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Transcriptome analysis of bovine macrophages (BoMac) cells after infection with bovine immunodeficiency virus

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26 dic 2022

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Appelberg K.S., Wallet M.A., Taylor J.P., Cash M.N., Sleasman J.W., Goodenow M.M.: HIV-1 infection primes macrophages through STAT signalling to promote enhanced inflammation and viral replication. AIDS Res Hum Retroviruses 2017, 33, 690–702, doi: 10.1089/aid.2016.0273. Appelberg K.S. Wallet M.A. Taylor J.P. Cash M.N. Sleasman J.W. Goodenow M.M. HIV-1 infection primes macrophages through STAT signalling to promote enhanced inflammation and viral replication AIDS Res Hum Retroviruses 2017 33 690 702 10.1089/aid.2016.0273.Open DOISearch in Google Scholar

Brown J.N., Kohler J.J., Coberley C.R., Sleasman J.W., Goodenow M.M.: HIV-1 activates macrophages independent of Toll-Like Receptors. PLoS One 2008, 3, e3664, doi: 10.1371/journal.pone.0003664. Brown J.N. Kohler J.J. Coberley C.R. Sleasman J.W. Goodenow M.M. HIV-1 activates macrophages independent of Toll-Like Receptors PLoS One 2008 3 e3664 10.1371/journal.pone.0003664.Open DOISearch in Google Scholar

Brym P., Ruść A., Kamiński S.: Evaluation of reference genes for qRT-PCR gene expression studies in whole blood samples from healthy and leukemia-virus infected cattle. Vet Immunol Immunopathol 2013, 153, 302–307, doi: 10.1016/j.vetimm.2013.03.004. Brym P. Ruść A. Kamiński S. Evaluation of reference genes for qRT-PCR gene expression studies in whole blood samples from healthy and leukemia-virus infected cattle Vet Immunol Immunopathol 2013 153 302 307 10.1016/j.vetimm.2013.03.004.Open DOISearch in Google Scholar

Carlberg C.: Vitamin D signaling in the context of innate immunity: focus on human monocytes. Front Immunol 2019, 10, doi: 10.3389/fimmu.2019.02211. Carlberg C. Vitamin D signaling in the context of innate immunity: focus on human monocytes Front Immunol 2019 10 10.3389/fimmu.2019.02211.Open DOISearch in Google Scholar

Carpenter S., Miller L.D., Alexandersen S., Whetstone C.A., Van Der Maaten M.J., Viuff B., Wannemuehler Y., Miller J.M., Roth J.A.: Characterization of early pathogenic effects after experimental infection of calves with bovine immunodeficiency-like virus. J Virol 1992, 66, 1074–1083, doi: 10.1128/jvi.66.2.1074-1083.1992. Carpenter S. Miller L.D. Alexandersen S. Whetstone C.A. Van Der Maaten M.J. Viuff B. Wannemuehler Y. Miller J.M. Roth J.A. Characterization of early pathogenic effects after experimental infection of calves with bovine immunodeficiency-like virus J Virol 1992 66 1074 1083 10.1128/jvi.66.2.1074-1083.1992.Open DOISearch in Google Scholar

Cho K.O., Meas S., Park N.Y., Kim Y.H., Lim Y.K., Endoh D., Lee S.I., Pjasjo K., Sugimoto C., Onuma M.: Seroprevalence of bovine immunodeficiency virus in dairy and beef cattle herds in Korea. J Vet Med Sci 1999, 61, 549–551, doi: 10.1292/jvms.61.549. Cho K.O. Meas S. Park N.Y. Kim Y.H. Lim Y.K. Endoh D. Lee S.I. Pjasjo K. Sugimoto C. Onuma M. Seroprevalence of bovine immunodeficiency virus in dairy and beef cattle herds in Korea J Vet Med Sci 1999 61 549 551 10.1292/jvms.61.549.Open DOISearch in Google Scholar

Corredor A., St-Louis M.C., Archambault D.: Molecular and biological aspects of the bovine immunodeficiency virus. Curr HIV Res 2010, 8, 2–13, doi: 10.2174/157016210790416343. Corredor A. St-Louis M.C. Archambault D. Molecular and biological aspects of the bovine immunodeficiency virus Curr HIV Res 2010 8 2 13 10.2174/157016210790416343.Open DOISearch in Google Scholar

