[Appendino, G., Mercalli, E., Fuzzati, N., Arnoldi, L., Stavri, M., Gibbons, S., Ballero, M. and Maxia, A., 2004. Antimycobacterial coumarins from the sardinian giant fennel (Ferula communis). J. Nat. Prod., 67(12), 2108-2110.10.1021/np049706n15620264]Search in Google Scholar
[Archer, N., Galacteros, F. and Brugnara, C., 2015. Clinical trials update in sickle cell anemia. Am. J. Hematol., 90(10), 934-950.10.1002/ajh.24116575213626178236]Search in Google Scholar
[Ashley-Koch, A., Yang, Q. and Olney, R.S., 2000. Sickle hemoglobin (Hb S) allele and sickle cell disease: A HuGE review. Am. J. Epidemiol., 151(9), 839-845.10.1093/oxfordjournals.aje.a01028810791557]Search in Google Scholar
[Asif, M., 2015. Pharmacological activities and phytochemistry of various plant containing coumarin derivatives. Curr. Sci. Perspect., 1(3), 77-90.]Search in Google Scholar
[Bernaudin, F., Socie, G., Kuentz, M., Chevret, S., Duval, M. Bertrand, Y., Vannier, J.-P., Yakouben, K., Thuret, I., Bordigoni, P., Fischer, A., Lutz, P., Stephan, J.-L., Dhedin, N., Plouvier, E., Margueritte, G., Bories, D., Verlhac, S., Esperou, H., Coic, L., Vernant, J.-P. and Gluckman, E., 2007. Long-term results of related myeloablative stem-cell transplantation to cure sickle cell disease. Blood, 110(7), 2749-2756.10.1182/blood-2007-03-07966517606762]Search in Google Scholar
[Buchanan, G.R., De Baun, M.R., Quinn, C.T. and Steinberg, M.H., 2004. Sickle cell disease. Hematology, 2004, 35-47.10.1182/asheducation-2004.1.3515561675]Open DOISearch in Google Scholar
[Charache, S., Terrin, M.L., Moore, R.D., Dover, G.J., Barton, F.B., Eckert, S.V., McMahon R.P. and Bonds, D.R., 1995. Effect of hydroxyurea on the frequency of painful crises in Sickle cell anemia. N. Engl. J. Med., 332, 1317-1322.10.1056/NEJM1995051833220017715639]Search in Google Scholar
[Chikezie, P.C., Chikezie, C.M. and Amaragbulem, P.I., 2010. Effect of antimalarial drugs on polymerization of sickle cell hemoglobin (HbS). Turk. J. Biochem., 35(1), 41-44.]Search in Google Scholar
[Dadwal, M., Mohan, R., Panda, D., Mobin, S. M. and Namboothiri, I.N.N., 2006. The Morita–Baylis–Hillman adducts of β-aryl nitroethylenes with other activated alkenes: synthesis and anticancer activity studies. Chem. Comm., 2006, 338-340.10.1039/B512267H16391753]Search in Google Scholar
[Egunyomi, A., Moody, J.O. and Eletu, O.M., 2009. Antisickling activities of two ethnomedicinal plant recipes used for the management of sickle cell anaemia in Ibadan, Nigeria. Afr. J. Biotech., 8(1), 20-25.]Search in Google Scholar
[Haywood, C.M., Beach, C., Bediako, S., Carroll, C. P., Lattimer, L., Jarrett, D. and Lanzkron, S., 2011. Examining the characteristics and beliefs of hydroxyurea users and nonusers among adults with sickle cell disease. Am. J. Hematol., 86(1), 85-87.10.1002/ajh.21883323334921117058]Search in Google Scholar
[He, J.-Y., Zhang, W., He, L.-C. and Cao, Y.-X., 2007. Imperatorin induces vasodilatation possibly via inhibiting voltage dependent calcium channel and receptor-mediated Ca2+ influx and release. Eur. J. Pharmacol., 573, 170-175.10.1016/j.ejphar.2007.06.04317662269]Search in Google Scholar
