This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.
Bailey, L. (1955). The epidemiology and control of Nosema disease of the honey-bee. Annals of Applied Biology, 43(3), 379–389. https://doi.org/10.1111/j.1744-7348.1955.tb02488.xBaileyL.1955The epidemiology and control of Nosema disease of the honey-bee433379389https://doi.org/10.1111/j.1744-7348.1955.tb02488.x10.1111/j.1744-7348.1955.tb02488.xSearch in Google Scholar
Canadian National Bee Health Survey. (2017). Retrieved on 26 March 2019 from: https://www.gprc.ab.ca/doc.php?d=2017NHBHS2017Retrieved on 26 March 2019 from: https://www.gprc.ab.ca/doc.php?d=2017NHBHSSearch in Google Scholar
Cantwell, G. E. (1970). Standard methods for counting Nosema spores. American Bee Journal, 110(6), 52–54.CantwellG. E.1970Standard methods for counting Nosema spores11065254Search in Google Scholar
Chen, Y., Evans, J. D., Smith, B., & Pettis, J. S. (2008). Nosema ceranae is a long-present and wide-spread microsporidian infection of the European honey bee (Apis mellifera) in the United States. Journal of Invertebrate Pathology, 97(2), 186–188. https://doi.org/10.1016/j.jip.2007.07.010ChenY.EvansJ. D.SmithB.PettisJ. S.2008Nosema ceranae is a long-present and wide-spread microsporidian infection of the European honey bee (Apis mellifera) in the United States972186188https://doi.org/10.1016/j.jip.2007.07.01010.1016/j.jip.2007.07.01017880997Search in Google Scholar
Copley, T. R., Chen, H., Giovenazzo, P., Houle, E., Jabaji, S. H. (2012). Prevalence and seasonality of Nosema species in Quebec honey bees. Canadian Entomologist, 144(4), 577–588. https://doi.org/10.4039/tce.2012.46CopleyT. R.ChenH.GiovenazzoP.HouleE.JabajiS. H.2012Prevalence and seasonality of Nosema species in Quebec honey bees1444577588https://doi.org/10.4039/tce.2012.4610.4039/tce.2012.46Search in Google Scholar
Emsen, B., Guzman-Novoa, E., Md Hamiduzzaman, M., Eccles, L., Lacey, B., Ruiz-Perez, R. A., Nasr, M. (2016). Higher prevalence and loads of Nosema ceranae than Nosema apis infections in Canadian honey bee colonies. Parasitology Research, 115(1), 175–181. https://doi.org/10.1007/s00436-015-4733-3EmsenB.Guzman-NovoaE.Md HamiduzzamanM.EcclesL.LaceyB.Ruiz-PerezR. A.NasrM.2016Higher prevalence and loads of Nosema ceranae than Nosema apis infections in Canadian honey bee colonies1151175181https://doi.org/10.1007/s00436-015-4733-310.1007/s00436-015-4733-326358102Search in Google Scholar
Ferland, J., Kempers, M., Kennedy, K., Kozak, P., Lafrenière, R., Maund, C., … Wilson, G. (2019). Canadian Association of Professional Apiculturists statement on honey bee wintering losses in Canada. Retrieved on 22 January 2020 from: http://www.capabees.com/shared/2018-2019-CAPA-Statement-on-Colony-Losses.pdfFerlandJ.KempersM.KennedyK.KozakP.LafrenièreR.MaundC.WilsonG.2019Retrieved on 22 January 2020 from: http://www.capabees.com/shared/2018-2019-CAPA-Statement-on-Colony-Losses.pdfSearch in Google Scholar
Fries, I. (2010). Nosema ceranae in European honey bees (Apis mellifera). Journal of Invertebrate Pathology, 103(1), S73–S79. https://doi.org/10.1016/j.jip.2009.06.017FriesI.2010Nosema ceranae in European honey bees (Apis mellifera)1031S73S79https://doi.org/10.1016/j.jip.2009.06.01710.1016/j.jip.2009.06.01719909977Search in Google Scholar
