<abstract xmlns="http://www.w3.org/1999/xhtml">

<bold>BACKGROUND.</bold> Extramedullary plasmacytoma is a rare tumor, representing less than 1% of head and neck tumors. This specific type of tumor occurs in 90% of cases in the upper aero-digestive tract, with more frequent location in 80% of cases in the submucosa.
<bold>CASE REPORT.</bold> We report the case of a 39-year-old young man who presented for bilateral nasal obstruction with swelling of the left nasal region and intermittent epistaxis of moderate abundance. The clinical examination revealed a tumor mass in the nasal cavity bleeding on contact, with the absence of nasal airflow. The cranio-facial CT and MRI imaging with contrast agent showed a large, locally advanced tumor in the left nasal cavity, with destruction of the surrounding osteo-cartilaginous structures. The anatomopathological study of the biopsy specimen returned in favour of a plasmacytoma of the nasal cavity with kappa light chains. The biological assessment of the multiple myeloma confirmed that it was an extramedullary plasmacytoma. Radiotherapy treatment was proposed.
<bold>CONCLUSION.</bold> In the light of this case of extramedullary plasmacytoma, we will discuss the clinical, therapeutic and evolutionary characteristics of this tumour.
</abstract>

BACKGROUND. Extramedullary plasmacytoma is a rare tumor, representing less than 1% of head and neck tumors. This specific type of tumor occurs in 90% of cases in the upper aero-digestive tract, with more frequent location in 80% of cases in the submucosa.
CASE REPORT. We report the case of a 39-year-old young man who presented for bilateral nasal obstruction with swelling of the left nasal region and intermittent epistaxis of moderate abundance. The clinical examination revealed a tumor mass in the nasal cavity bleeding on contact, with the absence of nasal airflow. The cranio-facial CT and MRI imaging with contrast agent showed a large, locally advanced tumor in the left nasal cavity, with destruction of the surrounding osteo-cartilaginous structures. The anatomopathological study of the biopsy specimen returned in favour of a plasmacytoma of the nasal cavity with kappa light chains. The biological assessment of the multiple myeloma confirmed that it was an extramedullary plasmacytoma. Radiotherapy treatment was proposed.
CONCLUSION. In the light of this case of extramedullary plasmacytoma, we will discuss the clinical, therapeutic and evolutionary characteristics of this tumour.

Extramedullary plasmacytoma of the nasal cavity with kappa light chains in a young person: A case report

Romanian Journal of Rhinology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

BACKGROUND. Extramedullary plasmacytoma is a rare tumor, representing less than 1% of head and neck tumors. This specific type of tumor occurs in 90% of cases...

Extramedullary plasmacytoma of the nasal cavity with kappa light chains in a young person: A case report

Publicado en línea: 18 jul 2022

Páginas: 140 - 145

Recibido: 28 abr 2022

Aceptado: 06 jun 2022

DOI: https://doi.org/10.2478/rjr-2022-0021

Palabras clave
plasmacytoma, myeloma, extramedullary, kappa, nasal cavities

© 2022 Zakaria Chekh Hammoud et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Extramedullary plasmacytoma of the nasal cavity with kappa light chains in a young person: A case report

Publicado en línea: 18 jul 2022

Páginas: 140 - 145

Recibido: 28 abr 2022

Aceptado: 06 jun 2022

DOI: https://doi.org/10.2478/rjr-2022-0021

Palabras claveplasmacytoma, myeloma, extramedullary, kappa, nasal cavities

© 2022 Zakaria Chekh Hammoud et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Palabras clave
plasmacytoma, myeloma, extramedullary, kappa, nasal cavities