<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Bone density of the femur body of rabbit was determined <italic>in vivo</italic>. Experimental osteoporosis was induced by ovariectomy and subsequent injections of methylprednisolone. In the greater trochanter region of right femur, defects were created and filled with granules of hydroxyapatite and tricalcium phosphate (HAP/TCP 70/30) or HAP/TCP 70/30 together with 5% strontium. After three months, the animals were euthanized. The bone mass density of the right and left body of femur was measured by cone beam computed tomography (CT) scan. The results of the study showed that the right femur of the rabbit, where biomaterials had been implanted, and the left femur, where no biomaterial implantation occurred, became denser after filling the defect with HAP/TCP 70/30 ceramic granules or 5% Sr modified HAP/TCP ceramic granules. There was no difference between operated and non-operated legs and HAP/TCP and HAP/TCP with 5% strontium groups.</p></abstract>

Bone density of the femur body of rabbit was determined in vivo. Experimental osteoporosis was induced by ovariectomy and subsequent injections of methylprednisolone. In the greater trochanter region of right femur, defects were created and filled with granules of hydroxyapatite and tricalcium phosphate (HAP/TCP 70/30) or HAP/TCP 70/30 together with 5% strontium. After three months, the animals were euthanized. The bone mass density of the right and left body of femur was measured by cone beam computed tomography (CT) scan. The results of the study showed that the right femur of the rabbit, where biomaterials had been implanted, and the left femur, where no biomaterial implantation occurred, became denser after filling the defect with HAP/TCP 70/30 ceramic granules or 5% Sr modified HAP/TCP ceramic granules. There was no difference between operated and non-operated legs and HAP/TCP and HAP/TCP with 5% strontium groups.

General Influence of Biphasic Calcium Phosphate on Osteoporotic Bone Density

Department of Oral and Maxillofacial Surgery

Faculty of Continuing Education, Study Programme Residency in Medicine

Proceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences.

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

{"article-title":"General Influence of Biphasic Calcium Phosphate on Osteoporotic Bone Density"}

Bone density of the femur body of rabbit was determined in vivo. Experimental osteoporosis was induced by ovariectomy and subsequent injections of...

General Influence of Biphasic Calcium Phosphate on Osteoporotic Bone Density

Publicado en línea: 07 abr 2019

Páginas: 185 - 188

Recibido: 07 nov 2018

Aceptado: 19 feb 2019

DOI: https://doi.org/10.2478/prolas-2019-0029

Palabras clave
bone density, osteoporosis, biphasic calcium phosphate, strontium

© 2019 Vladislavs Ananjevs et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

General Influence of Biphasic Calcium Phosphate on Osteoporotic Bone Density

Publicado en línea: 07 abr 2019

Páginas: 185 - 188

Recibido: 07 nov 2018

Aceptado: 19 feb 2019

DOI: https://doi.org/10.2478/prolas-2019-0029

Palabras clavebone density, osteoporosis, biphasic calcium phosphate, strontium

© 2019 Vladislavs Ananjevs et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Palabras clave
bone density, osteoporosis, biphasic calcium phosphate, strontium