[1. Rawat DK, Alzoubi A, Gupte R, et al. Increasedreactive oxygen species, metabolic maladaptation, and autophagy contribute to pulmonaryarterial hypertension-induced ventricular hypertrophy and diastolic heart failure. Hypertension. 2014; 64:1266-1274.10.1161/HYPERTENSIONAHA.114.0326125267798]Search in Google Scholar
[2. Hilde JM, Skjørten I, Hansteen V, et al. Haemodynamic responses to exercise in patients with COPD. Eur Respir J. 2013;41(5):1031-41.10.1183/09031936.0008561222903957]Search in Google Scholar
[3. Toraldo D, Minelli M, De Nuccio, Chronic obstructive pulmonarydiseasephenotype desaturator with hypoxic vascularremodelling and pulmonaryhypertensionobtained by cluster analysis Multidisciplinary Respiratory Medicine. 2012, 7:39-49.10.4081/mrm.2012.626]Search in Google Scholar
[4. Chaouat A, Naeije R, Weitzenblum E. Pulmonary hypertension in COPD. Eur Respir J. 2008;32(5):1371-85.10.1183/09031936.0001560818978137]Search in Google Scholar
[5. Badesch DB, Champion HC, Sanchez MA, et al.Diagnosis and assessment of pulmonary arterial hypertension. J Am Coll Cardiol. 2009;54:S55-66.10.1016/j.jacc.2009.04.01119555859]Search in Google Scholar
[6. Thabut G, Dauriat G, Stern JB, et al. Pulmonaryhemodynamics in advanced COPD candidates for lung volume reduction surgery or lungtransplantation. Chest. 2005;127: 1531–1536.10.1378/chest.127.5.153115888824]Search in Google Scholar
[7. Iyer AS, Wells JM, Vishin S, et al. CT scan-measuredpulmonary artery to aorta ratio and echocardiography for detecting pulmonary hypertension insevere COPD. Chest. 2014;145(4):824-832.10.1378/chest.13-1422397197124114440]Search in Google Scholar
[8. Peacock AJ, Crawley S, McLure L. Changes in right ventricular function measured bycardiac magnetic resonace imaging in patients receiving pulmonary arterial hypertensiontargeted therapy the Euro MR study. Circ Cardiovasc Imaging. 2014:7;107-14.10.1161/CIRCIMAGING.113.00062924173272]Search in Google Scholar
[9. Cuttica MJ, Shah SJ, Rosenberg SR, et al. Right heartstructural changes are independently associated with exercise capacity in non-severe COPD. PLoS One. 2011; 6:e29069.10.1371/journal.pone.0029069324840422220201]Search in Google Scholar
[10. Lancellotti P, Moura L, Pierard LA, et al. European Association of Echocardiography European Association of Echocardiography recommendations for the assessment of valvular regurgitation. Part 2: mitral and tricuspidregurgitation (native valve disease). Eur J Echocardiogr. 2010;11(4):307-32.10.1093/ejechocard/jeq03120435783]Search in Google Scholar
[11. Mezzani A, Agostoni P, Cohen-Solal A. Standards for the use of cardiopulmonary exercise testing for thefunctional evaluation of cardiac patients: A report from 76 European Journal of Preventive Cardiology 23(1) the Exercise Physiology Section of theEuropeanAssociation for Cardiovascular Prevention and Rehabilitation. Eur J Cardiov Prev R.2009; 16: 249-267.10.1097/HJR.0b013e32832914c819440156]Search in Google Scholar
[12. Kovacs G, Berghold A, Scheidl S, et al. Pulmonary arterial pressure during restand exercise in healthy subjects: a systematic review. Eur Respir J. 2009;34:888-94.10.1183/09031936.0014560819324955]Search in Google Scholar
[13. Galiè N, Humbert M, Vachiery JL, et al. ESC Scientific Document Group. 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European RespiratorySociety (ERS): Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation (ISHLT). Eur Heart J.2016:1;37(1):67-119.]Search in Google Scholar
[14. Rudski LG, Lai WW, Afilalo J, et al. Guidelines for the echo-cardiographic assessment of the right heart in adults: a report from the American Society of Echocardiography endorsed by the European Association of Echocardiography, a registered branch of the European Society of Cardiology, and the Canadian Society of Echocardiography. J Am Soc Echocardiog. 2010;23(7):685-713.10.1016/j.echo.2010.05.01020620859]Search in Google Scholar
[15. Cioffi G, de Simone G, Mureddu G, et al. Right atrial size andfunctionin patients with pulmonary hypertension associated with disorders of respiratorysystemor hypoxemia. Eur J Echocardiogr. 2007;8:322-31.10.1016/j.euje.2006.06.00616876482]Search in Google Scholar
[16. Agoston-Coldea, Dana Petrovai D, Mihalcea I, et al. Right Atrium Volume Index in Patients with Secondary Pulmonary Hypertension Due to Chronic Obstructive Pulmonary Disease. Acta Cardiol Sin. 2015;31:325-336.]Search in Google Scholar
[17. Schoos M, Dalsgaard M, Kjærgaar D J, et al. Echocardio-graphic predictors of exercise capacity and mortality in chronic obstructive pulmonary disease. BMC Cardiovascular Disorders. 2013, 13:84.10.1186/1471-2261-13-84385230624118827]Search in Google Scholar
[18. Gökdeniz T, Kalaycıoğlu E, Boyacı F, et al. TheBODE index, a multidimensional grading system, reflects impairment of right ventriclefunctions in patients with chronic obstructive pulmonary disease: a speckle-tracking study. Respiration. 2014;88(3):223-33.10.1159/00036522225139573]Search in Google Scholar