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Verification of an optimizer algorithm by the beam delivery evaluation of intensity-modulated arc therapy plans

Tamas Pocza
Tamas Pocza
, 
Domonkos Szegedi
Domonkos Szegedi
, 
Tibor Major
Tibor Major
 y 
Csilla Pesznyak
Csilla Pesznyak
   | 19 nov 2021
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Article Category: Research Article
Publicado en línea: 19 nov 2021
Páginas: 508 - 515
Recibido: 25 jun 2021
Aceptado: 17 ago 2021
DOI: https://doi.org/10.2478/raon-2021-0046
© 2021 Tamas Pocza, Domonkos Szegedi, Tibor Major, Csilla Pesznyak, published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Figure 1

(A) The average value of gamma passing rates according to the used optimization separated by normalization, and the gamma passing rates according to the normalization (B) and optimization (C) dose values.
(A) The average value of gamma passing rates according to the used optimization separated by normalization, and the gamma passing rates according to the normalization (B) and optimization (C) dose values.

Figure 2

The effect of the normalization dose (A) and the optimization dose (B) values on the aperture complexity metric (ACM) score.
The effect of the normalization dose (A) and the optimization dose (B) values on the aperture complexity metric (ACM) score.

Figure 3

The connection between the complexity score and the gamma passing rate.
The connection between the complexity score and the gamma passing rate.

Figure 4

The effect of the average gantry speed (A) and standard deviation (B), and the average dose rate (C) and standard deviation (D) on the gamma passing rates.
The effect of the average gantry speed (A) and standard deviation (B), and the average dose rate (C) and standard deviation (D) on the gamma passing rates.

Figure 5

The predicted and measured number of maximum (blue) and the central-axis (red) calibrated units (CU) for 1 Gy according to the fraction dose.PDIP = portal dose image prediction;
The predicted and measured number of maximum (blue) and the central-axis (red) calibrated units (CU) for 1 Gy according to the fraction dose.PDIP = portal dose image prediction;

The parameters of the selected patients and irradiated volumes

Sex Age [years] Lobe GTV_volume [ccm] Tumor movement [mm] ITV_volume [ccm] PTV_volume [ccm]
Male 84 Right-lower 3.7 20 10.7 33.3
Male 66 Left-upper 1.3 4 2.2 11.5
Male 72 Left-upper 4.8 5 7.2 24.9
Female 61 Right-mid 2.6 4 3.9 15.1
Female 67 Right-mid 0.7 2 1.1 7.6

The mean values and the standard deviations of the plan quality parameters

2 Gy/fraction 3 Gy/fraction 6 Gy/fraction 12 Gy/fraction 20 Gy/fraction
PTV_Dmean (cGy) 6706±96 6713±85 6701±97 6715±91 6686±96
PTV_V95 (%) 98.17±2.34 98.44±1.61 98.32±1.72 98.43±1.67 98.22±1.93
PTV_V100 (%) 91.12±5.29 91.85±4.34 91.31±4.63 91.82±4.54 90.78±4.93
PTV_V98 (%) 94.9±4.24 95.47±3.28 94.97±3.54 95.39±3.48 94.75±3.84
PTV_D98 (cGy) 5759±141 5771±116 5760±128 5773±126 5755±128
PTV_D50 (cGy) 6749±128 6762±107 6750±125 6760±119 6726±125
PTV_D2 (cGy) 7515±114 7472±94 7461±106 7487±91 7454±87
ITV_Dmean (cGy) 7234±150 7229±126 7113±301 7124±262 7106±272
ITV_D98 (cGy) 6867±130 6901±101 6862±152 6877±125 6848±144
ITV_D50 (cGy) 7242±154 7229±134 7221±145 7238±117 7219±105
ITV_D2 (cGy) 7581±164 7556±162 7531±150 7561±142 7539±166
BODY_V100 (ccm) 17.1±9.56 17.25±9.64 17.13±9.66 17.24±9.72 17.16±9.57
BODY_V50 (ccm) 75.02±35.16 75.09±35.17 74.96±35.68 75.31±35.79 74.74±35.45
BODY_V98 (ccm) 18.2±10.03 18.34±10.11 18.22±10.13 18.34±10.19 18.1±10.16
Dmax (cGy) 7816±128 7777±106 7731±106 7794±16 7691±288
Lung_V5Gy (%) 15.57±7.25 15.51±7.31 15.59±7.24 15.57±7.3 15.56±7.26
Lung_V20Gy (%) 4.25±2.32 4.28±2.33 4.25±2.33 4.27±2.34 4.26±2.34
Lung_Dmean (cGy) 342±148 343±149 342±149 343±149 342±149
# MU / cGy 2.84±0.15 2.81±0.1 2.8±0.12 2.81±0.11 2.81±0.12
R50% 4.27±0.52 4.27±0.51 4.25±0.51 4.27±0.5 4.24±0.49
CI98%_PTV 0.93±0.06 0.94±0.05 0.93±0.06 0.94±0.05 0.94±0.06
CN98%_PTV 0.9±0.03 0.91±0.02 0.91±0.02 0.91±0.02 0.91±0.03
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