This work is licensed under the Creative Commons Attribution 4.0 International License.
Lederberg J, McCray AT. ‘Ome Sweet’ Omics – a genealogical treasury of words. Scientist. 2001;15:8.LederbergJMcCrayAT‘Ome Sweet’ Omics – a genealogical treasury of words2001158Search in Google Scholar
Turnbaugh PJ, Ley RE, Hamady M, Fraser-Liggett CM, Knight R, Gordon JI. The human microbiome project. Nature. 2007;449: 804-810.TurnbaughPJLeyREHamadyMFraser-LiggettCMKnightRGordonJIThe human microbiome project200744980481010.1038/nature06244Search in Google Scholar
The NIH HMP Working Group, The NIH Human Microbiome Project. Genome Research. 2009;19:317-2323.The NIH HMP Working Group, The NIH Human Microbiome Project200919317232310.1101/gr.096651.109Search in Google Scholar
Handelsman J. Metagenomics: application of genomics to uncultured microorganisms. Microbiol Mol Biol Rev. 2004;68:669-685.HandelsmanJMetagenomics: application of genomics to uncultured microorganisms20046866968510.1128/MMBR.68.4.669-685.2004Search in Google Scholar
Gill SR, Pop M,Deboy RT i wsp. Metagenomic Analysis of Human Distal Gut Microbiome. Science. 2006;312:1355-1359.GillSRPopMDeboyRTi wspMetagenomic Analysis of Human Distal Gut Microbiome20063121355135910.1126/science.1124234Search in Google Scholar
Zhu B, Wang X, Li L. Human gut microbiome: the second genome of body. Protein Cell. 2010;1:718-725.ZhuBWangXLiLHuman gut microbiome: the second genome of body2010171872510.1007/s13238-010-0093-zSearch in Google Scholar
Ludwig W, Schleifer KH. Bacterial phylogeny based on 16S and 23S rRNA sequence analysis. FEMS Microbiol Rev. 1994;15: 55-173.LudwigWSchleiferKHBacterial phylogeny based on 16S and 23S rRNA sequence analysis1994155517310.1111/j.1574-6976.1994.tb00132.xSearch in Google Scholar
Macfarlane S, Macfarlane GT. Bacterial diversity in the human gut. Adv Appl Microbiol.2004;54: 261-289.MacfarlaneSMacfarlaneGTBacterial diversity in the human gut20045426128910.1016/S0065-2164(04)54010-8Search in Google Scholar
Eckburg PB, Bik EM, Bernstein CN, Purdom E, Dethlefsen L, Sargent M, Gill SR, Nelson KE, Relman DA. Diversity of the human intestinal microbial ( ora. Science.2005; 308:1635-1638.EckburgPBBikEMBernsteinCNPurdomEDethlefsenLSargentMGillSRNelsonKERelmanDADiversity of the human intestinal microbial ( ora20053081635163810.1126/science.1110591139535715831718Search in Google Scholar
Frank DN, St Amand AL, Feldman RA, Boedeker EC, Harpaz N, Pace NR. Molecular-phylogenetic characterization of microbial community imbalances in human in( ammatory bowel diseases. Proc Natl Acad Sci. USA, 2007;04:13780-13785.FrankDNStAmand ALFeldmanRABoedekerECHarpazNPaceNR.Molecular-phylogenetic characterization of microbial community imbalances in human in( ammatory bowel diseases200704137801378510.1073/pnas.0706625104195945917699621Search in Google Scholar
Aagaard K, Ma J, Antony KM i wsp. The placenta harbors a unique microbiome. Sci Transl Med. 2014;6:237.AagaardKMaJAntonyKM i wspThe placenta harbors a unique microbiome2014623710.1126/scitranslmed.3008599492921724848255Search in Google Scholar
Mueller NT, Bakacs E, Combellck et.al. The infant microbiome development: mom matters. Trends Mol Med. 2015;21(2):109-117.MuellerNTBakacsECombellck et.alThe infant microbiome development: mom matters201521210911710.1016/j.molmed.2014.12.002446466525578246Search in Google Scholar
