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The Resurgence of Measles Infection and its Associated Complications in Early Childhood at a Tertiary Care Hospital in Peshawar, Pakistan


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Fig. 1.

The overall distribution of anti-measles antibody (IgM) in patients’ sera (n = 100).
The overall distribution of anti-measles antibody (IgM) in patients’ sera (n = 100).

Fig. 2.

Gender distribution of measles complications (Percentage).
Gender distribution of measles complications (Percentage).

Fig. 3.

Number of confirmed measles cases from 2006 to 2019 in Pakistan (WHO 2019; updates).
Number of confirmed measles cases from 2006 to 2019 in Pakistan (WHO 2019; updates).

Fig. 4.

Distribution of measles complications among measles-vaccinated and unvaccinated children.
Distribution of measles complications among measles-vaccinated and unvaccinated children.

Vaccination schedule for children in Pakistan.

Age of vaccine administration Name of vaccine
Immediate after birth 1. BCG
2. OPV
3. Hepatitis-B
After 6 weeks 1. OPV-1
2. Penta-1
3. Pneumo-1
After 10 weeks 1. OPV-2
2. Penta-2
3. Pneumo-2
After 14 weeks 1. OPV-3
2. Penta-3
3. Pneumo-3
4. IPV
After 9 months Measles-1
After 15 months Measles-2

Demographic and related data of the patients.

Parameters Patient
Patient-related
Total Number 100
Male 48 (48%)
Female 52 (52%)
Age-wise (in months)
Male 15.06 (± 9.42)
Female 15.94 (± 9.42)
Feeding history (%)
Breastfeed 56%
Formula feed 32%
Breast + Formula 12%
Measles vaccination status (%)
Vaccinated (Total) 24%
        < 12 months (n = 2)
        12–24 months (n = 17)
        > 24 months (n = 5)
Unvaccinated (Total) 76%
        < 12 months (n = 42)
        12–24 months (n = 23)
        > 24 months (n = 11)
Vitamin A intake (both genders) 58%
Parents-related
Socio-economic status (%)
High (≥ $4,301 per annum) 12%
Middle (≥ $1,701 and ≤ $4,300 per annum) 38%
Lower (≤ $1,700 per annum) 50%
Educational status (%)
Higher 7%
Secondary 28%
Primary 22%
Uneducated 43%

Frequency and distribution of measles complications in different age groups of patients

Clinical complications Age-wise distribution
< 12 months 12–24 months > 24 months Total
Pneumonia 23 (47.9%) 15 (37.5%)   3 (25%)   41
LRTI   8 (16.7)   8 (20)%   2 (16.7%)   18
Otitis media   1 (2.5%)   1 (8.3%)     2
Acute diarrhea   4 (8.3%)   1 (2.5%)   1 (8.3%)     6
Diarrhea + LRTI*   6 (12.5%)   8 (20%)   3 (25%)   17
Pneumonia + Diarrhea   3 (6.25%)   2 (5%)   1 (8.3%)     6
Otitis media + Pneumonia   2 (4.1%)   1 (2.5%)   1 (8.3%)     4
Myocarditis + LRTI   1 (2.0%)   2 (5%)     3
SSPE   1 (2.5%)     1
Pneumothorax   1 (2.0%)   1 (2.5%)     2
Total 48 40 12 100
eISSN:
2544-4646
Idioma:
Inglés
Calendario de la edición:
4 veces al año
Temas de la revista:
Life Sciences, Microbiology and Virology