<abstract xmlns="http://www.w3.org/1999/xhtml">

Granular cell tumor (GCT) is a rare form of soft tissue cancer that is usually benign. Its malignant evolution is encountered in less than 2% of cases, having a more rapid and unfavorable evolution. Clinical presentation betraying malignant features could be increased tumor size, rapid growth, deep localization, and female gender.
This paper presents the case of a 52-year-old patient with a hard, rapidly evolving tumor in the left arm. The diagnosis of granular cell tumor was made based on histopathological examination using the Fanburg and Smith criteria to differentiate the formation as malignant, but with certainty this was subsequently confirmed by the existence of a metastasis. Surgical excision was performed and the evolution was favorable.
Evolution and treatment differ depending on the benign or malignant form, but surgical treatment with wide local excision is recommended. This may be followed by chemotherapy or radiotherapy, and follow-up of patients for the rest of their lives is mandatory.
</abstract>

Granular cell tumor (GCT) is a rare form of soft tissue cancer that is usually benign. Its malignant evolution is encountered in less than 2% of cases, having a more rapid and unfavorable evolution. Clinical presentation betraying malignant features could be increased tumor size, rapid growth, deep localization, and female gender.
This paper presents the case of a 52-year-old patient with a hard, rapidly evolving tumor in the left arm. The diagnosis of granular cell tumor was made based on histopathological examination using the Fanburg and Smith criteria to differentiate the formation as malignant, but with certainty this was subsequently confirmed by the existence of a metastasis. Surgical excision was performed and the evolution was favorable.
Evolution and treatment differ depending on the benign or malignant form, but surgical treatment with wide local excision is recommended. This may be followed by chemotherapy or radiotherapy, and follow-up of patients for the rest of their lives is mandatory.

Malignant granular cell tumor of the arm – case report

Department of Plastic and Reconstructive Surgery

„Carol Davila” University of Medicine and Pharmacy

Romanian Journal of Orthopaedic Surgery and Traumatology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

{"article-title":"Malignant granular cell tumor of the arm \u2013 case report"}

Granular cell tumor (GCT) is a rare form of soft tissue cancer that is usually benign. Its malignant evolution is encountered in less than 2% of cases, having...

Malignant granular cell tumor of the arm – case report

Publicado en línea: 13 ago 2021

Páginas: 3 - 8

Aceptado: 09 jul 2021

DOI: https://doi.org/10.2478/rojost-2021-0002

Palabras clave
granular cell tumor, fine-needle aspiration biopsy, biceps brachii muscle, lymphatic tumoral invasion, soft tissue tumors, rhabdomyosarcoma

© 2021 Mihai Mehedinţu et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Malignant granular cell tumor of the arm – case report

Publicado en línea: 13 ago 2021

Páginas: 3 - 8

Aceptado: 09 jul 2021

DOI: https://doi.org/10.2478/rojost-2021-0002

Palabras clavegranular cell tumor, fine-needle aspiration biopsy, biceps brachii muscle, lymphatic tumoral invasion, soft tissue tumors, rhabdomyosarcoma

© 2021 Mihai Mehedinţu et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Palabras clave
granular cell tumor, fine-needle aspiration biopsy, biceps brachii muscle, lymphatic tumoral invasion, soft tissue tumors, rhabdomyosarcoma