Collado MC, Rautava S, Aakko I, wsp. Human gut colonisation may be initiated in utero by distinct microbial communities in the placenta and amniotic fluid. Sci Rep. 2016:6:23129.ColladoMCRautavaSAakkoIwspHuman gut colonisation may be initiated in utero by distinct microbial communities in the placenta and amniotic fluid201662312910.1038/srep23129480238427001291Search in Google Scholar
The Gut Microbiome and Childhood Obesity: Connecting the Dots An interview with Noel Theodore Mueller, PhD, MPH, CHILDHOOD OBESITY, June 2015 j Volume 11, Number 3.June2015j Volume 11Number 310.1089/chi.2015.29000.nm691379726034811Search in Google Scholar
Palmer C, Bik EM, DiGiulio DB, Relman DA, Brown PO. Development of the human infant intestinal microbiota. PLoS Biol.2007; 5: e177.PalmerCBikEMDiGiulioDBRelmanDABrownPODevelopment of the human infant intestinal microbiota20075e17710.1371/journal.pbio.0050177189618717594176Search in Google Scholar
Mariat D, Firmesse O, Levenez F, Guimarăes V, Sokol H, Doré J, Corthier G, Furet JP. The Firmicutes/Bacteroidetes ratio of the human microbiota changes with age. BMC Micro- biol.2009; 9:123.MariatDFirmesseOLevenezFGuimarăesVSokolHDoréJCorthierGFuretJPThe Firmicutes/Bacteroidetes ratio of the human microbiota changes with age2009912310.1186/1471-2180-9-123270227419508720Search in Google Scholar
Salimen S, Gibson GR, McCartney AL. In( uence of mode of delivery on gut microbiota in seven year old children. Gut. 2004;53:1388-1389.SalimenSGibsonGRMcCartneyALIn( uence of mode of delivery on gut microbiota in seven year old children2004531388138910.1136/gut.2004.041640177421115306608Search in Google Scholar
Mueller NT, et al. Prenatal exposure to antibiotics, Cesarean section and risk of childhood obesity. Int J Obes (Lond). Int J Obes (Lond). 2015;39(4):665-670.MuellerNTet alPrenatal exposure to antibiotics, Cesarean section and risk of childhood obesity201539466567010.1038/ijo.2014.180439047825298276Search in Google Scholar
Scheepers L, Penders J, Mbakwa C i wsp. The intestinal microbiota composition and weight development in children:the KOALA Birth Cohort Study. Int J Obes.2015;39:16-25.ScheepersLPendersJMbakwaC i wsp.The intestinal microbiota composition and weight development in children:the KOALA Birth Cohort Study201539162510.1038/ijo.2014.17825298274Search in Google Scholar
Harris K, Kassis A, Major G, Chou CJ. Is the gut microbiota a new factor contributing to obesity and its metabolic disorders? J Obes.2012;2012: 879151.HarrisKKassisAMajorGChouCJIs the gut microbiota a new factor contributing to obesity and its metabolic disorders?2012201287915110.1155/2012/879151327044022315672Search in Google Scholar
De Filippo C, Cavalieri D, Di Paola M, Ramazzotti M i wsp. Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa. Proc Natl Acad Sci. USA, 2010;107:14691-14696.DeFilippo CCavalieriDDiPaola MRamazzottiM i wsp.Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa2010107146911469610.1073/pnas.1005963107293042620679230Search in Google Scholar
Ley RE, Bäckhed F, Turnbaugh P, Lozupone CA, Knight RD, Gordon JI. Obesity alters gut microbial ecology. Proc Natl Acad.Sci. USA, 2005;102:11070-11075.LeyREBäckhedFTurnbaughPLozuponeCAKnightRDGordonJIObesity alters gut microbial ecology2005102110701107510.1073/pnas.0504978102117691016033867Search in Google Scholar
Ley RE, Peterson DA, Gordon JI. Ecological and evolutionary forces shaping microbial diversity in the human intestine. Cell. 2006;124:837-848.LeyREPetersonDAGordonJIEcological and evolutionary forces shaping microbial diversity in the human intestine200612483784810.1016/j.cell.2006.02.01716497592Search in Google Scholar
