This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.
Li J-H, Vicknasingam B, Cheung Y, Zhou W, Nurhidayat AW, Jarlais DC Des, Schottenfeld R. To use or not to use: an update on licit and illicit ketamine use. Subst Abuse Rehabil 2011;2:11–20. doi: 10.2147/sar.s15458LiJ-HVicknasingamBCheungYZhouWNurhidayatAWJarlaisDC DesSchottenfeldR. To use or not to use: an update on licit and illicit ketamine use. Subst Abuse Rehabil2011;2:11–20. doi: 10.2147/sar.s15458Open DOISearch in Google Scholar
Negrusz A, Gaensslen RE. Analytical developments in toxicological investigation of drug-facilitated sexual assault. Anal Bioanal Chem 2003;376:1192–7. doi: 10.1007/s00216-003-1896-zNegruszAGaensslenRE. Analytical developments in toxicological investigation of drug-facilitated sexual assault. Anal Bioanal Chem2003;376:1192–7. doi: 10.1007/s00216-003-1896-zOpen DOISearch in Google Scholar
Liu F, Patterson TA, Sadovova N, Zhang X, Liu S, Zou X, Hanig JP, Paule MG, Slikker W, Wang C. Ketamine-induced neuronal damage and altered N-methyl-d-aspartate receptor function in rat primary forebrain culture. Toxicol Sci 2013;131:548–57. doi: 10.1093/toxsci/kfs296LiuFPattersonTASadovovaNZhangXLiuSZouXHanigJPPauleMGSlikkerWWangC. Ketamine-induced neuronal damage and altered N-methyl-d-aspartate receptor function in rat primary forebrain culture. Toxicol Sci2013;131:548–57. doi: 10.1093/toxsci/kfs296Open DOISearch in Google Scholar
Flood P, Krasowski MD. Intravenous anesthetics differentially modulate ligand-gated ion channels. Anesthesiology 2000;92:1418–25. doi: 10.1097/00000542-200005000-00033FloodPKrasowskiMD. Intravenous anesthetics differentially modulate ligand-gated ion channels. Anesthesiology2000;92:1418–25. doi: 10.1097/00000542-200005000-00033Open DOISearch in Google Scholar
Little B, Chang T, Chucot L, Dill WA, Enrile LL, Glazko AJ, Jassani M, Kretchmer H, Sweet AY. Study of ketamine as an obstetric anesthetic agent. Am J Obstet Gynecol 1972;113:247–60. doi: 10.1016/0002-9378(72)90774-0LittleBChangTChucotLDillWAEnrileLLGlazkoAJJassaniMKretchmerHSweetAY. Study of ketamine as an obstetric anesthetic agent. Am J Obstet Gynecol1972;113:247–60. doi: 10.1016/0002-9378(72)90774-0Open DOISearch in Google Scholar
Zanos P, Moaddel R, Morris PJ, Riggs LM, Highland JN, Georgiou P, Pereira EFR, Albuquerque EX, Thomas CJ, Zarate CA, Gould TD. Ketamine and ketamine metabolite pharmacology: Insights into therapeutic mechanisms. Pharmacol Rev 2018;70:621–60. doi: 10.1124/pr.117.015198ZanosPMoaddelRMorrisPJRiggsLMHighlandJNGeorgiouPPereiraEFRAlbuquerqueEXThomasCJZarateCAGouldTD. Ketamine and ketamine metabolite pharmacology: Insights into therapeutic mechanisms. Pharmacol Rev2018;70:621–60. doi: 10.1124/pr.117.015198Open DOISearch in Google Scholar
Mion G, Villevieille T. Ketamine pharmacology: An update (pharmacodynamics and molecular aspects, recent findings). CNS Neurosci Ther 2013;19:370–80. doi: 10.1111/cns.12099MionGVillevieilleT. Ketamine pharmacology: An update (pharmacodynamics and molecular aspects, recent findings). CNS Neurosci Ther2013;19:370–80. doi: 10.1111/cns.12099Open DOISearch in Google Scholar
Hirota K, Sikand KS, Lambert DG. Interaction of ketamine with μ2 opioid receptors in SH-SY5Y human neuroblastoma cells. J Anesth 1999;13:107–9. doi: 10.1007/s005400050035HirotaKSikandKSLambertDG. Interaction of ketamine with μ2 opioid receptors in SH-SY5Y human neuroblastoma cells. J Anesth1999;13:107–9. doi: 10.1007/s005400050035Open DOISearch in Google Scholar
