[
1. Park SE, Sapkota K, Choi JH. et al. Rutin from Dendropanax morbifera Leveille protects human dopaminergic cells against rotenone-induced cell injury through inhibiting JNK and p38 MAPK signaling. Neurochem Res. 2014;39(4):707–18.10.1007/s11064-014-1259-5
]Search in Google Scholar
[
2. Hisahara S, Shimohama S. Toxin-induced and genetic animal models of Parkinson’s disease. Parkinsons Dis. 2011;2011:9517–9.10.4061/2011/951709
]Search in Google Scholar
[
3. Enogieru AB, Haylett W, Hiss DC, Bardien S, Ekpo OE. Rutin as a potent antioxidant: implications for neurodegenerative disorders. Oxi Med Cell Longev. 2018;ID 6241017:1–17.10.1155/2018/6241017
]Search in Google Scholar
[
4. Doughari JH. Phytochemicals: Extraction methods, basic structures and mode of action as potential chemotherapeutic agents, phytochemicals – A global perspective of their role in nutrition and health. [http://www.intechopen.com/books/phytochemicalsa-global-perspective-of-their-role-in-nutrition-andhealth/phytochemicals-extractionmethods-basic-structures-and-mode-of-action-as-potentialchemotherapeutic]
]Search in Google Scholar
[
5. Renaud J, Martinol M. Resveratrol as a protective molecule for neuroinflammation: A review of mechanisms. Curr Pharm Biotechnol. 2014;15:1–12.10.2174/1389201015666140617101332
]Search in Google Scholar
[
6. Adesina SK. Constituents of Solanum Dasyphyllum fruit. J Nat Prod. 1985;48(1):147.10.1021/np50037a033
]Search in Google Scholar
[
7. Ali Z, Xu ZL; Zhang DY, He XL, Bahadur L, Yi XY. Molecular diversity analysis of eggplant (Solanum melongena) genetic resources. Genet Mol Res. 2013;10(2):1141–55.10.4238/vol10-2gmr1279
]Search in Google Scholar
[
8. Ajayi IA, Ojelere O. Evaluation of the antimicrobial properties of the ethanolic extracts of some medicinal plant Seeds from South-West Nigeria. IOSR-JPBS. 2014;9(4):80–5.10.9790/3008-09418085
]Search in Google Scholar
[
9. Coune C, Denoel A. Etude phytochimique des solanaceae d’afrique centrale i. Les alcalo~deds e Solanum dasyphyllum. Planta Med. 1975;28:168–71.10.1055/s-0028-1097846
]Search in Google Scholar
[
10. Puy velde LV, Geysen D, Ayobangira F, Nakizamungu E, Nswimiyimana A, Kalisa A. screening of medicinal plants of Rwanda for Acaricidal activity. J Ethnopharmacol. 1985;13:209–15.10.1016/0378-8741(85)90008-X
]Search in Google Scholar
[
11. Clementino-Neto J, Pereira JC, Vasconcelos LHC, de Souza ILL, Silva ADS, Silva TMG, et al. Toxicological, Antidiarrheal, and Spasmolytic Activities of Solanum paniculatum. Planta Med. 2016; 82:58–64.
]Search in Google Scholar
[
12. Obade E, Ilesanmi OB, Crown O, Akinmoladun AC, Olaleye MT, Akindahunsi AA. Neuromodulatory effect of solvent fractions of Africa eggplant (Solanum dadyphyllum) against KCN-induced mitochondria damage, viz. NADH-succinate dehydrogenase, NADH- cytochrome c reductase, and succinate-cytochrome c reductase. Clin Phytosci. 2018;4(9):1–9.
