<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Following the outbreak of the coronavirus disease 2019 (COVID-19) pandemic, design, development, validation, verification and implementation of diagnostic tests were actively addressed by a large number of diagnostic test manufacturers. This paper deals with the biases and sources of variation which influence the accuracy of diagnostic tests, including calculating and interpreting test characteristics, defining what is meant by test accuracy, understanding the basic study design for evaluating test accuracy, understanding the meaning of Sensitivity, Specificity, Positive Predictive Value and Negative Predictive Value, and evaluating them numerically, and the ROC curve (or Receiver Operating Characteristic ) and the Area under the Curve (AUC).</p>
</abstract>

Following the outbreak of the coronavirus disease 2019 (COVID-19) pandemic, design, development, validation, verification and implementation of diagnostic tests were actively addressed by a large number of diagnostic test manufacturers. This paper deals with the biases and sources of variation which influence the accuracy of diagnostic tests, including calculating and interpreting test characteristics, defining what is meant by test accuracy, understanding the basic study design for evaluating test accuracy, understanding the meaning of Sensitivity, Specificity, Positive Predictive Value and Negative Predictive Value, and evaluating them numerically, and the ROC curve (or Receiver Operating Characteristic ) and the Area under the Curve (AUC).

Accuracy of Diagnostic Tests

The Journal of Critical Care Medicine

This work is licensed under the Creative Commons Attribution 4.0 International License.

{"article-title":"Accuracy of Diagnostic Tests"}

Following the outbreak of the coronavirus disease 2019 (COVID-19) pandemic, design, development, validation, verification and implementation of diagnostic...

Accuracy of Diagnostic Tests

Article Category: Spotlight on...

Publicado en línea: 05 ago 2021

Páginas: 241 - 248

Recibido: 11 mar 2021

Aceptado: 27 jun 2021

DOI: https://doi.org/10.2478/jccm-2021-0022

Palabras clave
2019 (COVID-19) pandemic, diagnostic tests, ROC curve, Receiver Operating Characteristic

© 2021 Ario Santini, Adrian Man, Septimiu Voidăzan, published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Accuracy of Diagnostic Tests

Article Category: Spotlight on...

Publicado en línea: 05 ago 2021

Páginas: 241 - 248

Recibido: 11 mar 2021

Aceptado: 27 jun 2021

DOI: https://doi.org/10.2478/jccm-2021-0022

Palabras clave2019 (COVID-19) pandemic, diagnostic tests, ROC curve, Receiver Operating Characteristic

© 2021 Ario Santini, Adrian Man, Septimiu Voidăzan, published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Palabras clave
2019 (COVID-19) pandemic, diagnostic tests, ROC curve, Receiver Operating Characteristic