Thevenard’s Disease - a hereditary sensory and autonomic neuropathy type I / Thevenardova bolest - nasledna, senzorna i autonomna neuropatija tipa I

Thevenard’s Disease is a rare, hereditary sensory and autonomic neuropathy which leads to hyperkeratotyc and ulcerative lesions of the feet. We present two patients, a father and son, 39 and 18 years of age, in whom the disease first manifested in adolescence. Plantar hyperkeratosis and trophic, painless ulcerations occurred first, with subsequent feet deformities. Neurological and radiological findings pointed to chronic demyelination, polyneuropathy with damage to sensory fibers. Differential diagnosis and treatment options are discussed