Friederich P, Dybek A, Urban BW. Stereospecific interaction of ketamine with nicotinic acetylcholine receptors in human sympathetic ganglion-like SH-SY5Y cells. Anesthesiology 2000;93:818–24. doi: 10.1097/00000542-200009000-00032FriederichPDybekAUrbanBW. Stereospecific interaction of ketamine with nicotinic acetylcholine receptors in human sympathetic ganglion-like SH-SY5Y cells. Anesthesiology2000;93:818–24. doi: 10.1097/00000542-200009000-00032Open DOISearch in Google Scholar
Choi JM, Oh SJ, Lee SY, Im JH, Oh JM, Ryu CS, Kwak HC, Lee JY, Kang KW, Kim SK. HepG2 cells as an in vitro model for evaluation of cytochrome P450 induction by xenobiotics. Arch Pharm Res 2015;38:691–704. doi: 10.1007/s12272-014-0502-6ChoiJMOhSJLeeSYImJHOhJMRyuCSKwakHCLeeJYKangKWKimSK. HepG2 cells as an in vitro model for evaluation of cytochrome P450 induction by xenobiotics. Arch Pharm Res2015;38:691–704. doi: 10.1007/s12272-014-0502-6Open DOISearch in Google Scholar
Mak YT, Lam WP, Lü L, Wong YW, Yew DT. The toxic effect of ketamine on SH-SY5Y neuroblastoma cell line and human neuron. Microsc Res Tech 2010;73:195–201. doi: 10.1002/jemt.20774MakYTLamWPLüLWongYWYewDT. The toxic effect of ketamine on SH-SY5Y neuroblastoma cell line and human neuron. Microsc Res Tech2010;73:195–201. doi: 10.1002/jemt.20774Open DOISearch in Google Scholar
Nagarajan SR, Paul-Heng M, Krycer JR, Fazakerley DJ, Sharland AF, Hoy XAJ. Lipid and glucose metabolism in hepatocyte cell lines and primary mouse hepatocytes: A comprehensive resource for in vitro studies of hepatic metabolism. Am J Physiol - Endocrinol Metab 2019;316:E578–89. doi: 10.1152/ajpendo.00365.2018NagarajanSRPaul-HengMKrycerJRFazakerleyDJSharlandAFHoyXAJ. Lipid and glucose metabolism in hepatocyte cell lines and primary mouse hepatocytes: A comprehensive resource for in vitro studies of hepatic metabolism. Am J Physiol - Endocrinol Metab2019;316:E578–89. doi: 10.1152/ajpendo.00365.2018Open DOISearch in Google Scholar
Bustamante J, Acosta L, Karadayian AG, Lores-Arnaiz S. Ketamine induced cell death can be mediated by voltage dependent calcium channels in PC12 cells. Exp Mol Pathol 2019;111:104318. doi: 10.1016/j.yexmp.2019.104318BustamanteJAcostaLKaradayianAGLores-ArnaizS. Ketamine induced cell death can be mediated by voltage dependent calcium channels in PC12 cells. Exp Mol Pathol2019;111:104318. doi: 10.1016/j.yexmp.2019.104318Open DOISearch in Google Scholar
Zandona A, Katalinić M, Šinko G, Radman Kastelic A, Primožič I, Kovarik Z. Targeting organophosphorus compounds poisoning by novel quinuclidine-3 oximes: development of butyrylcholinesterase-based bioscavengers. Arch Toxicol 2020;94:3157–71. doi: 10.1007/s00204-020-02811-5ZandonaAKatalinićMŠinkoGRadman KastelicAPrimožičIKovarikZ. Targeting organophosphorus compounds poisoning by novel quinuclidine-3 oximes: development of butyrylcholinesterase-based bioscavengers. Arch Toxicol2020;94:3157–71. doi: 10.1007/s00204-020-02811-5Open DOISearch in Google Scholar
Tice RR, Agurell E, Anderson D, Burlinson B, Hartmann A, Kobayashi H, Miyamae Y, Rojas E, Ryu JC, Sasaki YF. Single cell gel/comet assay: Guidelines for in vitro and in vivo genetic toxicology testing. Environ Mol Mutagen 2000;35:206–21. doi: 10.1002/(SICI)1098-2280(2000)35:3<206::AID-EM8>3.0.CO;2-JTiceRRAgurellEAndersonDBurlinsonBHartmannAKobayashiHMiyamaeYRojasERyuJCSasakiYF. Single cell gel/comet assay: Guidelines for in vitro and in vivo genetic toxicology testing. Environ Mol Mutagen2000;35:206–21. doi: 10.1002/(SICI)1098-2280(2000)35:3<206::AID-EM8>3.0.CO;2-JOpen DOISearch in Google Scholar
