)
triplet 21 1.13 (1.1-1.3) 0.96 (0.81-0.96)
Independence age singleton 10 1.13 (1.07-1.18) 0.29 0.79 (0.76-0.83) 0.63
twin 12 1.11 (1-1.13) 0.79 (0.73-0.85)
triplet 21 1.08 (1.04-1.12) 0.77 (0.76-0.81)

Birth parameters of the examined group

Variable Group p*
1 (N = 10) 2 (N = 12) 3 (N = 21)
Weight [g], mean (SD) 1919 (481.33) 2004.17 (256.67) 1669.38 (279.38) 0.017
Body length [cm], mean (SD) 45.9 (3.57) 47.25 (3.55) 43.38 (3.47) 0.011
Head circumference [cm], mean (SD) 30.5 (2.32) 31.08 (1.73) 30.14 (1.68) 0.384
Chest circumference [cm], mean (SD) 27 (2.36) 27.08 (1.73) 26.14 (2.15) 0.376
Apgar scale 1’, median (Q1–Q3) 8 (6.5-9.75) 7.5 (7-10) 7 (6-8) 0.374
Apgar scale 5’, median (Q1–Q3) 8.5 (8-9.75) 9 (7-10) 8 (7-8) 0.052

Characteristics of the study group

Variable n (%) Category Group 1 (N=10) Group 2 (N=12) Group 3 (N=21) p#
sex girlboy 4 (40)6 (60) 4 (33.33)8 (66.67) 10 (47.62)11 (52.38) 0.719
place of residence villagecity up to 100city with over 100 4 (40)2 (20)4 (40) 4 (33.33)4 (33.33)4 (33.33) 9 (42.86)6 (28.57)6 (28.57) 0.938
mother’s education basicmediumhigher 2 (20)3 (30)5 (50) 0 (0)2 (16.67)10 (83.33) 0 (0)9 (42.86)12 (57.14) 0.052
father’s education basicmediumhigher 2 (20)4 (40)4 (40) 0 (0)4 (33.33)8 (66.67) 0 (0)6 (28.57)15 (71.,43) 0.092
economic situation weaksufficientvery good 1 (10)8 (80)1 (10) 0 (0)6 (50)6 (50) 3 (14.29)9 (42.86)9 (42.86) 0.187
family status single parentfull family 0 (0)10 (100) 2 (16.67)10 (83.33) 0 (0)21 (100) 0.067
number of siblings 0123 5 (50)2 (20)3 (30)0 (0) 0 (0)10 (83.33)0 (0)2 (16.67) 0 (0)0 (0)15 (71.43)6 (28.57) 0.000
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