<abstract xmlns="http://www.w3.org/1999/xhtml">

<sec id="j_raon-2022-0041_s_006"><h3>Background</h3>
<p>Although cardiac myxoma (CM) are rare and benign, they can cause life-threatening complications, such as hemodynamic disturbances or embolization. Surgical excision of the tumour is the treatment of choice. The aim of the study was to evaluate the epidemiological characteristics, clinical presentation, imaging findings, and outcomes of surgical treatment of patients with CM treated in the largest tertiary care centre in Slovenia.</p></sec>
<sec id="j_raon-2022-0041_s_007"><h3>Patients and methods</h3>
<p>We retrospectively analysed the medical records of all patients referred to our institution between January 2005 and December 2020 and identified 39 consecutive adult patients with pathologically confirmed CM.</p></sec>
<sec id="j_raon-2022-0041_s_008"><h3>Results</h3>
<p>The average annual incidence of CM in the study was 3 per 2 million population per year. Patients were more often female (n = 25, 64%). The mean age at diagnosis was 63.1 ± 13.6 years. Dyspnoea was the most common presenting symptom (31%). CM was an incidental finding in 11 patients (28%). Seven patients presented with thromboembolic event (18%). Transthoracic echocardiography (TTE) was performed in all patients, however additional imaging was required in 22 patients (56%). All patients in our series were successfully treated surgically without in-hospital mortality. During the follow-up period (6 months to 16 years) three patients (8%) died, and all deaths were unrelated to CM. There was no recurrence of CM during the follow-up.</p></sec>
<sec id="j_raon-2022-0041_s_009"><h3>Conclusions</h3>
<p>Our single-centre study confirms that CM is rare cardiac tumour with diverse clinical presentation. Our data shows data that CM might be more prevalent than considered before. Surgical resection of the tumour is safe with excellent short- and long-term outcomes.</p></sec>
</abstract>

Background
Although cardiac myxoma (CM) are rare and benign, they can cause life-threatening complications, such as hemodynamic disturbances or embolization. Surgical excision of the tumour is the treatment of choice. The aim of the study was to evaluate the epidemiological characteristics, clinical presentation, imaging findings, and outcomes of surgical treatment of patients with CM treated in the largest tertiary care centre in Slovenia.
Patients and methods
We retrospectively analysed the medical records of all patients referred to our institution between January 2005 and December 2020 and identified 39 consecutive adult patients with pathologically confirmed CM.
Results
The average annual incidence of CM in the study was 3 per 2 million population per year. Patients were more often female (n = 25, 64%). The mean age at diagnosis was 63.1 ± 13.6 years. Dyspnoea was the most common presenting symptom (31%). CM was an incidental finding in 11 patients (28%). Seven patients presented with thromboembolic event (18%). Transthoracic echocardiography (TTE) was performed in all patients, however additional imaging was required in 22 patients (56%). All patients in our series were successfully treated surgically without in-hospital mortality. During the follow-up period (6 months to 16 years) three patients (8%) died, and all deaths were unrelated to CM. There was no recurrence of CM during the follow-up.
Conclusions
Our single-centre study confirms that CM is rare cardiac tumour with diverse clinical presentation. Our data shows data that CM might be more prevalent than considered before. Surgical resection of the tumour is safe with excellent short- and long-term outcomes.

Cardiac myxoma: single tertiary centre experience

Radiology and Oncology

This work is licensed under the Creative Commons Attribution 4.0 International License.

{"article-title":"Cardiac myxoma: single tertiary centre experience"}

Background
Although cardiac myxoma (CM) are rare and benign, they can cause life-threatening complications, such as hemodynamic disturbances or embolization....

Characteristic	n (%)
Sex
Female	25 (64)
Rhythm
Sinus rhythm	37 (95)
Clinical presentation*
Dyspnea	12 (31)
Chest pain	6 (15)
Embolism	7 (18)
- Cerebrovascular	6
- Coronary artery	1
Palpitations	1 (3)
Constitutional signs	2 (5)
Asymptomatic	11 (28)

Characteristic	n (%)
Location
- Left atrium	33 (85)
- Right atrium	6 (15)
Post-operative complications	7 (18)
- Arrhythmia*	6 (86)
- Pleural effusion*	1
- Surgical site infection	1

Cardiac myxoma: single tertiary centre experience

Article Category: Research Article

Publicado en línea: 20 oct 2022

Páginas: 535 - 540

Recibido: 24 jun 2022

Aceptado: 12 sept 2022

DOI: https://doi.org/10.2478/raon-2022-0041

© 2022 Polona Kacar, Nejc Pavsic, Mojca Bervar, Zvezdana Dolenc Strazar, Vesna Zadnik, Matija Jelenc, Katja Prokselj, published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Figure 1

Figure 2

Figure 3

Figure 4

Figure 5

Demographic and clinical characteristics

Surgical results and follow-up