Covino D.A., Kaczor-Urbanowicz K.E., Lu J., Chiantore M.V., Fiorucci G., Vescio M.F., Catapano L., Purificato C., Galluzz C.M., Amici R., Andreotti M., Gauzzi M.C., Pellegrini M., Fantuzzi L.: Transcriptome profiling of human monocyte-derived macrophages upon CCL2 neutralization reveals an association between activation of innate immune pathways and restriction of HIV-1 gene expression. Front Immunol 2020, 11, doi: 10.3389/fimmu.2020.02129. Covino D.A. Kaczor-Urbanowicz K.E. Lu J. Chiantore M.V. Fiorucci G. Vescio M.F. Catapano L. Purificato C. Galluzz C.M. Amici R. Andreotti M. Gauzzi M.C. Pellegrini M. Fantuzzi L. Transcriptome profiling of human monocyte-derived macrophages upon CCL2 neutralization reveals an association between activation of innate immune pathways and restriction of HIV-1 gene expression Front Immunol 2020 11 10.3389/fimmu.2020.02129.Open DOISearch in Google Scholar

Desport M., Lewis J.: Jembrana disease virus: host responses, viral dynamics and disease control. Curr HIV Res 2010, 8, 53–65, doi: 10.2174/157016210790416370. Desport M. Lewis J. Jembrana disease virus: host responses, viral dynamics and disease control Curr HIV Res 2010 8 53 65 10.2174/157016210790416370.Open DOISearch in Google Scholar

Desport M., McLachlan S.: The Bovine Lentiviruses: Pathogenesis and Cell Tropism. In: Lentiviruses and Macrophages: Molecular and Cellular Interactions, edited by M. Desport, Caister Academic Press, Poole, 2010, pp. 307–327. Desport M. McLachlan S. The Bovine Lentiviruses: Pathogenesis and Cell Tropism In Lentiviruses and Macrophages: Molecular and Cellular Interactions edited by Desport M. Caister Academic Press Poole 2010 pp 307 327Search in Google Scholar

Eberly M.D., Kader M., Hassan W., Rogers K.A., Zhou J., Mueller Y.M., Mattapallil M.J., Piatak M., Lifson J.D., Katsikis P.D., Roederer M., Villinger F., Mattapallilet J.J.: Increased IL-15production is associated with higher susceptibility of memory CD4 T cells to simian immunodeficiency virus during acute infection. J Immunol 2009, 182, 1439–1448, doi: 10.4049/jimmunol.182.3.1439. Eberly M.D. Kader M. Hassan W. Rogers K.A. Zhou J. Mueller Y.M. Mattapallil M.J. Piatak M. Lifson J.D. Katsikis P.D. Roederer M. Villinger F. Mattapallilet J.J. Increased IL-15production is associated with higher susceptibility of memory CD4 T cells to simian immunodeficiency virus during acute infection J Immunol 2009 182 1439 1448 10.4049/jimmunol.182.3.1439.Open DOISearch in Google Scholar

Gavegnano C., Brehm J.H., Dupuy F.P., Talla A., Ribeiro S.P., Kulpa D.A., Cameron C., Santos S., Hurwitz S.J., Marconi V.C., Routy J.P., Sabbagh L., Schinazi R.F., Sékalyet R.P.: Novel mechanisms to inhibit HIV reservoir seeding using Jak inhibitors. PLOS Pathog 2017, 13, e1006740, doi: 10.1371/journal.ppat.1006740. Gavegnano C. Brehm J.H. Dupuy F.P. Talla A. Ribeiro S.P. Kulpa D.A. Cameron C. Santos S. Hurwitz S.J. Marconi V.C. Routy J.P. Sabbagh L. Schinazi R.F. Sékalyet R.P. Novel mechanisms to inhibit HIV reservoir seeding using Jak inhibitors PLOS Pathog 2017 13 e1006740 10.1371/journal.ppat.1006740.Open DOISearch in Google Scholar