]Search in Google Scholar
[
13. Li X, He G, Mu X, Xu B, Tian S, Yu X, et al. Protective effects of baicalein against rotenone-induced neurotoxicity in PC12 cells and isolated rat brain mitochondria. Eur J Pharmacol. 2012;674:227–33.10.1016/j.ejphar.2011.09.18121996316
]Search in Google Scholar
[
14. Sherer TB, Betarbet R, Testa CM, Seo BB, Richardson JR, Kim JH, et al. Mechanism of toxicity in rotenone models of Parkinson’s disease. J Neurosci. 2003;23(34):10756–64.10.1523/JNEUROSCI.23-34-10756.2003
]Search in Google Scholar
[
15. Swarnkar S, Tyagi E, Agrawal R, Singh MP, Nath C. A comparative study on oxidative stress induced by LPS and rotenone in homogenates of rat brain regions. ETAP. 2009;27:219–24.10.1016/j.etap.2008.10.003
]Search in Google Scholar
[
16. Okhawa H. Assay for lipid peroxide in animal tissues by Thiobarbituric acid reaction. Annu Rev Biochem. 1979;95:351–2.10.1016/0003-2697(79)90738-3
]Search in Google Scholar
[
17. Levine RL, Garland D, Oliver C, Amici A, Climent I, Lenz A. Determination of carbonyl content in oxidatively modified proteins. Methods Enzymol. 1990;186:464–78.10.1016/0076-6879(90)86141-H
]Search in Google Scholar
[
18. Ellman GL, Courtney KD, Andres V, Feather-Stone RM. A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol. 1961;7:88–95.10.1016/0006-2952(61)90145-9
]Search in Google Scholar
[
19. Spinazzi M, Casarin A, Pertegato V, Salviati L, Angelini C. Assessment of mitochondrial respiratory chain enzymatic activities on tissues and cultured cells. Nat Protoc. 2012;7(6):1235–46.10.1038/nprot.2012.05822653162
]Search in Google Scholar
[
20. Kollareth DMJ, Muralidhara M. Neuroprotective efficacy of a combination of Fish oil and Ferulic acid against 3-nitropropionic acid-induced oxidative stress and neurotoxicity in rats: behavioral and biochemical evidence. APNM. 2003;39(4):1–10.
]Search in Google Scholar
[
21. Kchaou W, Abbès F, Blecker C, Attia H, Besbes S. 2013. Effects of extraction solvents on phenolic contents and antioxidant activities of Tunisian date varieties (Phoenix dactylifera L.). Industrial Crops Products. 2013;45:262–9.10.1016/j.indcrop.2012.12.028
]Search in Google Scholar
[
22. Ngo TV, Scarlett CJ, Bowyer MC, Ngo PD, Vuong QV. Impact of different extraction solvents on bioactive compounds and antioxidant capacity from the root of Salacia chinensis L. J Food Qual. 2017;1:1–8.10.1155/2017/9305047
]Search in Google Scholar
[
23. Belwal T, Ezzat SM, Rastrelli L, Bhatt ID, Daglia M, Baldi A, et al. A critical analysis of extraction techniques used for botanicals: trends, priorities, industrial uses, and optimization strategies. TrAC. 2018;100:82–102.10.1016/j.trac.2017.12.018
]Search in Google Scholar
[
24. Dirar AI, Alsaadi DHM, Wada M, Mohamed MA, Watanabe T, Devkota HP. 2019. Effects of extraction solvents on total phenolic and flavonoid contents and biological activities of extracts from Sudanese medicinal plants. S Afr J Bot. 2019;120:261–7.10.1016/j.sajb.2018.07.003
]Search in Google Scholar
[
25. Roddick JG. Steroidal glycoalkaloid nature and sequences of bioactivity. Adv Exp Med Biol. 1996;404:277–95.10.1007/978-1-4899-1367-8_25
]Search in Google Scholar
[
26. Roddick JG, Weissenberg M, Leonard AL. Membrane disruption and enzyme inhibition by naturally-occurring and modified chacotriose-containing Solanum steroidal glycoalkaloids. Phytochemistry. 2001; 56(6):603–10.10.1016/S0031-9422(00)00420-9
]Search in Google Scholar
[
27. Tai BH, Doan VV, Pham Yen PH, Nhiem NX, Cuc NT, Trang DT, et al. Two new steroidal alkaloid saponins from the whole plants of Solanum nigrum. NPC. 2018;13(11):1457–60.10.1177/1934578X1801301111
]Search in Google Scholar
[
28. Shela MK, Patil MJ, Bhujbal SS, Chaudhari RB. Evaluation of the anticonvulsant activity of the ethanolic extracts from leaves of Excoecaria agallocha. FJPS. 2018;4(2):215–9.
]Search in Google Scholar
[
29. Velmurugan BK, Rathinasamy B, Lohanathan BP, Thiyagarajan V, Weng C. Neuroprotective role of phytochemicals. Molecules. 2018; 23(2485):1–15.10.3390/molecules23102485622249930262792
]Search in Google Scholar
[
30. Muralidhara GK. (2013) Neuroprotective effects of tomato seed extract against rotenone-induced oxidative impairments and neurotoxicity in mice. Toxicol Lett. 2013;221(Suppl.):S237.