[Hoban, M.D., Orkin, S.H. and Bauer, D.E., 2016. Genetic treatment of a molecular disorder: gene therapy approaches to sickle cell disease. Blood, 127(7), 839-848.10.1182/blood-2015-09-618587476008926758916]Search in Google Scholar
[Hoult, J.R. and Paya, M., 1996. Pharmacological and biochemical actions of simple coumarins: natural products with therapeutic potential. Gen. Pharmacol., 27, 713-722.10.1016/0306-3623(95)02112-4]Open DOISearch in Google Scholar
[Imaga, N.A., Chukwu, C.E., Blankson, A. and Gbenle, G.O., 2013. Biochemical assessment of Ciklavit®, a nutraceutical used in sickle cell anaemia management. Journal of Herbal Medicine, 3, 137-148.10.1016/j.hermed.2013.05.003]Search in Google Scholar
[Iwu, M.M., Igboko, A.O., Onwubiko, H. and Ndu, U.E., 1988. Effect of cajaminose from Cajanus cajan on gelation and oxygen affinity of sickle cell haemoglobin. J. Ethnopharmacol., 23, 99-104.10.1016/0378-8741(88)90118-3]Open DOISearch in Google Scholar
[Kaye, P.T. and Musa, M.A., 2002. A Convenient and Improved Baylis-Hillman Synthesis of 3-Substituted 2H-1-benzopyran-2-ones. Synthesis, 18, 2701-2706.10.1055/s-2002-35984]Search in Google Scholar
[Kaye, P.T., Musa, M.A. and Nocanda, X.W., 2003. Efficient and chemoselective access to 3-(chloromethyl)coumarins via direct cyclisation of unprotected Baylis–Hillman adducts. Synthesis, 4, 531-534.10.1055/s-2003-37655]Search in Google Scholar
[Kennedy, R.O. and Thornes, R.D. (Eds.). Coumarins: Biology, Applications and Mode of Action. Wiley, New York, 1997.]Search in Google Scholar
[Kidane, A.G., Salacinski, H., Tiwari, A., Bruckdorfer, K.R. and Seifalian, A.M., 2004. Anticoagulant and antiplatelet agents: their clinical and device application(s) together with usages to engineer surfaces. Biomacromolecules, 5, 798-813.10.1021/bm034455315132664]Open DOISearch in Google Scholar
[Kontogiorgis, C.A. and Hadjipavlou, L.D., 2004. Synthesis and biological evaluation of novel coumarin derivatives with a 7-azomethine linkage. Bioorg. Med. Chem. Lett., 14, 611-614.10.1016/j.bmcl.2003.11.06014741253]Open DOISearch in Google Scholar
[Kutlar, A., Ataga, K. and Reid, M., 2012. A phase 1/2 trial of HQK-1001, an oral fetal globin inducer, in sickle cell disease. American. J. Hematol., 87(11), 1017-1021.10.1002/ajh.23306390479222887019]Search in Google Scholar
[Ma, T., Liu, L., Xue, H., Li, L., Han, C., Wang, L., Chen, Z. and Liu, G., 2008. Chemical library and structure-activity relationships of 11-demethyl-12-oxo calanolide A analogues as anti-HIV-1 agents. J. Med. Chem., 51, 1432-1446.10.1021/jm701405p18284187]Search in Google Scholar
[Ma, Y.- L., Rees, D.C., Gibson, J.S. and Ellory, J.C., 2012. The conductance of red blood cells from sickle cell patients: ion selectivity and inhibitors. J. Physiol., 590(9), 2095-2105.10.1113/jphysiol.2012.229609344715322411011]Search in Google Scholar
[Makani, J., Williams, T. N. and Marsh, K., 2013. Sickle cell disease in Africa: burden and research priorities. Ann. Trop. Med. Parasitol., 101(1), 3-14.10.1179/136485907X154638]Search in Google Scholar