Gonda M.A., Braun M.J., Carter S.G., Kost T.A., Bess J.W., Arthur L.O., Van Der Maaten M.J.: Characterization and molecular cloning of a bovine lentivirus related to human immunodeficiency virus. Nature 1987, 330, 388–391, doi: 10.1038/330388a0. Gonda M.A. Braun M.J. Carter S.G. Kost T.A. Bess J.W. Arthur L.O. Van Der Maaten M.J. Characterization and molecular cloning of a bovine lentivirus related to human immunodeficiency virus Nature 1987 330 388 391 10.1038/330388a0.Open DOISearch in Google Scholar

Gonda M.A., Luther D.G., Fong S.E., Tobin G.J.: Bovine immunodeficiency virus: molecular biology and virus-host interactions. Virus Res 1994, 32, 155–181, doi: 10.1016/0168-1702(94)90040-X. Gonda M.A. Luther D.G. Fong S.E. Tobin G.J. Bovine immunodeficiency virus: molecular biology and virus-host interactions Virus Res 1994 32 155 181 10.1016/0168-1702(94)90040-X.Open DOISearch in Google Scholar

González‐Fernández V.D., Tórtora Pérez J.L., García Flores M.M., Aguilar Setién J.Á., Ramírez Álvarez H.: First evidence of bovine immunodeficiency virus infection in Mexican cattle. Transbound Emerg Dis 2020, 67, 1768–1775, doi: 10.1111/tbed.13530. González‐Fernández V.D. Tórtora Pérez J.L. García Flores M.M. Aguilar Setién J.Á. Ramírez Álvarez H. First evidence of bovine immunodeficiency virus infection in Mexican cattle Transbound Emerg Dis 2020 67 1768 1775 10.1111/tbed.13530.Open DOISearch in Google Scholar

Hidalgo G., Flores M., Bonilla J.A.: Detection and isolation of bovine immunodeficiency-like virus (BIV) in dairy herds of Costa Rica. J Vet Med Ser B 1995, 42, 155–161, doi: 10.1111/j.1439-0450.1995.tb00696.x. Hidalgo G. Flores M. Bonilla J.A. Detection and isolation of bovine immunodeficiency-like virus (BIV) in dairy herds of Costa Rica J Vet Med Ser B 1995 42 155 161 10.1111/j.1439-0450.1995.tb00696.x.Open DOISearch in Google Scholar

Horzinek M., Keldermans L., Stuurman T., Black J., Herrewegh A., Sillekens P., Koolen M.: Bovine immunodeficiency virus, immunochemical characterization and serological survey. J Gen Virol 1991, 72, 2923–2928, doi: 10.1099/0022-1317-72-12-2923. Horzinek M. Keldermans L. Stuurman T. Black J. Herrewegh A. Sillekens P. Koolen M. Bovine immunodeficiency virus, immunochemical characterization and serological survey J Gen Virol 1991 72 2923 2928 10.1099/0022-1317-72-12-2923.Open DOISearch in Google Scholar

Ihim S.A., Abubakar S.D., Zian Z., Sasaki T., Saffarioun M., Maleknia S., Azizi G.: Interleukin-18 cytokine in immunity, inflammation, and autoimmunity: Biological role in induction, regulation, and treatment. Front Immunol 2022, 13, doi: 10.3389/fimmu.2022.919973. Ihim S.A. Abubakar S.D. Zian Z. Sasaki T. Saffarioun M. Maleknia S. Azizi G. Interleukin-18 cytokine in immunity, inflammation, and autoimmunity: Biological role in induction, regulation, and treatment Front Immunol 2022 13 10.3389/fimmu.2022.919973.Open DOISearch in Google Scholar

Kotowski K., Rosik J., Machaj F., Supplitt S., Wiczew D., Jabłońska K., Wiechec E., Ghavami S., Dzięgiel P.: Role of PFKFB3 and PFKFB4 in cancer: genetic basis, impact on disease development/progression, and potential as therapeutic targets. Cancers (Basel) 2021, 13, 909, doi:10.3390/cancers13040909. Kotowski K. Rosik J. Machaj F. Supplitt S. Wiczew D. Jabłońska K. Wiechec E. Ghavami S. Dzięgiel P. Role of PFKFB3 and PFKFB4 in cancer: genetic basis, impact on disease development/progression, and potential as therapeutic targets Cancers (Basel) 2021 13 909 10.3390/cancers13040909.Open DOISearch in Google Scholar

