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This paper reports the research results on the target group survey at European level, composed of manufacturing SMEs and VET regarding knowledge and skills gaps about Industry 4.0, namely knowledge and skills gaps. It sets the basis for elaboration of the of a training course and a practical methodology for web based learning in accordance with the target groups’ needs as well as to provide basis for forming recommendations for evidencebased policy in the field of web based learning. The suggested training modules are: Introduction to Industry 4.0; Solutions for smart production environments in the manufacturing sector; Smart robotics; and Application of CPS/IoT across the process chain. The preferences according to the technological solutions/functions in an interactive educational website are highlighted as well as the proportion of theory and practical on the job training when organizing web based learning in the field of Industry 4.0.