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Jung B, Rimmele T, Le Goff C, et al. Severe metabolic or mixed acidemia on intensive care unit admission: incidence, prognosis and administration of buffer therapy. a prospective, multiple-center study. Crit Care. 2011;15(5):R238.JungBRimmeleTLe GoffCet alSevere metabolic or mixed acidemia on intensive care unit admission: incidence, prognosis and administration of buffer therapy2011155R23810.1186/cc10487333478921995879Search in Google Scholar
Iberti TJ, Leibowitz AB, Papadakos PJ, Fischer EP. Low sensitivity of the anion gap as a screen to detect hyperlactatemia in critically ill patients. Crit Care Med. 1990;18:275-7.IbertiTJLeibowitzABPapadakosPJFischerEPLow sensitivity of the anion gap as a screen to detect hyperlactatemia in critically ill patients199018275–710.1097/00003246-199003000-000052302951Search in Google Scholar
Fall PJ, Szerlip HM. Lactic acidosis: from sour milk to septic shock. J Intensive Care Med. 2005;20:255–71.FallPJSzerlipHMLactic acidosis: from sour milk to septic shock200520255–7110.1177/088506660527864416145217Search in Google Scholar
Kraut JA, Madias NE. Lactic Acidosis. New Eng J Med. 2014;371: 2309–19.KrautJAMadiasNELactic Acidosis20143712309–1910.1056/NEJMra130948325494270Search in Google Scholar
Ferraris AM, Giuntini P, Gaetani GF. Serum lactic dehydrogenase as a prognostic tool for non-Hodgkin lymphomas. Blood. 1979;54:928–32.FerrarisAMGiuntiniPGaetaniGFSerum lactic dehydrogenase as a prognostic tool for non-Hodgkin lymphomas197954928–3210.1182/blood.V54.4.928.928Search in Google Scholar
Wilkinson JH. Lactate Dehydrogenase Isoenzymes. In Isoenzymes. New York: Springer. 1970, pp.134-203.WilkinsonJHLactate Dehydrogenase IsoenzymesInNew YorkSpringer1970pp13420310.1007/978-1-4899-6834-0Search in Google Scholar
Warburg O. On the origin of cancer cells. Science. 1956;123:309–14.WarburgOOn the origin of cancer cells1956123309–1410.1126/science.123.3191.30913298683Search in Google Scholar
Koppenol WH, Bounds PL, Dang CV. Otto Warburg’s contributions to current concepts of cancer metabolism. Nat Rev Cancer. 2011;11:325–37.KoppenolWHBoundsPLDangCVOtto Warburg’s contributions to current concepts of cancer metabolism201111325–3710.1038/nrc303821508971Search in Google Scholar
Ahuja P, Zhao P, Angelis E, et al. Myc controls transcriptional regulation of cardiac metabolism and mitochondrial biogenesis in response to pathological stress in mice. J Clin Invest. 2010;120:1494–505.AhujaPZhaoPAngelisEet alMyc controls transcriptional regulation of cardiac metabolism and mitochondrial biogenesis in response to pathological stress in mice20101201494–50510.1172/JCI38331286090120364083Search in Google Scholar
Dang CV. c-Myc target genes involved in cell growth, apoptosis, and metabolism. Mol Cell Biol. 1999;19:1–11.DangCVc-Myc target genes involved in cell growth, apoptosis, and metabolism1999191–1110.1128/MCB.19.1.1838609858526Search in Google Scholar
Yun J, Rago C, Cheong I, et al. Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells. Science. 2009;325:1555–9.YunJRagoCCheongIet alGlucose deprivation contributes to the development of KRAS pathway mutations in tumor cells20093251555–910.1126/science.1174229282037419661383Search in Google Scholar
Ramanathan A, Wang C, Schreiber SL. Perturbational profiling of a cell-line model of tumorigenesis by using metabolic measurements. Proc Natl Acad Sci USA. 2005;102:5992–7.RamanathanAWangCSchreiberSLPerturbational profiling of a cell-line model of tumorigenesis by using metabolic measurements20051025992–710.1073/pnas.0502267102108796115840712Search in Google Scholar
Elstrom RL, Bauer DE, Buzzai M, et al. Akt stimulates aerobic glycolysis in cancer cells. Cancer Re.s 2004;64:3892–9.ElstromRLBauerDEBuzzaiMet alAkt stimulates aerobic glycolysis in cancer cells2004643892–910.1158/0008-5472.CAN-03-290415172999Search in Google Scholar
