The role of prenatal cardiology and the organization of perinatal cardiological centers in early diagnostics and early therapeutic procedures in fetuses and newborns with cardiac malformations and circulatory disturbances was discussed on the basis of the literature and own experience. The possibilities of an early perinatal diagnosis and early therapeutic approaches to cardiac defects were presented. It was stressed that there is a necessity to broaden the educational aims in these areas and in the near future to prepare multidisciplinary teams working together in specialist centers.