[
Anguiano B, Rojas-Huidobro R, Delgado G, Aceves C. Has the mammary gland a protective mechanism against overexposure to triiodothyronine during the peripartum period? The prolactin pulse down-regulates mam-mary type I deiodinase responsiveness to norepinephrine. J Endocrinol 183, 267–277, 2004.10.1677/joe.1.05711
]Search in Google Scholar
[
Antonini D, Sibilio A, Dentice M, Missero C. An intimate relationship between thyroid hormone and skin: regulation of gene expression. Front Endocrinol (Lausanne) 4, 104, 2013.10.3389/fendo.2013.00104
]Search in Google Scholar
[
Aranda A, Pascual A. Nuclear hormone receptors and gene expression. Physiol Rev 81, 1269–1304, 2001.10.1152/physrev.2001.81.3.1269
]Search in Google Scholar
[
Aranda A, Martinez-Iglesias O, Ruiz-Llorente L, Garcia-Carpizo V, Zambrano A. Thyroid receptor: roles in cancer. Trends Endocrinol Metab 20, 318–324, 2009.10.1016/j.tem.2009.03.011
]Search in Google Scholar
[
Aranda A, Alonso-Merino E, Zambrano A. Receptors of thyroid hormones. Pediatr Endocrinol Rev 11, 2–13, 2013.
]Search in Google Scholar
[
Aranda A. MicroRNAs and thyroid hormone action. Mol Cell Endocrinol 525, 111175, 2021.10.1016/j.mce.2021.111175
]Search in Google Scholar
[
Bahouth SW. Thyroid hormones transcriptionally regulate the beta 1-adrenergic receptor gene in cultured ventricular myocytes. J Biol Chem 266, 15863–15869, 1991.10.1016/S0021-9258(18)98488-7
]Search in Google Scholar
[
Baker ME, Vaughn DA, Fanestil DD. Inhibition by protease inhibitors of binding of adrenal and sex steroid hormones. J Supramol Struct 9, 421–426, 1978.10.1002/jss.40009031285807
]Search in Google Scholar
[
Barettino D, Vivanco Ruiz MM, Stunnenberg HG. Characterization of the ligand-dependent transactivation domain of thyroid hormone receptor. EMBO J 13, 3039–3049, 1994.10.1002/j.1460-2075.1994.tb06603.x3951948039499
]Search in Google Scholar
[
Barsano CP, Iqbal Z, Pullen GL, Munoz BE, Singh SP. Tissue-specific differences in the compartmentalization of rat nuclear triiodothyronine receptors. Acta Endocrinol (Copenh) 122, 181–190, 1990.10.1530/acta.0.12201812316309
]Search in Google Scholar
[
Basu G, Mohapatra A. Interactions between thyroid disorders and kidney disease. Indian J Endocrinol Metab 2, 204–213, 2012.10.4103/2230-8210.93737331373722470856
]Search in Google Scholar
[
Beber EH, Capelo LP, Fonseca TL, Costa CC, Lotfi CF, Scanlan TS, Gouveia CH. The thyroid hormone receptor (TR) beta-selective agonist GC-1 inhibits proliferation but induces differentiation and TR beta mRNA expression in mouse and rat osteoblast-like cells. Calcif Tissue Int 84, 324–333, 2009.10.1007/s00223-009-9230-1
]Search in Google Scholar
[
Benbrook D, Pfahl M. A novel thyroid hormone receptor encoded by a cDNA clone from a human testis library. Science 238(4828), 788–791, 1987.10.1126/science.3672126
]Search in Google Scholar
[
Bernal J, Nunez J. Thyroid hormones and brain development. Eur J Endocrinol 133, 390–398, 1995.10.1530/eje.0.1330390
]Search in Google Scholar
[
Bernal J. Action of thyroid hormone in brain. J Endocrinol Invest 25, 268–288, 2002.10.1007/BF03344003
]Search in Google Scholar
[
Bernal J. Thyroid hormone receptors in brain development and function. Nat Clin Pract Endocrinol Metab 3, 249–259, 2007.10.1038/ncpendmet0424
]Search in Google Scholar
[
Berry MJ, Kates AL, Larsen PR. Thyroid hormone regulates type I deiodinase messenger RNA in rat liver. Mol Endocrinol 4, 743–748, 1990.10.1210/mend-4-5-743
]Search in Google Scholar
[
Bloise FF, Cordeiro A, Ortiga-Carvalho TM. Role of thyroid hormone in skeletal muscle physiology. J Endocrinol 236, R57–R68, 2018.10.1530/JOE-16-0611
]Search in Google Scholar
[
Brent GA, Larsen PR, Harney JW, Koenig RJ, Moore DD. Functional characterization of the rat growth hormone promoter elements required for induction by thyroid hormone with and without a co-transfected beta type thyroid hormone receptor. J Biol Chem 264, 178–182, 1989.10.1016/S0021-9258(17)31240-1
]Search in Google Scholar
[
Brtko J, Knopp J, DeGroot LJ. Physiochemical factors influencing the stability of solubilized liver nuclear receptor-3,5,3’-triiodothyronine complex in vitro. Endocrinol Exp 21, 251–256, 1987.
]Search in Google Scholar
[
Brtko J, Knopp J. Binding parameters of rat liver nuclear receptors for T3 after partial hepatectomy or bilateral adrenalectomy and serum T4 and T3 levels. Endocr Exper 22, 211–220, 1988.
]Search in Google Scholar
[
Brtko J, Ichikawa K, DeGroot LJ. Rat liver nuclear receptors for thyroid hormone: Binding characteristics after stabilization and storage. Folia Biologica (Praha) 39, 69–77, 1992a.
]Search in Google Scholar
[
Brtko J, Filipcik P, Knopp J, Sedlakova V, Rauova L. Thyroid hormone responsiveness of the L1210 murine leukemia cell line. Acta Endocrinol (Copenh) 126, 374–377, 1992b.10.1530/acta.0.1260374
]Search in Google Scholar
[
Brtko J, Knopp J, Baker ME. Inhibition of 3,5,3’-triiodothyronine binding to its receptor in rat liver by protease inhibitors and substrates. Mol Cell Endocrinol 93, 81–86, 1993.10.1016/0303-7207(93)90142-7
]Search in Google Scholar
[
Brtko J, Pascual A, Aranda A. 3,5,3’-tiiodothyronine nuclear receptors and their role in the thyroid hormone action. Endocr Exper 28, 707–115,1994.