Meas S., Ohashi K., Tum S., Chhin M., Te K., Miura K., Sugimoto C., Onuma M.: Seroprevalence of bovine immunodeficiency virus and bovine leukemia virus in draught animals in Cambodia. J Vet Med Sci 2000, 62, 779–781, doi: 10.1292/jvms.62.779. Meas S. Ohashi K. Tum S. Chhin M. Te K. Miura K. Sugimoto C. Onuma M. Seroprevalence of bovine immunodeficiency virus and bovine leukemia virus in draught animals in Cambodia J Vet Med Sci 2000 62 779 781 10.1292/jvms.62.779.Open DOISearch in Google Scholar

Muller W.A.: Getting leukocytes to the site of inflammation. Vet Pathol 2013, 50, 7–22, doi: 10.1177/0300985812469883. Muller W.A. Getting leukocytes to the site of inflammation Vet Pathol 2013 50 7 22 10.1177/0300985812469883.Open DOISearch in Google Scholar

Muluneh A.: Seroprevalence of bovine immunodeficiency-virus (BIV) antibodies in the cattle population in Germany. J Vet Med Ser B 1994, 41, 679–684, doi: 10.1111/j.1439-0450.1994.tb00280.x. Muluneh A. Seroprevalence of bovine immunodeficiency-virus (BIV) antibodies in the cattle population in Germany J Vet Med Ser B 1994 41 679 684 10.1111/j.1439-0450.1994.tb00280.x.Open DOISearch in Google Scholar

Munro R., Lysons R., Venables C., Horigan M., Jeffrey M., Dawson M.: Lymphadenopathy and non-suppurative meningo-encephalitis in calves experimentally infected with bovine immunodeficiency-like virus (FL112). J Comp Pathol 1998, 119, 121–134, doi: 10.1016/S0021-9975(98)80057-1. Munro R. Lysons R. Venables C. Horigan M. Jeffrey M. Dawson M. Lymphadenopathy and non-suppurative meningo-encephalitis in calves experimentally infected with bovine immunodeficiency-like virus (FL112) J Comp Pathol 1998 119 121 134 10.1016/S0021-9975(98)80057-1.Open DOISearch in Google Scholar

Nelson C.D., Reinhard T.A., Thacker T.C., Beitz D.C., Lippolis J.D.: Modulation of the bovine innate immune response by production of 1α,25-dihydroxyvitamin D3 in bovine monocytes. J Dairy Sci 2010, 93, 1041–1049, doi: 10.3168/jds.2009-2663. Nelson C.D. Reinhard T.A. Thacker T.C. Beitz D.C. Lippolis J.D. Modulation of the bovine innate immune response by production of 1α,25-dihydroxyvitamin D3 in bovine monocytes J Dairy Sci 2010 93 1041 1049 10.3168/jds.2009-2663.Open DOISearch in Google Scholar

Onuma M., Koomto E., Furuyama H., Yasutomi Y., Taniyama H., Iwai H., Kawakami Y.: Infection and dysfunction of monocytes induced by experimental inoculation of calves with bovine immunodeficiency like virus. J Acquir Immune Defic Syndr 1992, 5, 1009–1015. Onuma M. Koomto E. Furuyama H. Yasutomi Y. Taniyama H. Iwai H. Kawakami Y. Infection and dysfunction of monocytes induced by experimental inoculation of calves with bovine immunodeficiency like virus J Acquir Immune Defic Syndr 1992 5 1009 1015Search in Google Scholar

Pfaffl M.W.: A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 2001, 29, 45e–45, doi: 10.1093/nar/29.9.e45. Pfaffl M.W. A new mathematical model for relative quantification in real-time RT-PCR Nucleic Acids Res 2001 29 45e 45 10.1093/nar/29.9.e45.Open DOISearch in Google Scholar

Rola-Łuszczak M., Kozaczyńska B., Kuźmak J.: Serological survey for bovine immunodeficiency virus in dairy cattle from Poland. Pol J Vet Sci 2011, 14, 579–583, doi: 10.2478/v10181-011-0086-8. Rola-Łuszczak M. Kozaczyńska B. Kuźmak J. Serological survey for bovine immunodeficiency virus in dairy cattle from Poland Pol J Vet Sci 2011 14 579 583 10.2478/v10181-011-0086-8.Open DOISearch in Google Scholar

