<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>The infectious agents may be the etiological factor of up to 15–20% of cancers. In stomach cancer, attention is paid to <italic>Helicobacter pylori</italic> and Epstein-Barr virus, both of which cause gastritis and can lead to tumor development. In co-infection, the inflammatory process is much more intense. We assessed the seroprevalence towards <italic>H. pylori</italic> and EBV in 32 patients with diagnosed gastric cancer. <italic>H. pylori</italic> antibodies were found in 69% patients, and anti-EBV – in all of them. The study confirmed that co-infection of <italic>H. pylori</italic> and EBV seems to be important in etiopathology of gastric cancer.</p>
<p>
<fig id="j_pjm-2022-004_fig_003" position="anchor" fig-type="figure">
<graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="graphic/j_pjm-2022-004_fig_003.jpg"></graphic>
</fig>
</p>
</abstract>

The infectious agents may be the etiological factor of up to 15–20% of cancers. In stomach cancer, attention is paid to Helicobacter pylori and Epstein-Barr virus, both of which cause gastritis and can lead to tumor development. In co-infection, the inflammatory process is much more intense. We assessed the seroprevalence towards H. pylori and EBV in 32 patients with diagnosed gastric cancer. H. pylori antibodies were found in 69% patients, and anti-EBV – in all of them. The study confirmed that co-infection of H. pylori and EBV seems to be important in etiopathology of gastric cancer.

<italic>Helicobacter pylori</italic> and Epstein-Barr Virus Co-Infection in Polish Patients with Gastric Cancer – A Pilot Study

Department of Biomedicine and Genetics, Chair of Biology and Medical Microbiology

Department of Microbiology and Laboratory Medical Immunology, Chair of Biology and Medical Microbiology

Central Clinical Hospital of the Medical University of Lodz

Polish Journal of Microbiology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

 and Epstein-Barr Virus Co-Infection in Polish Patients with Gastric Cancer – A Pilot Study

The infectious agents may be the etiological factor of up to 15–20% of cancers. In stomach cancer, attention is paid to Helicobacter pylori and Epstein-Barr...

	TNM classification
	T1	T2	T3	N0	T4	N1	N3	N2	M0
n	7	3	18	4	11	5	7	9	32
AJCC staging
	stage I (localized cancer)			stage II (locally advanced cancer, early stages)			stage III (locally advanced cancer, late stages)
n	8			9			15

Helicobacter pylori and Epstein-Barr Virus Co-Infection in Polish Patients with Gastric Cancer – A Pilot Study

Article Category: Short Communication

Publicado en línea: 27 feb 2022

Páginas: 123 - 129

Recibido: 30 oct 2021

Aceptado: 03 ene 2022

DOI: https://doi.org/10.33073/pjm-2022-004

Palabras clave
co-infection, EBV, gastric cancer, prevalence, infection agents in cancer

© 2022 Magdalena Dzikowiec et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Fig. 1

Fig. 2

The number of tumor specimens (n) classified according to TNM classification and AJCC staging.

Helicobacter pylori and Epstein-Barr Virus Co-Infection in Polish Patients with Gastric Cancer – A Pilot Study

Article Category: Short Communication

Publicado en línea: 27 feb 2022

Páginas: 123 - 129

Recibido: 30 oct 2021

Aceptado: 03 ene 2022

DOI: https://doi.org/10.33073/pjm-2022-004

Palabras claveco-infection, EBV, gastric cancer, prevalence, infection agents in cancer

© 2022 Magdalena Dzikowiec et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Fig. 1

Fig. 2

The number of tumor specimens (n) classified according to TNM classification and AJCC staging.

Palabras clave
co-infection, EBV, gastric cancer, prevalence, infection agents in cancer