]Search in Google Scholar
[
Brtko J, Bobalova J, Podoba J, Schmutzler C, Kohrle J. Thyroid hormone receptors and type I iodothyronine 5’-deiodinase activity of human thyroid toxic adenomas and benign cold nodules. Exp Clin Endocrinol Diabetes 110, 166–170, 2002.10.1055/s-2002-3214712058339
]Search in Google Scholar
[
Brtko J, Dvorak Z. Role of retinoids, rexinoids and thyroid hormone in the expression of cytochrome p450 enzymes. Curr Drug Metab 12, 71–88, 2011.10.2174/13892001179501688121401514
]Search in Google Scholar
[
Brtko J, Dvorak Z. Natural and synthetic retinoid X receptor ligands and their role in selected nuclear receptor action. Biochimie 179, 157–168, 2020.10.1016/j.biochi.2020.09.02733011201
]Search in Google Scholar
[
Campbell MC, Anderson GW, Mariash CN. Human spot 14 glucose and thyroid hormone response: characterization and thyroid hormone response element identification. Endocrinology 144, 5242–5248, 2003.10.1210/en.2002-000812960053
]Search in Google Scholar
[
Castillo AI, Sanchez-Martinez R, Moreno JL, Martinez-Iglesias OA, Palacios D, Aranda A. A permissive retinoid X receptor/thyroid hormone receptor heterodimer allows stimulation of prolactin gene transcription by thyroid hormone and 9-cis-retinoic acid. Mol Cell Biol 24, 502–513, 2004.10.1128/MCB.24.2.502-513.200434379214701725
]Search in Google Scholar
[
Chan S, Kilby MD. Thyroid hormone and central nervous system development. J Endocrinol 165, 1–8, 2000.10.1677/joe.0.165000110750030
]Search in Google Scholar
[
Chatterjee VK. Resistance to thyroid hormone. Horm Res 48 Suppl 4, 43–46, 1997.10.1159/0001913129350446
]Search in Google Scholar
[
Choksi NY, Jahnke GD, St Hilaire C, Shelby M. Role of thyroid hormones in human and laboratory animal reproductive health. Birth Defects Res B Dev Reprod Toxicol 68, 479–491, 2003.10.1002/bdrb.1004514745982
]Search in Google Scholar
[
Chou WY, Cheng YS, Ho CL, Liu ST, Liu PY, Kuo CC, Chang HP, Chen YH, Chang GG, Huang SM. Human spot 14 protein interacts physically and functionally with the thyroid receptor. Biochem Biophys Res Commun 357, 133–138, 2007.10.1016/j.bbrc.2007.03.10317418816
]Search in Google Scholar
[
Collado M, Serrano M. Senescence in tumours: evidence from mice and humans. Nat Rev Cancer 10, 51–57, 2010.10.1038/nrc2772367296520029423
]Search in Google Scholar
[
Contreras-Jurado C, Garcia-Serrano L, Gomez-Ferreria M, Costa C, Paramio JM, Aranda A. The thyroid hormone receptors as modulators of skin proliferation and inflammation, J Biol Chem 286, 24079–24088, 2011.10.1074/jbc.M111.218487
]Search in Google Scholar
[
Cunningham BA, Moncur JT, Huntington JT, Kinlaw WB. “Spot 14” protein: a metabolic integrator in normal and neoplastic cells. Thyroid 8, 815–825, 1998.10.1089/thy.1998.8.815
]Search in Google Scholar
[
Dahlman-Wright K, Grandien K, Nilsson S, Gustafsson JA, Carlstedt-Duke J. Protein-protein interactions between the DNA-binding domains of nuclear receptors: influence on DNA-binding. J Steroid Biochem Mol Biol 45, 239–250, 1993.10.1016/0960-0760(93)90338-W
]Search in Google Scholar
[
DeGroot LJ, Torresani J. Triiodothyronine binding to isolated liver cell nuclei. Endocrinology 96, 357–359, 1975.10.1210/endo-96-2-357
]Search in Google Scholar
[
DeGroot LJ, Coleoni AH, Rue PA, Seo H, Martino E, Refetoff S. Reduced nuclear triiodothyronine receptors in starvation-induced hypothyroidism. Biochem Biophys Res Commun 79, 173–178, 1977a.10.1016/0006-291X(77)90076-6
]Search in Google Scholar
[
DeGroot LJ, Rue P, Robertson M, Bernal J, Scherberg N. Triiodothyronine stimulates nuclear RNA synthesis. Endocrinology 101, 1690–1700, 1977b.10.1210/endo-101-6-1690
]Search in Google Scholar
[
Desouza LA, Ladiwala U, Daniel SM, Agashe S, Vaidya RA, Vaidya VA. Thyroid hormone regulates hippocampal neurogenesis in the adult rat brain. Mol Cell Neurosci 29, 414–426, 2005.10.1016/j.mcn.2005.03.010
]Search in Google Scholar
[
Dillmann WH, Schwartz HL, Oppenheimer JH. Selective alternation in hepatic enzyme response after reduction of nuclear triiodothyronine receptor sites by partial hepatectomy and starvation. Biochem Biophys Res Commun 80, 259–266, 1978.10.1016/0006-291X(78)91131-2
]Search in Google Scholar
[
Dillmann WH. Cellular action of thyroid hormone on the heart. Thyroid 12, 447–452, 2002.10.1089/10507250276014380912165105
]Search in Google Scholar
[
Dillmann WH. Cardiac hypertrophy and thyroid hormone signaling. Heart Fail Rev 15, 125–132, 2010.10.1007/s10741-008-9125-7282069519125327
]Search in Google Scholar
[
Eberhardt NL, Valcana T, Timiras PS. Triiodothyronine nuclear receptors: An in vitro comparison of the binding of triiodothyronine to nuclei of adult rat liver, cerebral hemisphere and anterior pituitary. Endocrinology 102, 556–561, 1978.10.1210/endo-102-2-55633795
]Search in Google Scholar
[
Evans RW, Farwell AP, Braverman LE. Nuclear thyroid hormone receptor in the rat uterus. Endocrinology 113, 1459–1463, 1983.10.1210/endo-113-4-14596311523
]Search in Google Scholar
[
Evans RM. The steroid and thyroid hormone receptor superfamily. Science 240, 889–895, 1988.10.1126/science.328393961598813283939
]Search in Google Scholar
[
Evans RM, Mangelsdorf DJ. Nuclear receptors, RXR & the Big Bang. Cell 157, 255–266, 2014.10.1016/j.cell.2014.03.012402951524679540
]Search in Google Scholar
[
Favre-Young H, Dif F, Roussille F, Demeneix BA, Kelly PA, Edery M, de Luze A. Cross-talk between signal transducer and activator of transcription (Stat5) and thyroid hormone receptor-beta 1 (TRbeta1) signaling pathways. Mol Endocrinol 14, 1411–1424, 2000.10.1210/mend.14.9.052510976919
]Search in Google Scholar
[
Filipcik P, Brtko J, Rauova L, Sedlakova V. Distribution of triiodothyronine nuclear receptors during the cell cycle in mouse leukemia cells. Folia Biol (Praha) 38, 332–339, 1992.
]Search in Google Scholar
[
Filipcik P, Strbak V, Brtko J. Thyroid hormone receptor occupancy and biological effects of 3,5,3,-L-triiodothyronine (T3) in GH4C1 rat pituitary tumour cells. Physiol Res 47, 41–46, 1998.