Fries, I., Chauzat, M.-P., Chen, Y.-P., Doublet, V., Genersch, E., Gisder, S., ... Williams, G. R. (2013). Standard methods for Nosema research. Journal of Apicultural Research, 52(1), 1–28. https://doi.org/10.3896/IBRA.1.52.1.14FriesI.ChauzatM.-P.ChenY.-P.DoubletV.GenerschE.GisderS.WilliamsG. R.2013Standard methods for Nosema research521128https://doi.org/10.3896/IBRA.1.52.1.1410.3896/IBRA.1.52.1.14Search in Google Scholar
Frottin, F., Bienvenut, W. V., Bignon, J., Jacquet, E., Jacome, A. S. V., van Dorsselaer, A., … Giglione, C. (2016). MetAP1 and MetAP2 drive cell selectivity for a potent anti-cancer agent in synergy, by controlling glutathione redox state. Oncotarget, 7(39), 63306–63323. https://doi.org/10.18632/oncotarget.11216FrottinF.BienvenutW. V.BignonJ.JacquetE.JacomeA. S. V.van DorsselaerA.GiglioneC.2016MetAP1 and MetAP2 drive cell selectivity for a potent anti-cancer agent in synergy, by controlling glutathione redox state7396330663323https://doi.org/10.18632/oncotarget.1121610.18632/oncotarget.11216532536527542228Search in Google Scholar
Gisder, S., & Genersch, E. (2013). Molecular differentiation of Nosema apis and Nosema ceranae based on species-specific sequences differences in a protein coding gene. Journal of Invertebrate Pathology, 113(1), 1–6. https://doi.org/10.1016/j.jip.2013.01.004GisderS.GenerschE.2013Molecular differentiation of Nosema apis and Nosema ceranae based on species-specific sequences differences in a protein coding gene113116https://doi.org/10.1016/j.jip.2013.01.00410.1016/j.jip.2013.01.00423352902Search in Google Scholar
Guzman-Novoa, E., Eccles, L., Calvete, Y., McGowan, J., Kelly, P. G., Correa-Benitez, A. (2010). Varroa destructor is the main culprit for the death and reduced populations of overwintered honey bee (Apis mellifera) colonies in Ontario, Canada. Apidologie, 41(4), 443–450. https://doi.org/10.1051/apido/2009076Guzman-NovoaE.EcclesL.CalveteY.McGowanJ.KellyP. G.Correa-BenitezA.2010Varroa destructor is the main culprit for the death and reduced populations of overwintered honey bee (Apis mellifera) colonies in Ontario, Canada414443450https://doi.org/10.1051/apido/200907610.1051/apido/2009076Search in Google Scholar
Hamiduzzaman, M. M., Guzman-Novoa, E., & Goodwin, P. H. (2010). A multiplex PCR assay to diagnose and quantify Nosema infections in honey bees (Apis mellifera). Journal of Invertebrate Pathology, 105(2), 151–155. https://doi.org/10.1016/j.jip.2010.06.001HamiduzzamanM. M.Guzman-NovoaE.GoodwinP. H.2010A multiplex PCR assay to diagnose and quantify Nosema infections in honey bees (Apis mellifera)1052151155https://doi.org/10.1016/j.jip.2010.06.00110.1016/j.jip.2010.06.00120570679Search in Google Scholar
Higes, M., Martín-Hernández, R., Botías, C., Garrido Bailón, E., González-Porto, A. V., Barrios, L., ... Meana, A. (2008). How natural infection by Nosema ceranae causes honeybee colony collapse. Environmental Microbiology, 10(10), 2659–2669. https://doi.org/10.1111/j.1462-2920.2008.01687.xHigesM.Martín-HernándezR.BotíasC.Garrido BailónE.González-PortoA. V.BarriosL.MeanaA.2008How natural infection by Nosema ceranae causes honeybee colony collapse101026592669https://doi.org/10.1111/j.1462-2920.2008.01687.x10.1111/j.1462-2920.2008.01687.x18647336Search in Google Scholar
