<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Interstitial lung disease is a generic term encompassing a wide range of unrelated conditions that have in common a tendency to cause shortness of breath and/or cough associated with bilateral abnormal opacity of various types on conventional chest X-rays or high-resolution computed tomography scans, symptoms including dyspnea, wheezing, cough, and/or sputum production. This study aimed to show that cigarette smoke is a powerful inducer of inflammation and the cause-effect relationship between cigarette smoking and interstitial diseases – respiratory bronchiolitis-associated interstitial lung disease (RB-ILD) and desquamative interstitial pneumonia (DIP). We bring to your attention the cases of two patients, heavy smokers with HRCT images suggestive for RB-ILD and DIP. The patients present to the on-call room with dry cough, exertional dyspnea and receive corticosteroid treatment with the recommendation to cease smoking. An approach would be to target high-risk populations, such as older adults with a history of smoking for early diagnosis of parenchymal lung diseases (e.g. ILD and chronic obstructive pulmonary disease) or lung cancer.</p>
</abstract>

Interstitial lung disease is a generic term encompassing a wide range of unrelated conditions that have in common a tendency to cause shortness of breath and/or cough associated with bilateral abnormal opacity of various types on conventional chest X-rays or high-resolution computed tomography scans, symptoms including dyspnea, wheezing, cough, and/or sputum production. This study aimed to show that cigarette smoke is a powerful inducer of inflammation and the cause-effect relationship between cigarette smoking and interstitial diseases – respiratory bronchiolitis-associated interstitial lung disease (RB-ILD) and desquamative interstitial pneumonia (DIP). We bring to your attention the cases of two patients, heavy smokers with HRCT images suggestive for RB-ILD and DIP. The patients present to the on-call room with dry cough, exertional dyspnea and receive corticosteroid treatment with the recommendation to cease smoking. An approach would be to target high-risk populations, such as older adults with a history of smoking for early diagnosis of parenchymal lung diseases (e.g. ILD and chronic obstructive pulmonary disease) or lung cancer.

Perspectives in Smoking Related Interstitial Lung Diseases

“Carol Davila” University of Medicine and Pharmacy

Internal Medicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Perspectives in Smoking Related Interstitial Lung Diseases"}

Interstitial lung disease is a generic term encompassing a wide range of unrelated conditions that have in common a tendency to cause shortness of breath...

Perspectives in Smoking Related Interstitial Lung Diseases

Publicado en línea: 12 jun 2024

Páginas: 111 - 123

DOI: https://doi.org/10.2478/inmed-2024-0293

Palabras clave
smoking, respiratory bronchiolitis-associated interstitial lung disease, desquamative interstitial pneumonia, corticosteroid therapy

© 2024 Ancuţa Constantin et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Perspectives in Smoking Related Interstitial Lung Diseases

Publicado en línea: 12 jun 2024

Páginas: 111 - 123

DOI: https://doi.org/10.2478/inmed-2024-0293

Palabras clavesmoking, respiratory bronchiolitis-associated interstitial lung disease, desquamative interstitial pneumonia, corticosteroid therapy

© 2024 Ancuţa Constantin et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Palabras clave
smoking, respiratory bronchiolitis-associated interstitial lung disease, desquamative interstitial pneumonia, corticosteroid therapy