<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Swine DNA viruses have developed unique mechanisms for evasion of the host immune system, infection and DNA replication, and finally, construction and release of new viral particles. This article reviews four classes of DNA viruses affecting swine: porcine circoviruses, African swine fever virus, porcine parvoviruses, and pseudorabies virus. Porcine circoviruses belonging to the <italic>Circoviridae</italic> family are small single-stranded DNA viruses causing different diseases in swine including poly-weaning multisystemic wasting syndrome, porcine dermatitis and nephropathy syndrome, and porcine respiratory disease complex. African swine fever virus, the only member of the <italic>Asfivirus</italic> genus in the <italic>Asfarviridae</italic> family, is a large double-stranded DNA virus and for its propensity to cause high mortality, it is currently considered the most dangerous virus in the pig industry. Porcine parvoviruses are small single-stranded DNA viruses belonging to the <italic>Parvoviridae</italic> family that cause reproductive failure in pregnant gilts. Pseudorabies virus, or suid herpesvirus 1, is a large double-stranded DNA virus belonging to the <italic>Herpesviridae</italic> family and <italic>Alphaherpesvirinae</italic> subfamily. Recent findings including general as well as genetic classification, virus structure, clinical syndromes and the host immune system responses and vaccine protection are described for all four swine DNA virus classes.</p></abstract>

Swine DNA viruses have developed unique mechanisms for evasion of the host immune system, infection and DNA replication, and finally, construction and release of new viral particles. This article reviews four classes of DNA viruses affecting swine: porcine circoviruses, African swine fever virus, porcine parvoviruses, and pseudorabies virus. Porcine circoviruses belonging to the Circoviridae family are small single-stranded DNA viruses causing different diseases in swine including poly-weaning multisystemic wasting syndrome, porcine dermatitis and nephropathy syndrome, and porcine respiratory disease complex. African swine fever virus, the only member of the Asfivirus genus in the Asfarviridae family, is a large double-stranded DNA virus and for its propensity to cause high mortality, it is currently considered the most dangerous virus in the pig industry. Porcine parvoviruses are small single-stranded DNA viruses belonging to the Parvoviridae family that cause reproductive failure in pregnant gilts. Pseudorabies virus, or suid herpesvirus 1, is a large double-stranded DNA virus belonging to the Herpesviridae family and Alphaherpesvirinae subfamily. Recent findings including general as well as genetic classification, virus structure, clinical syndromes and the host immune system responses and vaccine protection are described for all four swine DNA virus classes.

The main DNA viruses significantly affecting pig livestock

Journal of Veterinary Research

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"The main DNA viruses significantly affecting pig livestock"}

Swine DNA viruses have developed unique mechanisms for evasion of the host immune system, infection and DNA replication, and finally, construction and release...

The main DNA viruses significantly affecting pig livestock

Article Category: Review Article

Publicado en línea: 29 dic 2020

Páginas: 15 - 25

Recibido: 28 may 2020

Aceptado: 03 dic 2020

DOI: https://doi.org/10.2478/jvetres-2021-0001

Palabras clave
DNA viruses, circoviruses, African swine fever virus, parvoviruses, pseudorabies virus

© 2021 C. Díaz et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Fig. 1

The main DNA viruses significantly affecting pig livestock

Article Category: Review Article

Publicado en línea: 29 dic 2020

Páginas: 15 - 25

Recibido: 28 may 2020

Aceptado: 03 dic 2020

DOI: https://doi.org/10.2478/jvetres-2021-0001

Palabras claveDNA viruses, circoviruses, African swine fever virus, parvoviruses, pseudorabies virus

© 2021 C. Díaz et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Fig. 1

Palabras clave
DNA viruses, circoviruses, African swine fever virus, parvoviruses, pseudorabies virus