Higes, M., Martín-Hernández, R., & Meana, A. (2010). Nosema ceranae in Europe: an emergent type C nosemosis. Apidologie, 41(3), 375–392. https://doi.org/10.1051/apido/2010019HigesM.Martín-HernándezR.MeanaA.2010Nosema ceranae in Europe: an emergent type C nosemosis413375392https://doi.org/10.1051/apido/201001910.1051/apido/2010019Search in Google Scholar
Higes, M., Meana, A., Bartolomé, C., Botías, C., Martín-Hernández, R. (2013). Nosema ceranae (Microsporidia), a controversial 21st century honey bee pathogen. Environmental Microbiology Reports, 5(1), 17–29. https://doi.org/10.1111/1758-2229HigesM.MeanaA.BartoloméC.BotíasC.Martín-HernándezR.2013Nosema ceranae (Microsporidia), a controversial 21st century honey bee pathogen511729https://doi.org/10.1111/1758-222910.1111/1758-2229.1202423757127Search in Google Scholar
Holt, H. L., & Grozinger, C. M. (2016). Approaches and challenges to managing Nosema (Microspora: Nosematidae) parasites in honey bee (Hymenoptera: Apidae) colonies. Journal of Economic Entomology, 109(4), 1487–1503. https://doi.org/10.1093/jee/tow103HoltH. L.GrozingerC. M.2016Approaches and challenges to managing Nosema (Microspora: Nosematidae) parasites in honey bee (Hymenoptera: Apidae) colonies109414871503https://doi.org/10.1093/jee/tow10310.1093/jee/tow10327340190Search in Google Scholar
Huang, W.-F., Solter, L. F., Yau, P. M., & Imai, B. S. (2013). Nosema ceranae escapes fumagillin control in honey bees. PLoS Pathology, 9(3), 1–9. https://doi.org/10.1371/journal.ppat.1003185HuangW.-F.SolterL. F.YauP. M.ImaiB. S.2013Nosema ceranae escapes fumagillin control in honey bees9319https://doi.org/10.1371/journal.ppat.100318510.1371/journal.ppat.1003185359133323505365Search in Google Scholar
Human, H., Brodschneider, R., Dietemann, V., Dively, G., Ellis, J. D., Forsgren, E., … Zheng, H.-Q. (2013). Miscellaneous standard methods for Apis mellifera research. Journal of Apicultural Research, 52(4), 1–53. https://doi.org/10.3896/IBRA.1.52.4.10HumanH.BrodschneiderR.DietemannV.DivelyG.EllisJ. D.ForsgrenE.ZhengH.-Q.2013Miscellaneous standard methods for Apis mellifera research524153https://doi.org/10.3896/IBRA.1.52.4.1010.3896/IBRA.1.52.4.10Search in Google Scholar
Johnson, R. M., Dahlgren, L., Siegfried, B. D., & Ellis, M. (2013). Acaracide, fungicide and drug interactions in honey bees (Apis mellifera). PLoS ONE, 8(1), https://doi.org/10.1371/journal.pone.0054092JohnsonR. M.DahlgrenL.SiegfriedB. D.EllisM.2013Acaracide, fungicide and drug interactions in honey bees (Apis mellifera)81https://doi.org/10.1371/journal.pone.005409210.1371/journal.pone.0054092355850223382869Search in Google Scholar
Klee, J., Besana, A. M., Genersch, E., Gisder, S., Nanetti, A., Tam, D. Q., … Paxton, R. J. (2007). Widespread dispersal of the microsporidian Nosema ceranae, an emergent pathogen of the western honey bee, Apis mellifera. Journal of Invertebrate Pathology, 96(1), 1–10. https://doi.org/10.1016/j.jip.2007.02.014KleeJ.BesanaA. M.GenerschE.GisderS.NanettiA.TamD. Q.PaxtonR. J.2007Widespread dispersal of the microsporidian Nosema ceranae, an emergent pathogen of the western honey bee, Apis mellifera961110https://doi.org/10.1016/j.jip.2007.02.01410.1016/j.jip.2007.02.01417428493Search in Google Scholar
