<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Small cell neuroendocrine carcinoma (SCNEC) of the nasopharynx and nasal cavity is a rare condition. It is an aggressive malignancy with a high recurrence rate. Despite its rarity in the sinonasal region, it may occur as a second primary malignancy. Patients with cancer of the head and neck region are more prone to develop a second primary tumor due to the field cancerization phenomenon, and a higher incidence is seen in those who have previously received radiation therapy. A detailed clinical and histopathological examination is pivotal to diagnose SCNEC as a second primary malignancy. We wish to highlight such a peculiar case from our center.</p></abstract>

Small cell neuroendocrine carcinoma (SCNEC) of the nasopharynx and nasal cavity is a rare condition. It is an aggressive malignancy with a high recurrence rate. Despite its rarity in the sinonasal region, it may occur as a second primary malignancy. Patients with cancer of the head and neck region are more prone to develop a second primary tumor due to the field cancerization phenomenon, and a higher incidence is seen in those who have previously received radiation therapy. A detailed clinical and histopathological examination is pivotal to diagnose SCNEC as a second primary malignancy. We wish to highlight such a peculiar case from our center.

Small cell neuroendocrine carcinoma: A rare second primary malignancy after treatment of nasopharyngeal carcinoma

Department of Ear, Nose, Throat and Head &Neck Surgery, Hospital Ampang

Ear, Nose, Throat and Head &Neck Surgery Department, Hospital Ampang

Romanian Journal of Rhinology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Small cell neuroendocrine carcinoma (SCNEC) of the nasopharynx and nasal cavity is a rare condition. It is an aggressive malignancy with a high recurrence...

Small cell neuroendocrine carcinoma: A rare second primary malignancy after treatment of nasopharyngeal carcinoma

Publicado en línea: 25 jul 2018

Páginas: 187 - 192

Recibido: 20 may 2018

Aceptado: 12 jun 2018

DOI: https://doi.org/10.2478/rjr-2018-0021

Palabras clave
neuroendocrine carcinoma, nasopharyngeal carcinoma, second primary malignancy, small cell carcinoma

© 2018 Krishnamoorthy Madhusudhan et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Small cell neuroendocrine carcinoma: A rare second primary malignancy after treatment of nasopharyngeal carcinoma

Publicado en línea: 25 jul 2018

Páginas: 187 - 192

Recibido: 20 may 2018

Aceptado: 12 jun 2018

DOI: https://doi.org/10.2478/rjr-2018-0021

Palabras claveneuroendocrine carcinoma, nasopharyngeal carcinoma, second primary malignancy, small cell carcinoma

© 2018 Krishnamoorthy Madhusudhan et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Palabras clave
neuroendocrine carcinoma, nasopharyngeal carcinoma, second primary malignancy, small cell carcinoma