]Search in Google Scholar
[
Flamant F, Baxter JD, Forrest D, Refetoff S, Samuels H, Scanlan TS, Vennstrom B, Samarut J. International Union of Pharmacology. LIX. The pharmacology and classification of the nuclear receptor superfamily: Thyroid hormone receptors. Pharmacol Rev 58, 705–711, 2006.10.1124/pr.58.4.317132849
]Search in Google Scholar
[
Flamant F. Futures challenges in thyroid hormone signaling research. Front Endocrinol (Lausanne) 7, 58, 2016.10.3389/fendo.2016.00058491673527445973
]Search in Google Scholar
[
Flores-Morales A, Gullberg H, Fernandez L, Stahlberg N, Lee NH, Vennstrom B, Norstedt G. Patterns of liver gene expression governed by TRbeta. Mol Endocrinol 16, 1257–1268, 2002.10.1210/mend.16.6.084612040013
]Search in Google Scholar
[
Font-Diaz J, Jimenez-Panizo A, Caelles C, Vivanco MD, Perez P, Aranda A, Estebanez-Perpina E, Castrillo A, Ricote M, Valledor AF. Nuclear receptors: Lipid and hormone sensors with essential roles in the control of cancer development. Semin Cancer Biol S1044-579X(20)30267–4, 2020. Epub ahead of print.
]Search in Google Scholar
[
Frau C, Godart M, Plateroti M. Thyroid hormone regulation of intestinal epithelial stem cell biology. Mol Cell Endocrinol 459, 90–97, 2017.10.1016/j.mce.2017.03.00228288904
]Search in Google Scholar
[
Freitas FR, Capelo LP, O’Shea PJ, Jorgetti V, Moriscot AS, Scanlan TS, Williams GR, Zorn TM, Gouveia CH. The thyroid hormone receptor beta-specific agonist GC-1 selectively affects the bone development of hypothyroid rats. J Bone Miner Res 20, 294–304, 2005.10.1359/JBMR.04111615647824
]Search in Google Scholar
[
Germain P, Chambon P, Eichele G, Evans RM, Lazar MA, Leid M, De Lera AR, Lotan R, Mangelsdorf DJ, Gronemeyer H. International Union of Pharmacology. LXIII. Retinoid X receptors. Pharmacol Rev 58, 760–772, 2006a.10.1124/pr.58.4.7
]Search in Google Scholar
[
Germain P, Staels B, Dacquet C, Spedding M, Laudet V. Overview of nomenclature of nuclear receptors. Pharmacol. Rev 58, 685–704, 2006b.10.1124/pr.58.4.2
]Search in Google Scholar
[
Giammanco M, Di Liegro CM, Schiera G, Di Liegro I. Genomic and non-genomic mechanisms of action of thyroid hormones and their catabolite 3,5-diiodo-L-thyronine in mammals. Int J Mol Sci 21, 4140, 2020.10.3390/ijms21114140
]Search in Google Scholar
[
Gick GG, Ismail-Beigi F, Edelman IS. Thyroidal regulation of rat renal and hepatic Na,K-ATPase gene expression. J Biol Chem 263, 16610–16618, 1988.10.1016/S0021-9258(18)37434-9
]Search in Google Scholar
[
Gick GG, Ismail-Beigi F. Thyroid hormone induction of Na(+)-K(+)-ATPase and its mRNAs in a rat liver cell line. Am J Physiol 258, C544–C551, 1990.10.1152/ajpcell.1990.258.3.C544
]Search in Google Scholar
[
Giera S, Bansal R, Ortiz-Toro TM, Taub DG, Zoeller RT. Individual polychlorinated biphenyl (PCB) congeners produce tissue- and gene-specific effects on thyroid hormone signaling during development. Endocrinology 152, 2909–2919, 2011.10.1210/en.2010-1490
]Search in Google Scholar
[
Giguere V, Ong ES, Segui P, Evans RM. Identification of a receptor for the morphogen retinoic acid. Nature 330, 624–629, 1987.10.1038/330624a0
]Search in Google Scholar
[
Giguere V, Yang N, Segui P, Evans RM. Identification of a new class of steroid hormone receptors. Nature 331, 91–94, 1988.10.1038/331091a0
]Search in Google Scholar
[
Glass CK, Franco R, Weinberger C, Albert VR, Evans RM, Rosenfeld MG. A c-erb-A binding site in rat growth hormone gene mediates trans-activation by thyroid hormone. Nature 329(6141), 738–741, 1987.10.1038/329738a0
]Search in Google Scholar
[
Glass CK, Holloway JM, Devary OV, Rosenfeld MG. The thyroid hormone receptor binds with opposite transcriptional effects to a common sequence motif in thyroid hormone and estrogen response elements. Cell 54, 313–323, 1988.10.1016/0092-8674(88)90194-8
]Search in Google Scholar
[
Glass CK, Holloway JM. Regulation of gene expression by the thyroid hormone receptor. Biochim Biophys Acta 1032, 157–176, 1990.10.1016/0304-419X(90)90002-I
]Search in Google Scholar
[
Glass CK. Some new twists in the regulation of gene expression by thyroid hormone and retinoic acid receptors. J Endocrinol 150, 349–357, 1996.10.1677/joe.0.1500349
]Search in Google Scholar
[
Green S, Chambon P. Nuclear receptors enhance our understanding of transcription regulation. Trends Genet 4, 309–314, 1988.10.1016/0168-9525(88)90108-4
]Search in Google Scholar
[
Gogakos AI, Duncan Bassett JH, Williams GR. Thyroid and bone. Arch Biochem Biophys 503, 129–136, 2010.10.1016/j.abb.2010.06.021
]Search in Google Scholar
[
Gonzalez-Sancho JM, Garcia V, Bonilla F, Munoz A. Thyroid hormone receptors/THR genes in human cancer. Cancer Lett 192, 121–132, 2003.10.1016/S0304-3835(02)00614-6
]Search in Google Scholar
[
Gross J, Pitt-Rivers R. The identification of 3,5,3’-L-triiodothyronine in human plasma. Lancet 259, 439–441, 1952.10.1016/S0140-6736(52)91952-1
]Search in Google Scholar
[
Guigon CJ, Kim DW, Willingham MC, Cheng SY. Mutation of thyroid hormone receptor-Β in mice predisposes to the development of mammary tumors. Oncogene 30, 3384–3390, 2011.10.1038/onc.2011.50345778121399657
]Search in Google Scholar
[
Gustafson TA, Markham BE, Bahl JJ, Morkin E. Thyroid hormone regulates expression of a transfected alpha-myosin heavy-chain fusion gene in fetal heart cells. Proc Natl Acad Sci USA 84, 3122–3126, 1987.10.1073/pnas.84.10.31223048203472199
]Search in Google Scholar
[
Harington CR, Barger G. Chemistry of thyroxine: Constitution and synthesis of thyroxine. Biochem J 21, 169–183, 1927.10.1042/bj0210169125188616743801
]Search in Google Scholar
[
Harvey CB, Williams GR. Mechanism of thyroid hormone action. Thyroid 12, 441–446, 2002.10.1089/10507250276014379112165104
]Search in Google Scholar
[