StCyr Coats K., Pruett S.B., Nash J.W., Cooper C.R.: Bovine immunodeficiency virus, incidence of infection in Mississippi dairy cattle. Vet Microbiol 1994, 42, 181–189, doi: 10.1016/03781135(94)90017-5. StCyr Coats K. Pruett S.B. Nash J.W. Cooper C.R. Bovine immunodeficiency virus, incidence of infection in Mississippi dairy cattle Vet Microbiol 1994 42 181 189 10.1016/03781135(94)90017-5.Open DOISearch in Google Scholar

Snider T.G., Hoyt P.G., Coats K.S., Graves K.F., Cooper C.R., Storts R.W., Luther D.G., Jenny B.F.: Natural bovine lentiviral type 1 infection in Holstein dairy cattle. I. Clinical, serological, and pathological observations. Comp Immunol Microbiol Infect Dis 2003, 26, 89–101, doi: 10.1016/S0147-9571(02)00021-8. Snider T.G. Hoyt P.G. Coats K.S. Graves K.F. Cooper C.R. Storts R.W. Luther D.G. Jenny B.F. Natural bovine lentiviral type 1 infection in Holstein dairy cattle I. Clinical, serological, and pathological observations. Comp Immunol Microbiol Infect Dis 2003 26 89 101 10.1016/S0147-9571(02)00021-8.Open DOISearch in Google Scholar

Stabel J.R., Stabel T.J.: Immortalization and characterization of bovine peritoneal macrophages transfected with SV40 plasmid DNA. Vet Immunol Immunopathol 1995, 45, 211–220, doi: 10.1016/0165-2427(94)05348-V. Stabel J.R. Stabel T.J. Immortalization and characterization of bovine peritoneal macrophages transfected with SV40 plasmid DNA Vet Immunol Immunopathol 1995 45 211 220 10.1016/0165-2427(94)05348-V.Open DOISearch in Google Scholar

Suarez D.L., Van Der Maaten M.J., Wood C., Whetstone C.A.: Isolation and characterization of new wild-type isolates of bovine lentivirus. J Virol 1993, 67, 5051–5055, doi: 10.1128/jvi.67.8.5051-5055.1993. Suarez D.L. Van Der Maaten M.J. Wood C. Whetstone C.A. Isolation and characterization of new wild-type isolates of bovine lentivirus J Virol 1993 67 5051 5055 10.1128/jvi.67.8.5051-5055.1993.Open DOISearch in Google Scholar

Swaminathan S., Qiu J., Rupert A.W., Hu Z., Higgins J., Dewar R.L., Stevens R., Rehm C.A., Metcalf J.A., Sherma B.T., Baseler M.W., Clifford H., Imamichi T.: Interleukin-15 (IL-15) strongly correlates with increasing HIV-1 viremia and markers of inflammation. PLoS One 2016, 11, e0167091, doi: 10.1371/journal.pone.0167091. Swaminathan S. Qiu J. Rupert A.W. Hu Z. Higgins J. Dewar R.L. Stevens R. Rehm C.A. Metcalf J.A. Sherma B.T. Baseler M.W. Clifford H. Imamichi T. Interleukin-15 (IL-15) strongly correlates with increasing HIV-1 viremia and markers of inflammation PLoS One 2016 11 e0167091 10.1371/journal.pone.0167091.Open DOISearch in Google Scholar

Tsang J., Chain B.M., Miller R.F., Webb B.L., Barclay W., Towers G.J., Katz D.R., Noursadeghi M.: HIV-1 infection of macrophages is dependent on evasion of innate immune cellular activation. AIDS 2009, 23, 2255–2263, doi: 10.1097/QAD. 0b013e328331a4ce. Tsang J. Chain B.M. Miller R.F. Webb B.L. Barclay W. Towers G.J. Katz D.R. Noursadeghi M. HIV-1 infection of macrophages is dependent on evasion of innate immune cellular activation AIDS 2009 23 2255 2263 10.1097/QAD.0b013e328331a4ce.Open DOISearch in Google Scholar

Usui T., Meas S., Konnai S., Ohashi K., Onuma M.: Seroprevalence of bovine immunodeficiency virus and bovine leukemia virus in dairy and beef cattle in Hokkaido. J Vet Med Sci 2003, 65, 287–289, doi: 10.1292/jvms.65.287. Usui T. Meas S. Konnai S. Ohashi K. Onuma M. Seroprevalence of bovine immunodeficiency virus and bovine leukemia virus in dairy and beef cattle in Hokkaido J Vet Med Sci 2003 65 287 289 10.1292/jvms.65.287.Open DOISearch in Google Scholar

