Estimation of the impact of migraine on self-rated health: A cross-sectional study in Slovenia

Prevalence of poor self-rated health (PSRH) within categories of selected factors, with the results of the univariate analysis of the relationship between PSRH and these factors in the European Health Interview Survey, Slovenia 2014_

Risk factor	Category	N tot	Ndet/Ncat(%)	OR (95% CI limits for OR)	p
Migraine	No	6,213	350/5262 (6.7%)	1.00
	Yes		139/951 (13.7%)	2.22 (1.79–2.75)	<0.001
MIGRAINE COMORBIDITIES RELATED TO PHYSICAL DIMENSION OF HEALTH
Asthma/allergy	No	6,226	363/5007 (7.2%)	1.00
	Yes		122/1219 (10.0%)	1.41 (1.14–1.76)	0.001
COPD	No	6,239	408/5982 (6.8%)	1.00
	Yes		78/257 (30.4%)	5.90 (4.44–7.85)	<0.001
Ischemic heart disease	No	6,220	388/5964 (6.5%)	1.00
	Yes		96/256 (37.5%)	8.57 (6.52–11.26)	<0.001
Stroke	No	6,239	447/6145 (7.3%)	1.00
	Yes		37/94 (39.4%)	8.33 (5.45–12.73)	<0.001
Arterial hypertension	No	6,236	209/4690 (4.5%)	1.00
	Yes		275/1546 (17.8%)	4.63 (3.82–5.60)	<0.001
Diabetes mellitus	No	6,217	376/5790 (6.5%)	1.00
	Yes		110/427 (25.8%)	4.99 (3.92–6.35)	<0.001
Arthrosis	No	6,218	405/5940 (6.8%)	1.00
	Yes		79/278 (28.4%)	5.40 (4.08–7.14)	<0.001
Liver cirrhosis	No	6,219	467/6185 (7.6%)	1.00
	Yes		15/34 (44.1%)	9.40 (4.72–18.72)	<0.001
Cancer	No	6,209	444/6071 (7.3%)	1.00
	Yes		39/138 (29.3%)	4.95 (3.37–7.26)	<0.001
Urinary tract diseases	No	6,241	325/5494 (5.9%)	1.00
	Yes		161/747 (21.6%)	4.36 (3.54–5.37)	<0.001
MIGRAINE COMORBIDITIES RELATED TO MENTAL DIMENSION OF HEALTH
Mood disorders	No	6,209	312/5345 (5.8%)	1.00
	Yes		172/864 (19.9%)	4.00 (3.26–4.90)	<0.001
Poor sleep	No	6,262	284/5487 (5.2%)	1.00
	Yes		204/776 (26.3%)	6.54 (5.36–7.99)	<0.001
Spinal pain	No	6,234	104/3568 (2.9%)	1.00
	Yes		383/2666 (14.4%)	5.60 (4.48–7.00)	<0.001
DEMOGRAPHIC AND SOCIOECONOMIC FACTORS
Gender	Male	6,262	207/3082 (6.7%)	1.00
	Female		280/3180 (8.8%)	1.34 (1.11–1.61)	0.002
Married	No	6,255	249/3115 (8.0%)	1.00
	Yes		239/3148 (7.6%)	0.94 (0.78–1.13)	0.538
Low education level	No	6,201	147/3616 (4.1%)	1.00
	Yes		338/2585 (13.1%)	3.54 (2.90–4.33)	<0.001
Unemployed	No	6,262	93/2889 (3.2%)	1.00
	Yes		394/3321 (11.9%)	4.05 (3.21–5.11)	<0.001
Age	≤65 years	6,262	5054/245 (4.8%)	1.00
	>65 years		243/1208 (20.1%)	4.94 (4.08–5.98)	<0.001

Results of multivariate analysis of relationship between poor self-rated health (PSRH) and migraine adjusted for accompanying health conditions and demographic and socioeconomic factors in the European Health Interview Survey, Slovenia 2014 (Model 1: n=6042; Model 2: n=6015; Model 3: n=5946)_

Risk factor	Category	Model 1		Model 2		Model 3
		OR (95% CI limits for OR)	p	OR (95% CI limits for OR)	p	OR (95% CI limits for OR)	p
Migraine	No	1.00		1.00		1.00
	Yes	2.27 (1.77–2.91)	<0.001	1.51 (1.16–1.96)	0.002	1.56 (1.18–2.05)	0.001
MIGRAINE COMORBIDITIES RELATED TO PHYSICAL DIMENSION OF HEALTH
Asthma/allergy	No	1.00		1.00		1.00
	Yes	1.03 (0.80–1.33)	0.792	0.86 (0.65–1.12)	0.273	0.89 (0.68–1.17)	0.431
COPD	No	1.00		1.00		1.00
	Yes	4.24 (3.03–5.9)	<0.001	3.57 (2.52–5.05)	<0.001	3.41 (2.40–4.86)	<0.001
Ischemic heart disease	No	1.00		1.00		1.00
	Yes	3.89 (2.82–5.38)	<0.001	3.32 (2.37–4.64)	<0.001	2.77 (1.97–3.92)	<0.001
Arterial hypertension	No	1.00		1.00		1.00
	Yes	2.55 (2.04–3.18)	<0.001	2.08 (1.65–2.61)	<0.001	1.63 (1.28–2.08)	<0.001
Stroke	No	1.00		1.00		1.00
	Yes	2.30 (1.35–3.91)	0.002	2.60 (1.50–4.50)	0.001	2.31 (1.34–4.01)	0.003
Diabetes mellitus	No	1.00		1.00		1.00
	Yes	2.66 (1.98–3.57)	<0.001	2.60 (1.92–3.53)	<0.001	2.37 (1.74–3.22)	<0.001
Arthrosis	No	1.00		1.00		1.00
	Yes	2.11 (1.49–2.99)	<0.001	1.46 (1.02–2.09)	0.039	1.32 (0.92–1.91)	0.130
Liver cirrhosis	No	1.00		1.00		1.00
	Yes	6.78 (3.00–15.31)	<0.001	4.63 (2.08–10.30)	<0.001	4.04 (1.81–9.01)	0.001
Cancer	No	1.00		1.00		1.00
	Yes	2.57 (1.60–4.11)	<0.001	2.78 (1.72–4.49)	<0.001	2.75 (1.71–4.43)	<0.001
Urinary tract diseases	No	1.00		1.00		1.00
	Yes	2.15 (1.67–2.76)	<0.001	1.60 (1.23–2.08)	<0.001	1.31 (1.00–1.72)	0.045
MIGRAINE COMORBIDITIES RELATED TO MENTAL DIMENSION OF HEALTH
Spinal pain	No			1.00		1.00
	Yes			3.18 (2.46–4.11)	<0.001	3.02 (2.32–3.91)	<0.001
Mood disorders	No			1.00		1.00
	Yes			1.39 (1.07–1.80)	0.011	1.43 (1.09–1.84)	0.008
Poor sleep	No			1.00		1.00
	Yes			3.77 (2.97–4.80)	<0.001	3.63 (2.84–4.63)	<0.001
DEMOGRAPHIC AND SOCIOECONOMIC FACTORS
Gender	Male					1.00
	Female					0.95 (0.75–1.21)	0.711
Age	≤65 years					1.00
	>65 years					1.64 (1.25–2.51)	<0.001
Married	No					1.00
	Yes					0.77 (0.61–0.97)	0.029
Low education level	No					1.00
	Yes					1.84 (1.45–2.35)	<0.001
Unemployed	No					1.00
	Yes					1.36 (1.01–1.84)	0.037