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High-Resolution HLA-DRB1 Allele Frequencies in a Romanian Cohort of Stem Cell Donors

MA Caragea

MA Caragea

  • Carol Davila University of Medicine and PharmacyBucharest, Romania
  • Center for Immunogenetics and Virology, Fundeni Clinical InstituteBucharest, Romania
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Caragea, MA
, 
IR Ursu

IR Ursu

Carol Davila University of Medicine and Pharmacy, Department of Medical GeneticsBucharest, Romania
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Ursu, IR
, 
DL Visan

DL Visan

Center for Immunogenetics and Virology, Fundeni Clinical InstituteBucharest, Romania
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Visan, DL
, 
I Maruntelu

I Maruntelu

  • Carol Davila University of Medicine and PharmacyBucharest, Romania
  • Center for Immunogenetics and Virology, Fundeni Clinical InstituteBucharest, Romania
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Maruntelu, I
, 
P Iordache

P Iordache

Carol Davila University of Medicine and Pharmacy, Department of EpidemiologyBucharest, Romania
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Iordache, P
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A Constantinescu

A Constantinescu

Carol Davila University of Medicine and PharmacyBucharest, Romania
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Constantinescu, A
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M Tizu

M Tizu

  • Carol Davila University of Medicine and PharmacyBucharest, Romania
  • Center for Immunogenetics and Virology, Fundeni Clinical InstituteBucharest, Romania
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Tizu, M
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A Tălăngescu

A Tălăngescu

  • Carol Davila University of Medicine and PharmacyBucharest, Romania
  • Center for Immunogenetics and Virology, Fundeni Clinical InstituteBucharest, Romania
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Tălăngescu, A
 y 
I Constantinescu

I Constantinescu

  • Carol Davila University of Medicine and PharmacyBucharest, Romania
  • Center for Immunogenetics and Virology, Fundeni Clinical InstituteBucharest, Romania
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Constantinescu, I
  
06 sept 2024
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Categoría del artículo: Original Article
Publicado en línea: 06 sept 2024
Páginas: 43 - 49
DOI: https://doi.org/10.2478/bjmg-2024-0009
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© 2024 MA Caragea et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Figure 1.

HLA-DRB1 alleles with frequencies > 10% (6-digits)
HLA-DRB1 alleles with frequencies > 10% (6-digits)

Figure 2.

Combined HLA-DRB1 allele frequencies (2-digits)
Combined HLA-DRB1 allele frequencies (2-digits)

HLA-DRB1 alleles identified in the Romanian cohort (6-digits)

HLA-DRB1 alleles No. AF (%)
*16:01:01 102 12.59
*11:04:01 98 12.10
*03:01:01 97 11.98
*07:01:01 75 9.26
*01:01:01 59 7.28
*11:01:01 51 6.30
*13:01:01 49 6.05
*15:01:01 35 4.32
*13:02:01 24 2.96
*04:01:01 21 2.59
*04:02:01 17 2.10
*04:03:01 17 2.10
*13:03:01 15 1.85
*14:54:01 15 1.85
*10:01:01 14 1.73
*15:02:01 13 1.60
*04:04:01 11 1.36
*16:02:01 11 1.36
*12:01:01 10 1.23
*08:01:01 9 1.11
*01:02:01 9 1.11
*14:03:01 9 1.11
*14:01:01 9 1.11
*04:05:01 8 0.99
*14:04:01 8 0.99
*11:03:01 6 0.74
*08:03:02 3 0.37
*02:02:01 2 0.25
*11:01:02 1 0.12
*08:04:01 1 0.12
*05:01:01 1 0.12
*13:05:01 1 0.12
*14:07:01 1 0.12
*09:01:02 1 0.12
*11:02:01 1 0.12
*04:07:01 1 0.12
*15:03:01 1 0.12
*03:02:01 1 0.12
*04:06:02 1 0.12
*04:08:01 1 0.12
*14:05:01 1 0.12
Total general 810 100

HLA-DRB1 allele frequencies (2-digits)

HLA-DRB1 alleles AF (%)
DRB1*11 19.38
DRB1*16 13.95
DRB1*03 12.10
DRB1*13 10.99
DRB1*04 9.51
DRB1*07 9.26
DRB1*01 8.40
DRB1*15 5.93
DRB1*14 5.31
DRB1*10 1.73
DRB1*12 1.23
DRB1*02 0.25
DRB1*05 0.12
DRB1*09 0.12
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Medicina, Ciencias médicas básicas, Ciencias médicas básicas, otros
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