Singh NP, McCoy MT, Tice RR, Schneider EL. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp Cell Res 1988;175:184–91. doi: 10.1016/0014-4827(88)90265-0SinghNPMcCoyMTTiceRRSchneiderEL. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp Cell Res1988;175:184–91. doi: 10.1016/0014-4827(88)90265-0Open DOISearch in Google Scholar
Kruszewski M, Sikorska K, Meczynska-Wielgosz S, Grzelak A, Sramkova M, Gabelova A, Kapka-Skrzypczak L. Comet assay in neural cells as a tool to monitor DNA damage induced by chemical or physical factors relevant to environmental and occupational exposure. Mutat Res Genet Toxicol Environ Mutagen 2019;845:402990. doi: 10.1016/j.mrgentox.2018.11.014KruszewskiMSikorskaKMeczynska-WielgoszSGrzelakASramkovaMGabelovaAKapka-SkrzypczakL. Comet assay in neural cells as a tool to monitor DNA damage induced by chemical or physical factors relevant to environmental and occupational exposure. Mutat Res Genet Toxicol Environ Mutagen2019;845:402990. doi: 10.1016/j.mrgentox.2018.11.014Open DOISearch in Google Scholar
Jurič A, Zandona A, Lovaković BT, Rašić D, Pizent A, Kozina G, Katalinić M, Lucić Vrdoljak A, Karačonji IB. Cytotoxic, genotoxic, and oxidative stress-related effects of lysergic acid diethylamide (LSD) and phencyclidine (PCP) in the human neuroblastoma SH-SY5Y cell line. Arh Hig Rada Toksikol 2021;72:333–42. doi: 10.2478/aiht-2021-72-3604JuričAZandonaALovakovićBTRašićDPizentAKozinaGKatalinićMLucić VrdoljakAKaračonjiIB. Cytotoxic, genotoxic, and oxidative stress-related effects of lysergic acid diethylamide (LSD) and phencyclidine (PCP) in the human neuroblastoma SH-SY5Y cell line. Arh Hig Rada Toksikol2021;72:333–42. doi: 10.2478/aiht-2021-72-3604Open DOISearch in Google Scholar
Khoschsorur GA, Winklhofer-Roob BM, Rabl H, Auer T, Peng Z, Schaur R. Evaluation of a sensitive HPLC method for the determination of malondialdehyde, and application of the method to different biological materials. Chromatographia 2000;52:181–4. doi: 10.1007/BF02490453KhoschsorurGAWinklhofer-RoobBMRablHAuerTPengZSchaurR. Evaluation of a sensitive HPLC method for the determination of malondialdehyde, and application of the method to different biological materials. Chromatographia2000;52:181–4. doi: 10.1007/BF02490453Open DOISearch in Google Scholar
Griffiths SM, Singh N, Jenkins GJS, Williams PM, Orbaek AW, Barron AR, Wright CJ, Doak SH. Dextran coated ultrafine superparamagnetic iron oxide nanoparticles: compatibility with common fluorometric and colorimetric dyes. Anal Chem 2011;83:3778–85. doi: 10.1021/ac200103xGriffithsSMSinghNJenkinsGJSWilliamsPMOrbaekAWBarronARWrightCJDoakSH. Dextran coated ultrafine superparamagnetic iron oxide nanoparticles: compatibility with common fluorometric and colorimetric dyes. Anal Chem2011;83:3778–85. doi: 10.1021/ac200103xOpen DOISearch in Google Scholar
Kamencic H, Lyon A, Paterson PG, Juurlink BHJ. Monochlorobimane fluorometric method to measure tissue glutathione. Anal Biochem 2000;286:35–7. doi: 10.1006/abio.2000.4765KamencicHLyonAPatersonPGJuurlinkBHJ. Monochlorobimane fluorometric method to measure tissue glutathione. Anal Biochem2000;286:35–7. doi: 10.1006/abio.2000.4765Open DOISearch in Google Scholar
Cayman Chemical Company. Glutathione Peroxidase Assay Kit [displayed 8 February 2023]. Available at https://www.caymanchem.com/product/703102/glutathione-peroxidase-assay-kitCayman Chemical Company. Glutathione Peroxidase Assay Kit [displayed 8 February 2023]. Available at https://www.caymanchem.com/product/703102/glutathione-peroxidase-assay-kitSearch in Google Scholar
Cayman Chemical Company. Superoxide Dismutase Assay Kit [displayed 8 February 2023]. Available at https://www.caymanchem.com/product/706002/superoxide-dismutase-assay-kitCayman Chemical Company. Superoxide Dismutase Assay Kit[displayed 8 February 2023]. Available at https://www.caymanchem.com/product/706002/superoxide-dismutase-assay-kitSearch in Google Scholar