]Search in Google Scholar
[
31. Sudati JH, Vieira FA, Pavin SS, Mundstock D, Seeger RL, Golombieski R, et al. Valeriana officinalis attenuates the rotenone-induced toxicity in Drosophila melanogaster. Neurotoxicology. 2013;37:118–26.10.1016/j.neuro.2013.04.00623639798
]Search in Google Scholar
[
32. Thakur P, Nehru B. Long-term heat shock proteins (HSPs) induction by carbenoxolone improves hallmark features of Parkinson’s disease in a rotenone-based model. Neuropharmacol. 2013;79C:190–200.10.1016/j.neuropharm.2013.11.01624296154
]Search in Google Scholar
[
33. Betarbet R, Canet-Aviles RM, Sherer TB, Mastroberardino PG, McLendon C, Kim JH, et al. Intersecting pathways to neurodegeneration in Parkinson’s disease: effects of the pesticide rotenone on DJ-1, alpha-synuclein, and the ubiquitin-proteasome system. Neurobiol Dis. 2006;22(2):404–20.10.1016/j.nbd.2005.12.00316439141
]Search in Google Scholar
[
34. Joseph D, Muralidhara KM. Enhanced neuroprotective effect of fish oil in combination with quercetin against3-nitropropionic acid-induced oxidative stress in rat brain. Prog Neuro-Psychopharmacol Biol Psychiatry. 2013;40:83–92.10.1016/j.pnpbp.2012.08.01822960609
]Search in Google Scholar
[
35. Muralidhara CG. Neuroprotective effect of aqueous extract of Selaginella delicatula as evidenced by abrogation of rotenone-induced motor deficits, oxidative dysfunctions, and neurotoxicity in mice. Cell Mol Neurobiol. 2013;33:929–42.10.1007/s10571-013-9959-y23868340
]Search in Google Scholar
[
36. Yankuzo HM, Baraya YS, Mustapha Z, Wong KK, Yaacob NS. Immunomodulatory effects of a bioactive fraction of Strobilanthes crispus in NMU-induced rat mammar y tumor model. J Ethnopharmacol. 2018;213:31–7.10.1016/j.jep.2017.10.02429100935
]Search in Google Scholar
[
37. Liu Z, Zhou T, Ziegler AC, Dimitrion P, Zuo L. Oxidative stress in neurodegenerative diseases: From molecular mechanisms to clinical applications. Oxi Med Cell Longev. 2017;ID 2525967:1–11.10.1155/2017/2525967552966428785371
]Search in Google Scholar
[
38. Moreira PI, Zhu X, Wang X, Lee H, Nunomuro A, Petersen RB, et al. Mitochondria: a therapeutic target in neurodegeneration. BBA. 2010;1802:212–20.10.1016/j.bbadis.2009.10.007279054019853657
]Search in Google Scholar
[
39. Ilesanmi OB, Akinmoladun AC, Olayeriju OS, Saliu IO, Olaleye MT, Akindahunsi AA. Modulation of key biochemical markers relevant to stroke by Antiaris africana leaf extract following cerebral ischemia/reperfusion injury. Afr J Tradit Complement Altern Med. 2017;14(4):253–64.10.21010/ajtcam.v14i4.28547147328638888
]Search in Google Scholar
[
40. Pandey S, Singh B, Khan MMAA, Mahdi AA. Pharmacological profile of Bacopa monnieri: An approach to prevention and treatment of diseases. Herb Med Mod Drug Discovery. 2017;189–204.
]Search in Google Scholar
[
41. Sandler M, Glover S. Neurotoxins and monoamine oxidase B inhibitors: possible mechanisms for the neuroprotective effect of (y¨) deprenyl. Inhibitors of Monoamine Oxidase B.1993:169–81.10.1007/978-3-0348-6348-3_8
]Search in Google Scholar
[
42. Dalle-Donne I, Scaloni A, Giustarini D, Cavarra E, Tell G, Lungarella G, Colombo R, et al. 2005. Proteins as biomarkers of oxidative/nitrosative stress in diseases: the contribution of redox proteomics. Mass Spectrom Rev. 2005;24:55–99.10.1002/mas.2000615389864
]Search in Google Scholar