Van Der Maaten M.J., Boothe A.D., Seger C.L.: Isolation of a virus from cattle with persistent lymphocytosis. J Natl Cancer Inst 1972, 49, 1649–1657, doi: 10.1093/jnci/49.6.1649. Van Der Maaten M.J. Boothe A.D. Seger C.L. Isolation of a virus from cattle with persistent lymphocytosis J Natl Cancer Inst 1972 49 1649 1657 10.1093/jnci/49.6.1649.Open DOISearch in Google Scholar

Vanherwegen A.S., Eelen G., Ferreira G.B., Ghesquière B., Cook D.P., Nikolic T., Roep B., Carmeliet P., Telang S., Mathieu C., Gysemans C.: Vitamin D controls the capacity of human dendritic cells to induce functional regulatory T cells by regulation of glucose metabolism. J Steroid Biochem Mol Biol 2019, 187, 134–145, doi: 10.1016/j.jsbmb.2018.11.011. Vanherwegen A.S. Eelen G. Ferreira G.B. Ghesquière B. Cook D.P. Nikolic T. Roep B. Carmeliet P. Telang S. Mathieu C. Gysemans C. Vitamin D controls the capacity of human dendritic cells to induce functional regulatory T cells by regulation of glucose metabolism J Steroid Biochem Mol Biol 2019 187 134 145 10.1016/j.jsbmb.2018.11.011.Open DOISearch in Google Scholar

Weeks B.S.: The role of HIV-1 activated leukocyte adhesion mechanisms and matrix metalloproteinase secretion in AIDS pathogenesis. Int J Mol Med 1998, 1, 361–366, doi: 10.3892/ijmm.1.2.361. Weeks B.S. The role of HIV-1 activated leukocyte adhesion mechanisms and matrix metalloproteinase secretion in AIDS pathogenesis Int J Mol Med 1998 1 361 366 10.3892/ijmm.1.2.361.Open DOISearch in Google Scholar

Whetstone C.A., Suarez D.L., Miller J.M., Pesch B.A., Harp J.A.: Bovine lentivirus induces early transient B-cell proliferation in experimentally inoculated cattle and appears to be pantropic. J Virol 1997 71, 640–644, doi: 10.1128/jvi.71.1.640-644.1997. Whetstone C.A. Suarez D.L. Miller J.M. Pesch B.A. Harp J.A. Bovine lentivirus induces early transient B-cell proliferation in experimentally inoculated cattle and appears to be pantropic. J Virol 1997 71 640 644 10.1128/jvi.71.1.640-644.1997.Open DOISearch in Google Scholar

Wu J.Q., Sassé T.R., Wolkenstein G., Conceicao V., Saksena M.M., Soedjono M., Perera S.S., Wang B., Dwyer D.E., Saksena N.K.: Transcriptome analysis of primary monocytes shows global down-regulation of genetic networks in HIV viremic patients versus long-term non-progressors. Virology 2013, 435, 308–319, doi: 10.1016/j.virol.2012.10.026. Wu J.Q. Sassé T.R. Wolkenstein G. Conceicao V. Saksena M.M. Soedjono M. Perera S.S. Wang B. Dwyer D.E. Saksena N.K. Transcriptome analysis of primary monocytes shows global down-regulation of genetic networks in HIV viremic patients versus long-term non-progressors Virology 2013 435 308 319 10.1016/j.virol.2012.10.026.Open DOISearch in Google Scholar

Zhang S., Wood C., Xue W., Krukenberg S.M., Chen Q., Minocha H.C.: Immune suppression in calves with bovine immunodeficiency virus. Clin Diagnostic Lab Immunol 1997, 4, 232–235, doi: 10.1128/cdli.4.2.232-235.1997. Zhang S. Wood C. Xue W. Krukenberg S.M. Chen Q. Minocha H.C. Immune suppression in calves with bovine immunodeficiency virus Clin Diagnostic Lab Immunol 1997 4 232 235 10.1128/cdli.4.2.232-235.1997.Open DOISearch in Google Scholar