Hashimoto K, Cohen RN, Yamada M, Markan KR, Monden T, Satoh T, Mori M, Wondisford FE. Cross-talk between thyroid hormone receptor and liver X receptor regulatory pathways is revealed in a thyroid hormone resistance mouse model. J Biol Chem 281, 295–302, 2006.10.1074/jbc.M507877200
]Search in Google Scholar
[
Hashimoto K, Mori M. Crosstalk of thyroid hormone receptor and liver X receptor in lipid metabolism and beyond. Endocr J 58, 921–930, 2011.10.1507/endocrj.EJ11-0114
]Search in Google Scholar
[
Hernandez A. Thyroid hormone role and economy in the developing testis. Vitam Horm 106, 473–500, 2018.10.1016/bs.vh.2017.06.005
]Search in Google Scholar
[
Hernandez A, Martinez ME. Thyroid hormone action in the developing testis: intergenerational epigenetics. J Endocrinol 244, R33–R46, 2020.10.1530/JOE-19-0550
]Search in Google Scholar
[
Heyman RA, Mangelsdorf DJ, Dyck JA, Stein RB, Eichele G, Evans RM, Thaller C. 9-cis retinoic acid is a high affinity ligand for the retinoid X receptor. Cell 68, 397–406, 1992.10.1016/0092-8674(92)90479-V
]Search in Google Scholar
[
Horlein AJ, Naar AM, Heinzel T, Torchia J, Gloss B, Kurokawa R, Ryan A, Kamei Y, Soderstrom M, Glass CK, Rosen-feld MG. Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor. Nature 377, 397–404. 1995.10.1038/377397a0
]Search in Google Scholar
[
Hubbard JR, Kalimi M. Influence of proteinase inhibitors on glucocorticoid receptor properties: recent progress and future perspectives. Mol Cell Biochem 66, 101–109, 1985.10.1007/BF00220777
]Search in Google Scholar
[
Ichikawa K, Brtko J, DeGroot LJ, Hashizume K, Yamada T. Stabilization, accurate determination, and purification of rat liver nuclear thyroid hormone receptor. J Endocrinol 120, 237–243, 1989.10.1677/joe.0.1200237
]Search in Google Scholar
[
Iglesias P, Bajo MA, Selgas R, Diez JJ. Thyroid dysfunction and kidney disease: An update. Rev Endocr Metab Disord 18, 131–144, 2017.10.1007/s11154-016-9395-7
]Search in Google Scholar
[
Ito M, Roeder RG. The TRAP/SMCC/mediator complex and thyroid hormone receptor function. Trends Endocrinol Metab 12, 127–134, 2001.10.1016/S1043-2760(00)00355-6
]Search in Google Scholar
[
Jazdzewski K, Boguslawska J, Jendrzejewski J, Liyanarachchi S, Pachucki J, Wardyn KA, Nauman A, de la Chapelle A. Thyroid hormone receptor beta (THRB) is a major target gene for microRNAs deregulated in papillary thyroid carcinoma (PTC). J Clin Endocrinol Metab 96, E546–E553, 2011.10.1210/jc.2010-1594
]Search in Google Scholar
[
James SR, Franklyn JA, Kilby MD. Placental transport of thyroid hormone. Best Pract Res Clin Endocrinol Metab 21, 253–264, 2007.10.1016/j.beem.2007.03.001
]Search in Google Scholar
[
Jerzak KJ, Cockburn J, Pond GR, Pritchard KI, Narod SA, Dhesy-Thind SK, Bane A. Thyroid hormone receptor α in breast cancer: prognostic and therapeutic implications. Breast Cancer Res Treat 149, 293–301, 2015.10.1007/s10549-014-3235-9
]Search in Google Scholar
[
Jerzak KJ, Cockburn JG, Dhesy-Thind SK, Pond GR, Pritchard KI, Nofech Mozes S, Sun P, Narod SA, Bane A. Thyroid hormone receptor beta-1 expression in early breast cancer: a validation study. Breast Cancer Res Treat 171, 709–717, 2018.10.1007/s10549-018-4844-5
]Search in Google Scholar
[
Joseph B, Ji M, Liu D, Hou P, Xing M. Lack of mutations in the thyroid hormone receptor (TR) alpha and beta genes but frequent hypermethylation of the TRbeta gene in differentiated thyroid tumors. J Clin Endocrinol Metab 92, 4766–4770, 2007.10.1210/jc.2007-0812
]Search in Google Scholar
[
Jump DB, Narayan P, Towle H, Oppenheimer JH. Rapid effects of triiodothyronine on hepatic gene expression. Hybridization analysis of tissue-specific triiodothyronine regulation of mRNAS14. J Biol Chem 259, 2789–2797, 1984.10.1016/S0021-9258(17)43215-7
]Search in Google Scholar
[
Kahaly GJ, Dillmann WH. Thyroid hormone action in the heart. Endocr Rev 26, 704–728, 2005.10.1210/er.2003-003315632316
]Search in Google Scholar
[
Kendall EC. The isolation in crystalline form of the compound containing iodine, which occurs in the thyroid: Its chemical nature and physiologic activity. J Am Med Assoc 64, 2042–2043, 1915.10.1001/jama.1915.02570510018005
]Search in Google Scholar
[
Kim WG, Cheng SY. Thyroid hormone receptors and cancer. Biochim Biophys Acta 1830, 3928–3936, 2013.10.1016/j.bbagen.2012.04.002340624422507269
]Search in Google Scholar
[
Kliewer SA, Umesono K, Mangelsdorf DJ, Evans RM. Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling. Nature 355, 446–449, 1992.10.1038/355446a061598851310351
]Search in Google Scholar
[
Koenig RJ, Warne RL, Brent GA, Harney JW, Larsen PR, Moore DD. Isolation of a cDNA clone encoding a biologically active thyroid hormone receptor. Proc Natl Acad Sci USA 85, 5031–5035, 1988.10.1073/pnas.85.14.5031
]Search in Google Scholar
[
Koenig RJ. Regulation of type 1 iodothyronine deiodinase in health and disease. Thyroid 15, 835–840, 2005.10.1089/thy.2005.15.835
]Search in Google Scholar
[
Koerner D, Schwartz HL, Surks MI, Oppenheimer JH, Jorgensen EC. Binding of selected iodothyronine analogues to receptor sites of isolated rat hepatic nuclei: High correlation between structural requirements for nuclear binding and biological activity. J Biol Chem 250, 6417–6423, 1975.10.1016/S0021-9258(19)41080-6
]Search in Google Scholar
[
Kohrle J. Guard your master: thyroid hormone receptors protect their gland of origin from thyroid cancer. Endocrinology 145, 4427–4429, 2004.10.1210/en.2004-092815375080
]Search in Google Scholar
[
Krezel W, Ruhl R, de Lera AR. Alternative retinoid X receptor (RXR) ligands. Mol Cell Endocrinol 491, 110436, 2019.10.1016/j.mce.2019.04.01631026478
]Search in Google Scholar
[
La Vignera S, Vita R. Thyroid dysfunction and semen quality. Int J Immunopathol Pharmacol 32, 2058738418775241, 2018.10.1177/2058738418775241594658729737216
]Search in Google Scholar
[
Lademann F, Tsourdi E, Hofbauer LC, Rauner M. Thyroid hormone actions and bone remodeling - The role of the Wnt signaling pathway. Exp Clin Endocrinol Diabetes 128, 450–454, 2020.10.1055/a-1088-121531958849