Stewart JA, Chadwick VS, Murray A. Investigations into the influence of host genetics on the predominant eubacteria in the faecal micro( ora of children. J Med Microbiol. 2005;54:1239-1242.StewartJAChadwickVSMurrayAInvestigations into the influence of host genetics on the predominant eubacteria in the faecal micro( ora of children2005541239124210.1099/jmm.0.46189-016278440Search in Google Scholar
Turnbaugh PJ, Ridaura VK, Faith JJ, Rey FE, Knight R, Gordon JI. The effect of diet on the human gut microbiome: a meta- genomic analysis in humanized gnotobiotic mice. Sci Transl Med, 2009;1:6ra14.TurnbaughPJRidauraVKFaithJJReyFEKnightRGordonJIThe effect of diet on the human gut microbiome: a meta- genomic analysis in humanized gnotobiotic mice200916ra1410.1126/scitranslmed.3000322289452520368178Search in Google Scholar
Turnbaugh PJ at al. An obesity-associated gut microbiome with increased capacity for energy harvest. Nature 2006;444:1027-1031.TurnbaughPJat alAn obesity-associated gut microbiome with increased capacity for energy harvest20064441027103110.1038/nature0541417183312Search in Google Scholar
Turnbaugh PJ, Bäckhed F, Fulton L, Gordon JI. Diet-induced obesity is linked to marked but reversible alterations in the mouse distal Gut microbiome. Cell Host Microbe. 2008;3:213-223.TurnbaughPJBäckhedFFultonLGordonJIDiet-induced obesity is linked to marked but reversible alterations in the mouse distal Gut microbiome2008321322310.1016/j.chom.2008.02.015368778318407065Search in Google Scholar
Bäckhed F, Manchester JK, Semenkovich CF, Gordon JI. Mechanisms underlying the resistance to diet-induced obesity in germ-free mice. Proc Natl Acad Sci. USA, 2007;104:979-984.BäckhedFManchesterJKSemenkovichCFGordonJI.Mechanisms underlying the resistance to diet-induced obesity in germ-free mice200710497998410.1073/pnas.0605374104176476217210919Search in Google Scholar
Ley RE, Turnbaugh PJ, Klein S, Gordon JI. Microbial ecology: human gut microbes associated with obesity. Nature. 2006;444:1022-1023.LeyRETurnbaughPJKleinSGordonJIMicrobial ecology: human gut microbes associated with obesity20064441022102310.1038/4441022a17183309Search in Google Scholar
Burcelin R, Serino M, Chabo C, Blasco-Baque V, Amar J. Gut microbiota and diabetes: from pathogenesis to therapeutic perspective. Acta Diabetol. 2011;48:257-273.BurcelinRSerinoMChaboCBlasco-BaqueVAmarJGut microbiota and diabetes: from pathogenesis to therapeutic perspective20114825727310.1007/s00592-011-0333-6322422621964884Search in Google Scholar
Stappenbeck TS, Hooper LV, Gordon JI. Developmental regulation of intestinal angiogenesis by indigenous microbes via Paneth cells. Proc Natl Acad Sci. USA. 2002;99:15451-15455.StappenbeckTSHooperLVGordonJIDevelopmental regulation of intestinal angiogenesis by indigenous microbes via Paneth cells200299154511545510.1073/pnas.20260429913773712432102Search in Google Scholar
Schwiertz A, Taras D, Schäfer K, Beijer S, Bos NA, Donus C, Hardt PD. Microbiota and SCFA in lean and overweight healthy subjects. Obesity. 2010;18:190-195.SchwiertzATarasDSchäferKBeijerSBosNADonusCHardtPDMicrobiota and SCFA in lean and overweight healthy subjects20101819019510.1038/oby.2009.16719498350Search in Google Scholar