[Mehanna, A.S., 2001. Sickle cell anemia and antisickling agents then and now. Current Medicinal Chemistry, 8, 79-88.10.2174/0929867013373778]Search in Google Scholar
[Narender, P., Srinivas, U., Gangadasu, B., Biswas, S. and Rao, V.J., 2005. Anti-malarial activity of Baylis-Hillman adducts from substituted 2-chloronicotinaldehydes. Bioorg. Med. Chem. Lett., 15, 5378-5381.10.1016/j.bmcl.2005.09.008]Open DOISearch in Google Scholar
[Nelson, D.L. and Cox, M.M. Lehninger Principles of Biochemistry. Fourth edition, (2008) pp 75-189. W.H. Freeman, New York.]Search in Google Scholar
[Oder, E., Safo, M.K., Abdulmalik, O. and Kato, G.J., 2016. New Developments in Anti-Sickling Agents: Can Drugs Directly Prevent the Polymerization of Sickle Haemoglobin In Vivo? British Journal of Haematology, 175(1), 24-30.10.1111/bjh.14264]Search in Google Scholar
[Olomola, T.O., Klein, R., Mautsa, N., Sayed, Y. and Kaye, P.T., 2013. Synthesis and evaluation of coumarin derivatives as potential dualaction HIV-1 protease and reverse transcriptase inhibitors. Bioorg. Med. Chem., 21, 1964-1971.10.1016/j.bmc.2013.01.025]Search in Google Scholar
[Olomola, T.O., Mosebi, S., Klein, R., Traut-Johnstone, T., Coates, J., Hewer, R. and Kaye P.T., 2014. Novel furocoumarins as potential HIV-1 integrase inhibitors. Bioorg. Chem., 57, 1-4.10.1016/j.bioorg.2014.07.008]Search in Google Scholar
[Panepinto, J.A., Walters, M.C., Carreras, J., Marsh, J., Bredeson, C.N., Gale, R.P., Hale, G.A., Horan, J., Hows, J.M., Klein, J.P., Pasquini, R., Roberts, I., Sullivan, K., Eapen, M. and Ferster, A., 2007. Matched-related donor transplantation for sickle cell disease: report from the Center for International Blood and Transplant Research. Brit. J. Haematol., 137, 479-485.10.1111/j.1365-2141.2007.06592.x]Search in Google Scholar
[Rashamuse, T.J., Musa, M.A., Klein, R. and Kaye, P.T., 2009. Regiocontrolled Michaelis–Arbuzov reactions of 3-(halomethyl)-coumarins. J. Chem. Res., 5, 302-305.10.3184/030823409X439708]Open DOISearch in Google Scholar
[Saraceno, R., Teoli, M. and Chimenti, S., 2008. Hydroxyurea associated with concomitant occurrence of diffuse longitudinal melanonychia and multiple squamous cell carcinomas in an elderly subject. Clin. Ther., 30(7), 1324-1329.10.1016/S0149-2918(08)80057-4]Open DOISearch in Google Scholar
[Steinberg, M.H., 1999. Management of sickle cell disease. N. Engl. J. Med., 340(13), 1021-1030.10.1056/NEJM19990401340130710099145]Search in Google Scholar
[Vasconcellos, M.L.A.A., Silva, T.M.S., Camara, C.A., Martins, R.M., Lacerda, K.M., Lopes, H.M., Pereira, V.L.P., de Souza, R.O.M.A. and Crespo, L.T.C., 2006. Baylis–Hillman adducts with molluscicidal activity against Biomphalaria glabrata. Pest Managment Science, 62, 288-292.10.1002/ps.115316475220]Search in Google Scholar
[Yang, Y.Z., Ranz, A., Pan, H.Z., Zhang, Z.N., Lin, X. B. and Meshnick, S.R., 1992. Daphnetin: a novel antimalarial agent with in vitro and in vivo activity. Am. J. Trop. Med. Hyg., 46, 15-20.10.4269/ajtmh.1992.46.151311154]Open DOISearch in Google Scholar