Martín-Hernández, R., Bartolomé, C., Chejanovsky, N., Le Conte, Y., Dalmon, A., Dussaubat, C., … Higes, M. (2012). Nosema ceranae in Apis mellifera: a 12 years postdetection perspective. Environmental Microbiology, 20(4), 1302–1329. https://doi.org/10.1111/1462-2920.14103Martín-HernándezR.BartoloméC.ChejanovskyN.Le ConteY.DalmonA.DussaubatC.HigesM.2012Nosema ceranae in Apis mellifera: a 12 years postdetection perspective20413021329https://doi.org/10.1111/1462-2920.1410310.1111/1462-2920.1410329575513Search in Google Scholar
Meana, A., Martín-Hernández, R., & Higes, M. (2010). The reliability of spore counts to diagnose Nosema ceranae infections in honey bees. Journal of Apicultural Research, 49(2), 212–214. https://doi.org/10.3896/IBRA.1.49.2.12MeanaA.Martín-HernándezR.HigesM.2010The reliability of spore counts to diagnose Nosema ceranae infections in honey bees492212214https://doi.org/10.3896/IBRA.1.49.2.1210.3896/IBRA.1.49.2.12Search in Google Scholar
Milbrath, M. O., van Tran, T., Huang, W.-F., Solter, L. F., Tarpy, D. R., Lawrence, F., Huang, Z. F. (2015). Comparative virulence and competition between Nosema apis and Nosema ceranae in honey bees (Apis mellifera). Journal of Invertebrate Pathology, 125, 9–15. https://doi.org/10.1016/j.jip.2014.12.006MilbrathM. O.van TranT.HuangW.-F.SolterL. F.TarpyD. R.LawrenceF.HuangZ. F.2015Comparative virulence and competition between Nosema apis and Nosema ceranae in honey bees (Apis mellifera)125915https://doi.org/10.1016/j.jip.2014.12.00610.1016/j.jip.2014.12.00625527406Search in Google Scholar
Minitab Inc. (2018). Version 18. State College, PA.Minitab Inc2018State College, PASearch in Google Scholar
Paxton, R. J., Klee, J., Korpela, S., & Fries, I. (2007). Nosema ceranae has infected Apis mellifera in Europe since at least 1998 and may be more virulent than Nosema apis. Apidologie, 38(6), 558–565. https://doi.org/10.1051/apido:2007037PaxtonR. J.KleeJ.KorpelaS.FriesI.2007Nosema ceranae has infected Apis mellifera in Europe since at least 1998 and may be more virulent than Nosema apis386558565https://doi.org/10.1051/apido:200703710.1051/apido:2007037Search in Google Scholar
Retschnig, G., Williams, G. R., Schneeberger, A., & Neumann, P. (2017). Cold ambient temperature promotes Nosema spp. intensity in honey bees (Apis mellifera). Insects, 8(1), https://doi.org/10.3390/insects8010020RetschnigG.WilliamsG. R.SchneebergerA.NeumannP.2017Cold ambient temperature promotes Nosema spp. intensity in honey bees (Apis mellifera)81https://doi.org/10.3390/insects801002010.3390/insects8010020537194828208761Search in Google Scholar
Stevanovic, J., Simeunovic, P., Gajic, B., Lakic, N., Radovic, D., Fries, I., Stanimirovic, Z. (2013). Characteristics of Nosema ceranae infection in Serbian honey bee colonies. Apidologie, 44(5), 522–536. https://doi.org/10.1007/s13592-013-0203-zStevanovicJ.SimeunovicP.GajicB.LakicN.RadovicD.FriesI.StanimirovicZ.2013Characteristics of Nosema ceranae infection in Serbian honey bee colonies445522536https://doi.org/10.1007/s13592-013-0203-z10.1007/s13592-013-0203-zSearch in Google Scholar