]Search in Google Scholar
[
Ladenson PW, Bloch KD, Seidman JG. Modulation of atrial natriuretic factor by thyroid hormone: Messenger ribonucleic acid and peptide levels in hypothyroid, euthyroid, and hyperthyroid rat atria and ventricles. Endocrinology 123, 652–657, 1988.10.1210/endo-123-1-6522968239
]Search in Google Scholar
[
Laudet V, Hanni C, Coll J, Catzeflis F, Stehelin D. Evolution of the nuclear receptor gene superfamily. EMBO J 11, 1003–1013, 1992.10.1002/j.1460-2075.1992.tb05139.x5565411312460
]Search in Google Scholar
[
Laudet V. Evolution of the nuclear receptor superfamily: Early diversification from an ancestral orphan receptor. J Mol Endocrinol 19, 207–226, 1997.10.1677/jme.0.01902079460643
]Search in Google Scholar
[
Leitman DC, Costa CH, Graf H, Baxter JD, Ribeiro RC. Thyroid hormone activation of transcription is potentiated by activators of cAMP-dependent protein kinase. J Biol Chem 271, 21950–21955, 1996.10.1074/jbc.271.36.21950
]Search in Google Scholar
[
Li D, Li T, Wang F, Tian H, Samuels HH. Functional evidence for retinoid X receptor (RXR) as a nonsilent partner in the thyroid hormone receptor/RXR heterodimer. Mol Cell Biol 22, 5782–5792, 2002.10.1128/MCB.22.16.5782-5792.2002
]Search in Google Scholar
[
Li H, Leo C, Schroen DJ, Chen JD. Characterization of receptor interaction and transcriptional repression by the corepressor SMRT. Mol Endocrinol 11, 2025–2037, 1997.10.1210/mend.11.13.0028
]Search in Google Scholar
[
Liaw CW, Towle HC. Characterization of a thyroid hormone-responsive gene from rat. J Biol Chem 259, 7253–7260, 1984.10.1016/S0021-9258(17)39865-4
]Search in Google Scholar
[
Liu YC, Yeh CT, Lin KH. Molecular functions of thyroid hormone signaling in regulation of cancer progression and anti-apoptosis. Int J Mol Sci 20, 4986, 2019.10.3390/ijms20204986683415531600974
]Search in Google Scholar
[
Liu YY, Brent GA. Thyroid hormone crosstalk with nuclear receptor signaling in metabolic regulation. Trends Endocrinol Metab 21, 166–173, 2010.10.1016/j.tem.2009.11.004283116120015660
]Search in Google Scholar
[
Lu C, Cheng SY. Thyroid hormone receptors regulate adipogenesis and carcinogenesis via crosstalk signaling with peroxisome proliferator-activated receptors. J Mol Endocrinol 44, 143–154, 2010.10.1677/JME-09-0107346409519741045
]Search in Google Scholar
[
Maia AL, Kieffer JD, Harney JW, Larsen PR. Effect of 3,5,3’-Triiodothyronine (T3) administration on dio1 gene expression and T3 metabolism in normal and type 1 deiodinase-deficient mice. Endocrinology 136, 4842–4849, 1995.10.1210/endo.136.11.75882157588215
]Search in Google Scholar
[
Macejova D, Baranova M, Liska J, Brtko J. Expression of nuclear hormone receptors, their coregulators and type I iodothyronine 5’-deiodinase gene in mammary tissue of nonlactating and postlactating rats. Life Sci 77, 2584–2593, 2005.10.1016/j.lfs.2005.02.02415946693
]Search in Google Scholar
[
Macejova D, Podoba J, Toporova L, Grigerova M, Kajo K, Machalekova K, Brtko J. Causal associations of autoimmune thyroiditis and papillary thyroid carcinoma: mRNA expression of selected nuclear receptors and other molecular targets. Oncol Lett 18, 4270–4277, 2019.10.3892/ol.2019.10770675725531579073
]Search in Google Scholar
[
Mancino G, Miro C, Di Cicco E, Dentice M. Thyroid hormone action in epidermal development and homeostasis and its implications in the pathophysiology of the skin. J Endocrinol Invest 2021. Epub ahead of print.10.1007/s40618-020-01492-2828534833683663
]Search in Google Scholar
[
Mangelsdorf DJ, Ong ES, Dyck JA, Evans RM. Nuclear receptor that identifies a novel retinoic acid response pathway. Nature 345, 224–229, 1990.10.1038/345224a02159111
]Search in Google Scholar
[
Mangelsdorf DJ, Borgmeyer U, Heyman RA, Zhou JY, Ong ES, Oro AE, Kakizuka A, Evans RM. Characterization of three RXR genes that mediate the action of 9-cis retinoic acid. Genes Dev 6, 329–344, 1992.10.1101/gad.6.3.3291312497
]Search in Google Scholar
[
Marimuthu A, Feng W, Tagami T, Nguyen H, Jameson JL, Fletterick RJ, Baxter JD, West BL. TR surfaces and conformations required to bind nuclear receptor corepressor. Mol Endocrinol 16, 271–286. 2002.10.1210/mend.16.2.077711818500
]Search in Google Scholar
[
Marketos S, Eftychiadis A, Koutras DA. Thyroid diseases in the Byzantine era. J R Soc Med 83, 111–113, 1990.10.1177/01410768900830021812925102181133
]Search in Google Scholar
[
Martinez-deMena R, Hernandez A, Obregon MJ. Triiodothyronine is required for the stimulation of type II 5’-deiodinase mRNA in rat brown adipocytes. Am J Physiol Endocrinol Metab 282, E1119–E1127, 2002.10.1152/ajpendo.00433.200111934678
]Search in Google Scholar
[
Maruo T, Katayama K, Barnea ER, Mochizuki M. A role for thyroid hormone in the induction of ovulation and corpus luteum function. Horm Res 37, 12–18,1992.10.1159/0001823381427622
]Search in Google Scholar
[
Mathisen PM, Miller L. Thyroid hormone induces constitutive keratin gene expression during Xenopus laevis development. Mol Cell Biol 9, 1823–1831, 1989.10.1128/mcb.9.5.1823-1831.19893629722473388
]Search in Google Scholar
[
Mengeling BJ, Furlow JD. Pituitary specific retinoid-X receptor ligand interactions with thyroid hormone receptor signaling revealed by high throughput reporter and endogenous gene responses. Toxicol In Vitro 29, 1609–1618, 2015.10.1016/j.tiv.2015.06.01826096596
]Search in Google Scholar
[
Metivier R, Reid G, Gannon F. Transcription in four dimensions: nuclear receptor-directed initiation of gene expression. EMBO reports 7, 161–167, 2006.10.1038/sj.embor.7400626136925416452926
]Search in Google Scholar
[
Metz LD, Seidler FJ, McCook EC, Slotkin TA. Cardiac alpha-adrenergic receptor expression is regulated by thyroid hormone during a critical developmental period. J Mol Cell Cardiol 28, 1033–1044, 1996.10.1006/jmcc.1996.00968762041