Robey RB, Hay N. Is Akt the ‘Warburg kinase’?-Akt-energy metabolism interactions and oncogenesis. Semin Cancer Biol. 2009;19:25–31.RobeyRBHayNIs Akt the ‘Warburg kinase’?-Akt-energy metabolism interactions and oncogenesis20091925–3110.1016/j.semcancer.2008.11.010281445319130886Search in Google Scholar
Deprez J, Vertommen D, Alessi DR, Hue L, Rider MH. Phosphorylation and activation of heart 6-phosphofructo-2-kinase by protein kinase B and other protein kinases of the insulin signaling cascades. J Biol Chem. 1997;272:17269–75.DeprezJVertommenDAlessiDRHueLRiderMHPhosphorylation and activation of heart 6-phosphofructo-2-kinase by protein kinase B and other protein kinases of the insulin signaling cascades199727217269–7510.1074/jbc.272.28.172699211863Search in Google Scholar
Matoba S, Kang JG, Patino WD, et al. p53 regulates mitochondrial respiration. Science. 2006;312:1650–3.MatobaSKangJGPatinoWDet alp53 regulates mitochondrial respiration20063121650–310.1126/science.112686316728594Search in Google Scholar
Vousden KH, Ryan KM. p53 and metabolism. Nat Rev Cancer. 2009;9:691–700.VousdenKHRyanKMp53 and metabolism20099691–70010.1038/nrc271519759539Search in Google Scholar
Zhang C, Liu J, Liang Y, et al. Tumour-associated mutant p53 drives the Warburg effect. Nat. Commun. 2013;4,2935.ZhangCLiuJLiangYet alTumour-associated mutant p53 drives the Warburg effect. Nat20134293510.1038/ncomms3935Search in Google Scholar
Kruse O, Grunnet N, Barfod C. Blood lactate as a predictor for in-hospital mortality in patients admitted acutely to hospital: a systematic review. Scand J Trauma Resusc Emerg Med. 2001;19:74.KruseOGrunnetNBarfodCBlood lactate as a predictor for in-hospital mortality in patients admitted acutely to hospital: a systematic review2001197410.1186/1757-7241-19-74329283822202128Search in Google Scholar
Bloom BM, Grundlingh J, Bestwick JP, Harris T. The role of venous blood gas in the emergency department: a systematic review and meta-analysis. Eur J Emerg Med. 2014;21:81–8.BloomBMGrundlinghJBestwickJPHarrisTThe role of venous blood gas in the emergency department: a systematic review and meta-analysis20142181–810.1097/MEJ.0b013e32836437cf23903783Search in Google Scholar
Réminiac F, Saint-Etienne C, Runge I, et al. Are central venous lactate and arterial lactate interchangeable? A human retrospective study. Anesth Analg. 2012;115:605–10.RéminiacFSaint-EtienneCRungeIet alAre central venous lactate and arterial lactate interchangeable? A human retrospective study2012115605–1010.1213/ANE.0b013e31825e703e22745117Search in Google Scholar
Vitin AA, Azamfirei L, Tomescu D, Lang JD. Perioperative Management of Lactic Acidosis in End-Stage Liver Disease Patient. J Crit Care Med (Targu Mures). 2017;3:55–62.VitinAAAzamfireiLTomescuDLangJDPerioperative Management of Lactic Acidosis in End-Stage Liver Disease Patient2017355–6210.1515/jccm-2017-0014576991829967872Search in Google Scholar
del Portal DA, Shofer F, Mikkelsen ME, et al. Emergency department lactate is associated with mortality in older adults admitted with and without infections. Acad Emerg Med. 2010;17:260–8.del PortalDAShoferFMikkelsenMEet alEmergency department lactate is associated with mortality in older adults admitted with and without infections201017260–810.1111/j.1553-2712.2010.00681.x20370758Search in Google Scholar
Juneja D, Singh O, Dang R. Admission hyperlactatemia: causes, incidence, and impact on outcome of patients admitted in a general medical intensive care unit. J Crit Care. 2011;26:316–20.JunejaDSinghODangRAdmission hyperlactatemia: causes, incidence, and impact on outcome of patients admitted in a general medical intensive care unit201126316–2010.1016/j.jcrc.2010.11.00921255970Search in Google Scholar