<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>The recent pandemic stress and the impacts of climatic changes on humans’ and animals’ health status and well-being resulted in severe drawbacks. Initially, stress-induced oxidation resulting from the generation of free radicals led to the impairment of cellular function and a high possibility of attack with infection. Astaxanthin is a bioactive material derived from fish, crustaceans, and algae with high antioxidative potential. Astaxanthin is a lipid-soluble carotenoid that can easily cross through the cellular membrane layers to catch the reactive oxygen metabolites. Astaxanthin also has pigmentation properties making it suitable for pharmaceutical, cosmetic, nutraceutical, agriculture, and aquaculture sectors. Recently, astaxanthin is suggested as a natural scavenger for free radicals induced by COVID-19. Besides, using astaxanthin as antioxidative and immunostimulant agents is well-reported in several clinical studies. The output of these investigations should be simplified and presented to the scientific community to utilize the available information and fill the gap of knowledge. Also, it is necessary to update the researchers with the recent recommendations of applying astaxanthin <italic>in vivo</italic> and <italic>in vitro</italic> to help in proposing new horizons for engaging natural antioxidative agents to protect human and animal health. Herein, this review article tackled the nature, sources, potential roles, applicable sides, and availability of astaxanthin to fortify the scientific community with the required knowledge for further research efforts.</p>
</abstract>

The recent pandemic stress and the impacts of climatic changes on humans’ and animals’ health status and well-being resulted in severe drawbacks. Initially, stress-induced oxidation resulting from the generation of free radicals led to the impairment of cellular function and a high possibility of attack with infection. Astaxanthin is a bioactive material derived from fish, crustaceans, and algae with high antioxidative potential. Astaxanthin is a lipid-soluble carotenoid that can easily cross through the cellular membrane layers to catch the reactive oxygen metabolites. Astaxanthin also has pigmentation properties making it suitable for pharmaceutical, cosmetic, nutraceutical, agriculture, and aquaculture sectors. Recently, astaxanthin is suggested as a natural scavenger for free radicals induced by COVID-19. Besides, using astaxanthin as antioxidative and immunostimulant agents is well-reported in several clinical studies. The output of these investigations should be simplified and presented to the scientific community to utilize the available information and fill the gap of knowledge. Also, it is necessary to update the researchers with the recent recommendations of applying astaxanthin in vivo and in vitro to help in proposing new horizons for engaging natural antioxidative agents to protect human and animal health. Herein, this review article tackled the nature, sources, potential roles, applicable sides, and availability of astaxanthin to fortify the scientific community with the required knowledge for further research efforts.

Pharmacotherapeutic potential of astaxanthin: Human and animal targeting roles – A review

Animal Production Department, Faculty of Agriculture

Department of Animal and Aquatic Sciences, Faculty of Agriculture

Annals of Animal Science

This work is licensed under the Creative Commons Attribution 4.0 International License.

The recent pandemic stress and the impacts of climatic changes on humans’ and animals’ health status and well-being resulted in severe drawbacks. Initially,...

Pharmacotherapeutic potential of astaxanthin: Human and animal targeting roles – A review

Publicado en línea: 19 jul 2022

Páginas: 829 - 838

Recibido: 18 nov 2021

Aceptado: 31 ene 2022

DOI: https://doi.org/10.2478/aoas-2022-0017

Palabras clave
astaxanthin, human health, animal welfare, well-being, immuno-therapy, immuno-nutrition

© 2022 Mohammed F. El Basuini et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Pharmacotherapeutic potential of astaxanthin: Human and animal targeting roles – A review

Publicado en línea: 19 jul 2022

Páginas: 829 - 838

Recibido: 18 nov 2021

Aceptado: 31 ene 2022

DOI: https://doi.org/10.2478/aoas-2022-0017

Palabras claveastaxanthin, human health, animal welfare, well-being, immuno-therapy, immuno-nutrition

© 2022 Mohammed F. El Basuini et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Palabras clave
astaxanthin, human health, animal welfare, well-being, immuno-therapy, immuno-nutrition