]Search in Google Scholar
[
Mintz G, Pizzarello R, Klein I. Enhanced left ventricular diastolic function in hyperthyroidism: noninvasive assessment and response to treatment. J Clin Endocrinol Metab 73, 146–150, 1991.10.1210/jcem-73-1-1462045465
]Search in Google Scholar
[
Montero-Pedrazuela A, Venero C, Lavado-Autric R, Fernandez-Lamo I, Garcia-Verdugo JM, Bernal J, Guadano-Ferraz A. Modulation of adult hippocampal neurogenesis by thyroid hormones: implications in depressive-like behavior. Mol Psychiatry 11, 361–371, 2006.10.1038/sj.mp.400180216446739
]Search in Google Scholar
[
Morkin E, Edwards JG, Tsika RW, Bahl JJ, Flink IL. Regulation of human cardiac myosin heavy chain gene expression by thyroid hormone. Adv Exp Med Biol 308, 143–147, 1991.10.1007/978-1-4684-6015-5_121801581
]Search in Google Scholar
[
Morkin E. Regulation of myosin heavy chain genes in the heart. Circulation 87, 1451–1460, 1993.10.1161/01.CIR.87.5.1451
]Search in Google Scholar
[
Morte B, Manzano J, Scanlan T, Vennstrom B, Bernal J. Deletion of the thyroid hormone receptor alpha 1 prevents the structural alterations of the cerebellum induced by hypothyroidism. Proc Natl Acad Sci USA 99, 3985–3989, 2002.10.1073/pnas.06241329912263511891331
]Search in Google Scholar
[
Naidoo S, Valcana T, Timiras PS. Thyroid hormone receptors in the developing rat brain. Amer Zool 18, 545–552, 1978.10.1093/icb/18.3.545
]Search in Google Scholar
[
Nelson CC, Hendy SC, Faris JS, Romaniuk PJ. The effects of P-box substitutions in thyroid hormone receptor on DNA binding specificity. Mol Endocrinol 8, 829–840, 1994.10.1210/mend.8.7.79841457984145
]Search in Google Scholar
[
Nevado J, Tenbaum SP, Aranda A. hSrb7, an essential human mediator component, acts as a coactivator for the thyroid hormone receptor. Mol. Cell. Endocrinol 222, 41–51, 2004.10.1016/j.mce.2004.05.00315249124
]Search in Google Scholar
[
Niazi AK, Kalra S, Irfan A, Aliya Islam A. Thyroidology over the ages. Indian J Endocrinol Metab 15 (Suppl 2), S121–S126, 2011.10.4103/2230-8210.83347316985921966648
]Search in Google Scholar
[
Norman MF, Lavin TN, Baxter JD, West BL. The rat growth hormone gene contains multiple thyroid response elements. J Biol Chem 264, 12063–12073, 1989.10.1016/S0021-9258(18)80174-0
]Search in Google Scholar
[
Oppenheimer JH, Koerner D, Schwartz HL, Surks MI. Specific nuclear triiodothyronine binding sites in rat liver and kidney. J Clin Endocrinol Metab 35, 330–333, 1972.10.1210/jcem-35-2-330
]Search in Google Scholar
[
Oppenheimer JH, Schwartz HL, Surks MI. Tissue differences in the concentration of triiodothyronine nuclear binding sites in the rat: Liver, kidney, pituitary, heart, brain, spleen and testes. Endocrinology 95, 897–903, 1974.10.1210/endo-95-3-897
]Search in Google Scholar
[
Oppenheimer JH, Schwartz HL, Surks MI, Koerner D, Dillmann WH. Nuclear receptors and the initiation of thyroid hormone action. Recent Prog Horm Res 32, 529–565, 1976.10.1016/B978-0-12-571132-6.50029-4
]Search in Google Scholar
[
Oppenheimer JH. Evolving concepts of thyroid hormone action. Biochimie 81, 539–543, 1999.10.1016/S0300-9084(99)80107-2
]Search in Google Scholar
[
Ortega FJ, Vazquez-Martin A, Moreno-Navarrete JM, Bassols J, Rodriguez-Hermosa J, Girones J, Ricart W, Peral B, Tinahones FJ, Fruhbeck G, Menendez JA, Fernandez-Real JM. Thyroid hormone responsive Spot 14 increases during differentiation of human adipocytes and its expression is down-regulated in obese subjects. Int J Obes (Lond) 34, 487–499, 2010.10.1038/ijo.2009.263
]Search in Google Scholar
[
Pascual A, Aranda A. Thyroid hormone receptors, cell growth and differentiation. Biochim Biophys Acta 1830, 3908–3916, 2013.10.1016/j.bbagen.2012.03.012
]Search in Google Scholar
[
Petty KJ, Morioka H, Mitsuhashi T, Nikodem VM. Thyroid hormone regulation of transcription factors involved in malic enzyme gene expression. J Biol Chem 264, 11483–11490, 1989.10.1016/S0021-9258(18)60489-2
]Search in Google Scholar
[
Plateroti M, Chassande O, Fraichard A, Gauthier K, Freund JN, Samarut J, Kedinger M. Involvement of T3Ralphaand beta-receptor subtypes in mediation of T3 functions during postnatal murine intestinal development. Gastroenterology 116, 1367–1378, 1999.10.1016/S0016-5085(99)70501-9
]Search in Google Scholar
[
Plateroti M, Gauthier K, Domon-Dell C, Freund JN, Samarut J, Chassande O. Functional interference between thyroid hormone receptor alpha (TRalpha) and natural truncated TRDeltaalpha isoforms in the control of intestine development. Mol Cell Biol 21, 4761–4772, 2001.10.1128/MCB.21.14.4761-4772.20018716011416151
]Search in Google Scholar
[
Poddar R, Paul S, Chaudhury S, Sarkar PK. Regulation of actin and tubulin gene expression by thyroid hormone during rat brain development. Brain Res Mol Brain Res 35, 111–118, 1996.10.1016/0169-328X(95)00189-Y
]Search in Google Scholar
[
Puca GA, Abbondanza C, Nigro V, Armetta I, Medici N, Molinari AM. Estradiol receptor has proteolytic activity that is responsible for its own transformation. Proc Natl Acad Sci USA 83, 5367–5371, 1986.10.1073/pnas.83.15.53673862872426695
]Search in Google Scholar
[
Puzianowska-Kuznicka M, Krystyniak A, Madej A, Cheng SY, Nauman J. Functionally impaired TR mutants are present in thyroid papillary cancer. J Clin Endocrinol Metab 87, 1120–1128, 2002.10.1210/jcem.87.3.829611889175
]Search in Google Scholar
[
Refetoff S, DeWind LT, DeGroot LJ. Familial syndrome combining deaf-mutism, stuppled epiphyses, goiter and abnormally high PBI: possible target organ refractoriness to thyroid hormone. J Clin Endocrinol Metab 27, 279–294, 1967.10.1210/jcem-27-2-2794163616
]Search in Google Scholar
[
Refetoff S, Dumitrescu AM. Syndromes of reduced sensitivity to thyroid hormone: genetic defects in hormone receptors, cell transporters and deiodination. Best Pract Res Clin Endocrinol Metab 21, 277–305, 2007.10.1016/j.beem.2007.03.00517574009