Nicholson JK, Holmes E, Kinross J, Burcelin R, Gibson G, Jia W, Pettersson S. Host-gut microbiota metabolic interactions. Science. 2012;336:1262-1267.NicholsonJKHolmesEKinrossJBurcelinRGibsonGJiaWPetterssonSHost-gut microbiota metabolic interactions20123361262126710.1126/science.122381322674330Search in Google Scholar
Gao Z, Yin J, Zhang J, Ward RE, Martin RJ, Lefevre M, Cefalu WT, Ye J. Butyrate improves insulin sensitivity and increases energy expenditure in mice. Diabetes. 2009;58:1509-1517.GaoZYinJZhangJWardREMartinRJLefevreMCefaluWTYeJButyrate improves insulin sensitivity and increases energy expenditure in mice2009581509151710.2337/db08-1637269987119366864Search in Google Scholar
Kootte RS, Vrieze A, Holleman F, Dallinga-Thie GM, Zoetendal EG, de Vos WM, Groen AK, Hoekstra JB, Stroes ES, Nieuwdorp M. The therapeutic potential of manipulating gut microbiota in obesity and type 2 diabetes mellitus. Diabetes Obes Metab.2012;14:112-120.KootteRSVriezeAHollemanFDallinga-Thie GMZoetendalEGdeVos WMGroenAKHoekstraJBStroesESNieuwdorpM.The therapeutic potential of manipulating gut microbiota in obesity and type 2 diabetes mellitus20121411212010.1111/j.1463-1326.2011.01483.x21812894Search in Google Scholar
Bäckhed F, Ding H, Wang T, Hooper LV, Koh GY, Nagy A, Semenkovich CF, Gordon JI. The gut microbiota as an environmen- tal factor that regulates fat storage. Proc Natl Acad Sci. USA. 2004;101:15718-15723.BäckhedFDingHWangTHooperLVKohGYNagyASemenkovichCFGordonJIThe gut microbiota as an environmen- tal factor that regulates fat storage2004101157181572310.1073/pnas.040707610152421915505215Search in Google Scholar
Swann JR, Want EJ, Geier FM, Spagou K, Wilson ID, Sidaway JE, Nicholson JK, Holmes E. Systemic gut microbial modulation of bile acid metabolism in host tissue compartments. Proc Natl Acad Sci. USA. 2011;108(Suppl.1):4523-4530.SwannJRWantEJGeierFMSpagouKWilsonIDSidawayJENicholsonJKHolmesESystemic gut microbial modulation of bile acid metabolism in host tissue compartments2011108Suppl.14523453010.1073/pnas.1006734107306358420837534Search in Google Scholar
Q omas C, Gioiello A, Noriega L, Strehle A, Oury J, Rizzo G, Macchiarulo A, Yamamoto H, Mataki C, Pruzanski M, Pellicciari R, Auwerx J, Schoonjans K. TGR5- mediated bile acid sensing controls glucose homeostasis. Cell Metab. 2009;10:167-177.Qomas CGioielloANoriegaLStrehleAOuryJRizzoGMacchiaruloAYamamotoHMatakiCPruzanskiMPellicciariRAuwerxJSchoonjansK.TGR5- mediated bile acid sensing controls glucose homeostasis20091016717710.1016/j.cmet.2009.08.001273965219723493Search in Google Scholar
Barcenilla A, Pryde SE, Martin JC, Duncan SH, Stewart CS, Henderson C, Flint HJ. Phylogenetic relationships of butyrate- producing bacteria from the human gut. Appl. Environ. Microbiol. 2000;66:1654-1661.BarcenillaAPrydeSEMartinJCDuncanSHStewartCSHendersonCFlintHJPhylogenetic relationships of butyrate- producing bacteria from the human gut2000661654166110.1128/AEM.66.4.1654-1661.20009203710742256Search in Google Scholar
Duncan SH, Belenguer A, Holtrop G, Johnstone AM, Flint HJ, Lobley GE. Reduced dietary intake of carbohydrates by obese subjects results in decreased concentrations of butyrate and butyrate-producing bacteria in feces. Appl Environ Microbiol. 2007;73:1073-1078.DuncanSHBelenguerAHoltropGJohnstoneAMFlintHJLobleyGEReduced dietary intake of carbohydrates by obese subjects results in decreased concentrations of butyrate and butyrate-producing bacteria in feces2007731073107810.1128/AEM.02340-06182866217189447Search in Google Scholar