Traver, B. E., Williams, M. R., & Fell, R. D. (2012). Comparison of within hive sampling and seasonal activity of Nosema ceranae in honey bee colonies. Journal of Invertebrate Pathology, 109(2), 187–193. https://doi.org/10.1016/j.jip.2011.11.001TraverB. E.WilliamsM. R.FellR. D.2012Comparison of within hive sampling and seasonal activity of Nosema ceranae in honey bee colonies1092187193https://doi.org/10.1016/j.jip.2011.11.00110.1016/j.jip.2011.11.00122085836Search in Google Scholar
van den Heever, J. P., Thompson, T. S., Otto, S. J., Curtis, J. M., Ibrahim, A., Pernal, S. F. (2016). Evaluation of Fumagilin-B® and other potential alternative chemotherapies against Nosema ceranae-infected honey-bees (Apis mellifera) in cage trial assays. Apidologie, 47, 617–630. https://doi.org/10.1007/s13592-015-0409-3van den HeeverJ. P.ThompsonT. S.OttoS. J.CurtisJ. M.IbrahimA.PernalS. F.2016Evaluation of Fumagilin-B® and other potential alternative chemotherapies against Nosema ceranae-infected honey-bees (Apis mellifera) in cage trial assays47617630https://doi.org/10.1007/s13592-015-0409-310.1007/s13592-015-0409-3Search in Google Scholar
Williams, G. R., Sampson, M. A, Shutler, D., Rogers, R. L. (2008). Does fumagillin control the recently detected invasive parasite Nosema ceranae in western honey bees (Apis mellifera)? Journal of Invertebrate Pathology, 99(3), 342–344. https://doi.org/10.1016/j.jip.2008.04.005WilliamsG. R.SampsonM. AShutlerD.RogersR. L.2008Does fumagillin control the recently detected invasive parasite Nosema ceranae in western honey bees (Apis mellifera)?993342344https://doi.org/10.1016/j.jip.2008.04.00510.1016/j.jip.2008.04.00518550078Search in Google Scholar
Williams, G. R., Shutler, D., Burgher-MacLellan, K. L., Rogers, R. E. L. (2014). Infra-population and -community dynamics of the parasites Nosema apis and Nosema ceranae, and consequences for honey bee (Apis mellifera) hosts. PLoS ONE, 9(7), https://doi.org/10.1371/journal.pone.0099465WilliamsG. R.ShutlerD.Burgher-MacLellanK. L.RogersR. E. L.2014Infra-population and -community dynamics of the parasites Nosema apis and Nosema ceranae, and consequences for honey bee (Apis mellifera) hosts97https://doi.org/10.1371/journal.pone.009946510.1371/journal.pone.0099465407928324987989Search in Google Scholar
Williams, G. R., Shutler, D., Little, C. M., Burgher-Maclellan, K. L., Rogers, R. E. L. (2011). The microsporidian Nosema ceranae, the antibiotic Fumagilin-B®, and western honey bee (Apis mellifera) colony strength. Apidologie, 42, 15–22. https://doi.org/10.1051/api-do/2010030WilliamsG. R.ShutlerD.LittleC. M.Burgher-MaclellanK. L.RogersR. E. L.2011The microsporidian Nosema ceranae, the antibiotic Fumagilin-B®, and western honey bee (Apis mellifera) colony strength421522https://doi.org/10.1051/api-do/201003010.1051/apido/2010030Search in Google Scholar
Zhang, Y., Yeh, J. R., Mara, A., Ju, R., Hines, J. F., Cirone, P., Griesbach, H. L., … Crews, C. M. (2006). A chemical and genetic approach to the mode of action of fumagillin. Chemistry Biology, 13(9), 1001–1009. https://doi.org/10.1016/j.chembiol.2006.07.010ZhangY.YehJ. R.MaraA.JuR.HinesJ. F.CironeP.GriesbachH. L.CrewsC. M.2006A chemical and genetic approach to the mode of action of fumagillin13910011009https://doi.org/10.1016/j.chembiol.2006.07.01010.1016/j.chembiol.2006.07.010258336916984890Search in Google Scholar