]Search in Google Scholar
[
Refetoff S, Bassett JH, Beck-Peccoz P, Bernal J, Brent G, Chatterjee K, De Groot LJ, Dumitrescu AM, Jameson JL, Kopp PA, Murata Y, Persani L, Samarut J, Weiss RE, Williams GR, Yen PM. Classification and proposed nomenclature for inherited defects of thyroid hormone action, cell transport, and metabolism. J Clin Endocrinol Metab 99, 768–770, 2014.10.1210/jc.2013-3393394223624823702
]Search in Google Scholar
[
Ritter MJ, Amano I, Hollenberg AN. Thyroid hormone signaling and the liver. Hepatology 72, 742–752, 2020.10.1002/hep.3129632343421
]Search in Google Scholar
[
Rosenfeld MG, Lunyak VV, Glass CK. Sensors and signals: A coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response. Genes Dev 20, 1405–1428, 2006.10.1101/gad.142480616751179
]Search in Google Scholar
[
Ruiz-Llorente L, Ardila-Gonzalez S, Fanjul LF, Martinez-Iglesias O, Aranda A. microRNAs 424 and 503 are mediators of the anti-proliferative and anti-invasive action of the thyroid hormone receptor beta. Oncotarget 5, 2918–2933, 2014.10.18632/oncotarget.1577410278024796297
]Search in Google Scholar
[
Samuels HH, Tsai JS. Thyroid hormone action in cell culture: demonstration of nuclear receptors in intact cells and isolated nuclei. Proc Natl Acad Sci USA 70, 3488–3492, 1973.10.1073/pnas.70.12.34884272654357872
]Search in Google Scholar
[
Samuels HH, Tsai JS, Casanova J. Thyroid hormone action: In vitro demonstration of putative receptors in isolated nuclei and soluble nuclear extracts. Science 184, 1188–1191, 1974.10.1126/science.184.4142.1188
]Search in Google Scholar
[
Samuels HH, Stanley F, Casanova J. Relationship of receptor affinity to the modulation of thyroid hormone nuclear receptor levels and growth hormone synthesis by L-triiodothyronine and iodothyronine analogues in cultured GH1 cells. J Clin Invest 63, 1229–1240, 1979.10.1172/JCI109418
]Search in Google Scholar
[
Sanchez-Martinez R, Castillo AI, Steinmeyer A, Aranda A. The retinoid X receptor ligand restores defective signalling by the vitamin D receptor, EMBO Rep 7, 1030–1034, 2006.10.1038/sj.embor.7400776
]Search in Google Scholar
[
Sap J, Munoz A, Damm K, Goldberg Y, Ghysdael J, Leutz A, Beug H, Vennstrom B. The c-erb-A protein is a high-affinity receptor for thyroid hormone. Nature 324, 635–640, 1986.10.1038/324635a0
]Search in Google Scholar
[
Schmutzler C, Brtko J, Winzer R, Jakobs TC, Meissner-Weigl J, Simon D, Goretzki PE, Kohrle J. Functional retinoid and thyroid hormone receptors in human thyroid-carcinoma cell lines and tissues. Int J Cancer 76, 368–376, 1998.10.1002/(SICI)1097-0215(19980504)76:3<368::AID-IJC14>3.0.CO;2-7
]Search in Google Scholar
[
Shibata H, Spencer TE, Onate SA, Jenster G, Tsai SY, Tsai MJ, O’Malley BW. Role of co-activators and co-repressors in the mechanism of steroid/thyroid receptor action. Recent Prog Horm Res 52, 141–164, 1997.
]Search in Google Scholar
[
Silva JF, Ocarino NM, Serakides R. Thyroid hormones and female reproduction. Biol Reprod 99, 907–921, 2018.10.1093/biolre/ioy115
]Search in Google Scholar
[
Simonet WS, Ness GC. Transcriptional and posttranscriptional regulation of rat hepatic 3-hydroxy-3-methylglutaryl-coenzyme A reductase by thyroid hormones. J Biol Chem 263, 12448–12453,1988.10.1016/S0021-9258(18)37775-5
]Search in Google Scholar
[
Smith CL, O’Malley BW. Coregulator function: A key to understanding tissue specificity of selective receptor modulators. Endocr Rev 25, 45–71, 2004.10.1210/er.2003-0023
]Search in Google Scholar
[
Spaulding SW, Davis PJ. Thyroxine binding to soluble proteins in rat liver and its sex dependence. Biochim Biophys Acta 229, 279–283, 1971.10.1016/0005-2795(71)90345-X
]Search in Google Scholar
[
Sterling K, Milch PO, Brenner MA, Lazarus JH. Thyroid hormone action: the mitochondrial pathway. Science 197, 996–999, 1977.10.1126/science.196334
]Search in Google Scholar
[
Sugie H, Verity MA. Postnatal histochemical fiber type differentiation in normal and hypothyroid rat soleus muscle. Muscle Nerve 8, 654–660,1985.10.1002/mus.880080805
]Search in Google Scholar
[
Sun H, Cao L, Zheng R, Xie S, Liu C. Update on resistance to thyroid hormone syndrome β. Ital J Pediatr 46, 168, 2020.10.1186/s13052-020-00929-x
]Search in Google Scholar
[
Surks MI, Koerner D, Dillmann W, Oppenheimer JH. Limited capacity binding sites for L-triiodothyronine (T3) in rat liver nuclei: Localization to the chromatin and partial characterization of the T3-chromatin complex, J Biol Chem 248, 7066–7072, 1973.10.1016/S0021-9258(19)43362-0
]Search in Google Scholar
[
Surks MI, Koerner DH, Oppenheimer JH. In vitro binding of L-triiodothyronine to receptors in rat liver nuclei: Kinetics of binding, extraction properties, and lack of requirement for cytosol proteins J Clin Invest 55, 50–60, 1975.10.1172/JCI107917
]Search in Google Scholar
[
Tabachnick II, Bonnycastle DD, Salter WT. The distribution of 131I- and 131I-labelled thyroxine in rat liver homogenates. J Endocrinol 10, 302–304, 1954.10.1677/joe.0.0100302
]Search in Google Scholar
[
Tang Y, Yu M, Lian X. Resistance to thyroid hormone α, revelation of basic study to clinical consequences. J Pediatr Endocrinol Metab 29, 511–522, 2016.10.1515/jpem-2015-0286
]Search in Google Scholar
[
Tata JR, Ernster L, Suranyi EM. Interaction between thyroid hormones and cellular constituents. I. Binding to isolated sub-cellular particles and sub-particulate fractions. Biochim Biophys Acta 60, 461–479, 1962.10.1016/0006-3002(62)90866-1
]Search in Google Scholar
[
Tata JR, Ernster L, Lindberg O, Arrhenius E, Pederson S, Hedman R. The action of thyroid hormones at the cell level. Biochem J 86, 408–428, 1967.10.1042/bj0860408120177513993432
]Search in Google Scholar
[
