<abstract xmlns="http://www.w3.org/1999/xhtml"><p>This paper describes a new combined impedance plethysmographic (IPG) and electrical bioimpedance spectroscopic (BIS) instrument and software that will allow noninvasive real-time measurement of segmental blood flow, intracellular, interstitial, and intravascular volume changes during various fluid management procedures. The impedance device can be operated either as a fixed frequency IPG for the quantification of segmental blood flow and hemodynamics or as a multi-frequency BIS for the recording of intracellular and extracellular resistances at 40 discrete input frequencies. The extracellular volume is then deconvoluted to obtain its intravascular and interstitial component volumes as functions of elapsed time. The purpose of this paper is to describe this instrumentation and to demonstrate the information that can be obtained by using it to monitor segmental compartment volume responses of a pig model during simulated hemorrhage and resuscitation. Such information may prove valuable in the diagnosis and management of rapid changes in the body fluid balance and various clinical treatments.</p></abstract>

This paper describes a new combined impedance plethysmographic (IPG) and electrical bioimpedance spectroscopic (BIS) instrument and software that will allow noninvasive real-time measurement of segmental blood flow, intracellular, interstitial, and intravascular volume changes during various fluid management procedures. The impedance device can be operated either as a fixed frequency IPG for the quantification of segmental blood flow and hemodynamics or as a multi-frequency BIS for the recording of intracellular and extracellular resistances at 40 discrete input frequencies. The extracellular volume is then deconvoluted to obtain its intravascular and interstitial component volumes as functions of elapsed time. The purpose of this paper is to describe this instrumentation and to demonstrate the information that can be obtained by using it to monitor segmental compartment volume responses of a pig model during simulated hemorrhage and resuscitation. Such information may prove valuable in the diagnosis and management of rapid changes in the body fluid balance and various clinical treatments.

Segmental intracellular, interstitial, and intravascular volume changes during simulated hemorrhage and resuscitation: A case study

Journal of Electrical Bioimpedance

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

This paper describes a new combined impedance plethysmographic (IPG) and electrical bioimpedance spectroscopic (BIS) instrument and software that will allow...

Segmental intracellular, interstitial, and intravascular volume changes during simulated hemorrhage and resuscitation: A case study

Publicado en línea: 20 ago 2019

Páginas: 40 - 46

Recibido: 01 feb 2019

DOI: https://doi.org/10.2478/joeb-2019-0006

Palabras clave
Bioimpedance, compartment volumes, hemorrhage, resuscitation

© 2019 Montgomery, Montgomery, Gerth, Bodo, Stewart, Loughry. published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Segmental intracellular, interstitial, and intravascular volume changes during simulated hemorrhage and resuscitation: A case study

Publicado en línea: 20 ago 2019

Páginas: 40 - 46

Recibido: 01 feb 2019

DOI: https://doi.org/10.2478/joeb-2019-0006

Palabras claveBioimpedance, compartment volumes, hemorrhage, resuscitation

© 2019 Montgomery, Montgomery, Gerth, Bodo, Stewart, Loughry. published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Palabras clave
Bioimpedance, compartment volumes, hemorrhage, resuscitation