<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Silicosis is one of the oldest occupational diseases, known since the time of Hippocrates, and the diagnosis can be established after a latency time of more than 10 years after exposure cessation. In some cases of chronic silicosis, the disease can progress slowly, evolving over several decades, but it can also evolve into massive pulmonary fibrosis, also known as accelerated silicosis. Furthermore, in extremely rare cases, the disease can present a rapid progression into acute silicosis or silicoproteinosis. The present article gives a deeper view into silicosis and secondary massive progressive pulmonary fibrosis, as well as the difficulties encountered in the management of such patients. We present two different but similar cases that underline the importance of a precise diagnosis, pointing out the long latent period after the exposure to silicon-dioxide, more than 15 years in both cases. This accelerated form of silicosis associated with massive pulmonary fibrosis progressed in 2 years into respiratory failure in both cases.</p></abstract>

Silicosis is one of the oldest occupational diseases, known since the time of Hippocrates, and the diagnosis can be established after a latency time of more than 10 years after exposure cessation. In some cases of chronic silicosis, the disease can progress slowly, evolving over several decades, but it can also evolve into massive pulmonary fibrosis, also known as accelerated silicosis. Furthermore, in extremely rare cases, the disease can present a rapid progression into acute silicosis or silicoproteinosis. The present article gives a deeper view into silicosis and secondary massive progressive pulmonary fibrosis, as well as the difficulties encountered in the management of such patients. We present two different but similar cases that underline the importance of a precise diagnosis, pointing out the long latent period after the exposure to silicon-dioxide, more than 15 years in both cases. This accelerated form of silicosis associated with massive pulmonary fibrosis progressed in 2 years into respiratory failure in both cases.

The Evolution of Silicosis into Massive Pulmonary Fibrosis — Case Series

Journal of Interdisciplinary Medicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"The Evolution of Silicosis into Massive Pulmonary Fibrosis \u2014 Case Series"}

Silicosis is one of the oldest occupational diseases, known since the time of Hippocrates, and the diagnosis can be established after a latency time of more...

The Evolution of Silicosis into Massive Pulmonary Fibrosis — Case Series

Publicado en línea: 19 dic 2018

Páginas: 45 - 49

Recibido: 21 dic 2017

Aceptado: 15 feb 2018

DOI: https://doi.org/10.2478/jim-2018-0006

Palabras clave
silicosis, massive pulmonary fibrosis, Caplan’s syndrome, large pulmonary mass

© 2018 Enikő Székely-Vass et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

The Evolution of Silicosis into Massive Pulmonary Fibrosis — Case Series

Publicado en línea: 19 dic 2018

Páginas: 45 - 49

Recibido: 21 dic 2017

Aceptado: 15 feb 2018

DOI: https://doi.org/10.2478/jim-2018-0006

Palabras clavesilicosis, massive pulmonary fibrosis, Caplan’s syndrome, large pulmonary mass

© 2018 Enikő Székely-Vass et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Palabras clave
silicosis, massive pulmonary fibrosis, Caplan’s syndrome, large pulmonary mass