Thompson CC, Weinberger C, Lebo R, Evans RM. Identification of a novel thyroid hormone receptor expressed in the mammalian central nervous system. Science 237, 1610–1614, 1987.10.1126/science.36292593629259
]Search in Google Scholar
[
Torresani J, DeGroot LJ. Triiodothyronine binding to liver nuclear solubilized proteins in vitro. Endocrinology 96, 1201–1209, 1975.10.1210/endo-96-5-1201235420
]Search in Google Scholar
[
Tribulova N, Kurahara LH, Hlivak P, Hirano K, Szeiffova Bacova B. Pro-arrhythmic signaling of thyroid hormones and its relevance in subclinical hyperthyroidism. Int J Mol Sci 21, 2844, 2020.10.3390/ijms21082844
]Search in Google Scholar
[
Umesono K, Evans RM. Determinants of target gene specificity for steroid/thyroid hormone receptors. Cell 57, 1139–1146, 1989.10.1016/0092-8674(89)90051-2
]Search in Google Scholar
[
Usala SJ, Bale AE, Gesundheit N, Weinberger C, Lash RW, Wondisford FE, McBride OW, Weintraub BD. Tight linkage between the syndrome of generalized thyroid hormone resistance and the human c-erbA beta gene. Mol Endocrinol 12, 1217–1220, 1988a.10.1210/mend-2-12-12172905763
]Search in Google Scholar
[
Usala SJ, Young WS 3rd, Morioka H, Nikodem VM. The effect of thyroid hormone on the chromatin structure and expression of the malic enzyme gene in hepatocytes. Mol Endocrinol 2, 619–626, 1988b.10.1210/mend-2-7-6193412327
]Search in Google Scholar
[
Vallejo CG, Seguido AM, Testillano PS, Risueno MC. Thyroid hormone regulates tubulin expression in mammalian liver. Effects of deleting thyroid hormone receptor-alpha or -beta. Am J Physiol Endocrinol Metab 289, E87– E94, 2005.10.1152/ajpendo.00436.200415713690
]Search in Google Scholar
[
Verga Falzacappa C, Panacchia L, Bucci B, Stigliano A, Cavallo MG, Brunetti E, Toscano V, Misiti S. 3,5,3′-Triiodothyronine (T3) is a survival factor for pancreatic beta-cells undergoing apoptosis. J Cell Physiol 206, 309–321, 2006.10.1002/jcp.2046016021636
]Search in Google Scholar
[
Viguerie N, Langin D. Effect of thyroid hormone on gene expression. Curr Opin Clin Nutr Metab Care 6, 377–381, 2003.10.1097/00075197-200307000-00004
]Search in Google Scholar
[
Visser WE. Therapeutic applications of thyroid hormone analogues. Ann Endocrinol (Paris) 4, S0003–4266(20)30039–1, 2020. Epub ahead of print.
]Search in Google Scholar
[
Wahlstrom GM, Sjoberg M, Andersson M, Nordstrom K, Vennstrom B. Binding characteristics of the thyroid hormone receptor homo- and heterodimers to consensus AGGTCA repeat motifs. Mol Endocrinol 6, 1013–1022, 1992.10.1210/me.6.7.1013
]Search in Google Scholar
[
Waung JA, Bassett JH, Williams GR. Thyroid hormone metabolism in skeletal development and adult bone maintenance. Trends Endocrinol Metab 23, 155–162, 2012.10.1016/j.tem.2011.11.00222169753
]Search in Google Scholar
[
Weinberger C, Thompson CC, Ong ES, Lebo R, Gruol DJ, Evans RM. The c-erb-A gene encodes a thyroid hormone receptor. Nature 324, 641–646, 1986.10.1038/324641a02879243
]Search in Google Scholar
[
Weiss RE, Xu J, Ning G, Pohlenz J, O’Malley BW, Refetoff S. Mice deficient in the steroid receptor co-activator 1 (SRC-1) are resistant to thyroid hormone. Embo J 18, 1900–1904. 1999.10.1093/emboj/18.7.1900
]Search in Google Scholar
[
Williams GR. Cloning and characterization of two novel thyroid hormone receptor beta isoforms. Mol Cell Biol 20, 8329–8342, 2000.10.1128/MCB.20.22.8329-8342.2000
]Search in Google Scholar
[
Yamada S, Kakuta H. Retinoid X receptor ligands: A patent review (2007 - 2013). Expert Opin Ther Pat 24, 443–452, 2014.10.1517/13543776.2014.880692
]Search in Google Scholar
[
Ye ZS, Forman BM, Aranda A, Pascual A, Park HY, Casanova J, Samuels HH. Rat growth hormone gene expression. Both cell-specific and thyroid hormone response elements are required for thyroid hormone regulation. J Biol Chem 263, 7821–7829, 1988.10.1016/S0021-9258(18)68572-2
]Search in Google Scholar
[
Yen PM. Physiological and molecular basis of thyroid hormone action. Physiol Rev 81, 1097–1142, 2001.10.1152/physrev.2001.81.3.1097
]Search in Google Scholar
[
Yen PM. Molecular basis of resistance to thyroid hormone. Trends Endocrinol Metab 14, 327–333. 2003.10.1016/S1043-2760(03)00114-0
]Search in Google Scholar
[
Yen PM, Feng X, Flamant F, Chen Y, Walker RL, Weiss RE, Chassande O, Samarut J, Refetoff S, and Meltzer PS. Effects of ligand and thyroid hormone receptor isoforms on hepatic gene expression profiles of thyroid hormone receptor knockout mice. EMBO Rep 4, 581–587, 2003.10.1038/sj.embor.embor862131920212776178
]Search in Google Scholar
[
Yin L, Wang Y, Dridi S, Vinson C, Hillgartner FB. Role of CCAAT/enhancer-binding protein, histone acetylation, and coactivator recruitment in the regulation of malic enzyme transcription by thyroid hormone. Mol Cell Endocrinol 245, 43–52, 2005.10.1016/j.mce.2005.10.00216293364
]Search in Google Scholar
[
Xiao L, Xie X, Zhai Y Functional crosstalk of CAR-LXR and ROR-LXR in drug metabolism and lipid metabolism. Adv Drug Deliv Rev 62, 1316–1321, 2010.10.1016/j.addr.2010.07.00620659512
]Search in Google Scholar
[
Zambrano A, Garcia-Carpizo V, Gallardo ME, Villamuera R, Gomez-Ferreria MA, Pascual A, Buisine N, Sachs LM, Garesse R, Aranda A. The thyroid hormone receptor β induces DNA damage and premature senescence. J Cell Biol 204, 129–146, 2014.10.1083/jcb.201305084388279524395638
]Search in Google Scholar
[
Zechel C, Shen XQ, Chen JY, Chen ZP, Chambon P, Gronemeyer H. The dimerization interfaces formed between the DNA binding domains of RXR, RAR and TR determine the binding specificity and polarity of the full-length receptors to direct repeats. EMBO J 13, 1425–1433, 1994.10.1002/j.1460-2075.1994.tb06396.x3949608137826
]Search in Google Scholar
[
Zhu XG, Zhao L, Willingham MC, Cheng SY. Thyroid hormone receptors are tumor suppressors in a mouse model of metastatic follicular thyroid carcinoma. Oncogene 29, 1909–1919, 2010.10.1038/onc.2009.476344388420062085
]Search in Google Scholar