Cayman Chemical Company. Catalase Assay Kit [displayed 8 February 2023]. Available at https://www.caymanchem.com/product/707002/catalase-assay-kitCayman Chemical Company. Catalase Assay Kit[displayed 8 February 2023]. Available at https://www.caymanchem.com/product/707002/catalase-assay-kitSearch in Google Scholar
Liang Z, Yin P, Zhao L. Effects of combined toxicity of methamphetamine and ketamine on apoptosis, oxidative stress and genotoxicity in HepG2 cells. Food Chem Toxicol 2019;132:110653. doi: 10.1016/j.fct.2019.110653LiangZYinPZhaoL. Effects of combined toxicity of methamphetamine and ketamine on apoptosis, oxidative stress and genotoxicity in HepG2 cells. Food Chem Toxicol2019;132:110653. doi: 10.1016/j.fct.2019.110653Open DOISearch in Google Scholar
Slikker W Jr, Liu F, Rainosek SW, Patterson TA, Sadovova N, Hanig JP, Paule MG, Wang C. Ketamine-induced toxicity in neurons differentiated from neural stem cells. Mol Neurobiol 2015;52:959–69. doi: 10.1007/s12035-015-9248-5SlikkerWJrLiuFRainosekSWPattersonTASadovovaNHanigJPPauleMGWangC. Ketamine-induced toxicity in neurons differentiated from neural stem cells. Mol Neurobiol2015;52:959–69. doi: 10.1007/s12035-015-9248-5Open DOISearch in Google Scholar
Barr CA, Alvarado F, Chang YM, Luo J, Garden OA. The impact of alfaxalone, propofol and ketamine on canine peripheral blood lymphocyte cytotoxicity in vitro. Res Vet Sci 2021;136:182–4. doi: 10.1016/j.rvsc.2021.02.019BarrCAAlvaradoFChangYMLuoJGardenOA. The impact of alfaxalone, propofol and ketamine on canine peripheral blood lymphocyte cytotoxicity in vitro. Res Vet Sci2021;136:182–4. doi: 10.1016/j.rvsc.2021.02.019Open DOISearch in Google Scholar
Koppen G, Azqueta A, Pourrut B, Brunborg G, Collins AR, Langie SAS. The next three decades of the comet assay: A report of the 11th International Comet Assay Workshop. Mutagenesis 2017;32:397–408. doi: 10.1093/mutage/gex002KoppenGAzquetaAPourrutBBrunborgGCollinsARLangieSAS. The next three decades of the comet assay: A report of the 11th International Comet Assay Workshop. Mutagenesis2017;32:397–408. doi: 10.1093/mutage/gex002Open DOISearch in Google Scholar
Collins A, Møller P, Gajski G, Vodenková S, Abdulwahed A, Anderson D, Bankoglu EE, Bonassi S, Boutet-Robinet E, Brunborg G, Chao C, Cooke MS, Costa C, Costa S, Dhawan A, de Lapuente J, Bo’ C Del, Dubus J, Dusinska M, Duthie SJ, Yamani NE, Engelward B, Gaivão I, Giovannelli L, Godschalk R, Guilherme S, Gutzkow KB, Habas K, Hernández A, Herrero O, Isidori M, Jha AN, Knasmüller S, Kooter IM, Koppen G, Kruszewski M, Ladeira C, Laffon B, Larramendy M, Hégarat LL, Lewies A, Lewinska A, Liwszyc GE, de Cerain AL, Manjanatha M, Marcos R, Milić M, de Andrade VM, Moretti M, Muruzabal D, Novak M, Oliveira R, Olsen AK, Owiti N, Pacheco M, Pandey AK, Pfuhler S, Pourrut B, Reisinger K, Rojas E, Rundén-Pran E, Sanz-Serrano J, Shaposhnikov S, Sipinen V, Smeets K, Stopper H, Teixeira JP, Valdiglesias V, Valverde M, van Acker F, van Schooten FJ, Vasquez M, Wentzel JF, Wnuk M, Wouters A, Žegura B, Zikmund T, Langie SAS, Azqueta A. Measuring DNA modifications with the comet assay: a compendium of protocols. Nat Protoc 2023;18:929–89. doi: 10.1038/s41596-022-00754-yCollinsAMøllerPGajskiGVodenkováSAbdulwahedAAndersonDBankogluEEBonassiSBoutet-RobinetEBrunborgGChaoCCookeMSCostaCCostaSDhawanAde LapuenteJBo’C DelDubusJDusinskaMDuthieSJYamaniNEEngelwardBGaivãoIGiovannelliLGodschalkRGuilhermeSGutzkowKBHabasKHernándezAHerreroOIsidoriMJhaANKnasmüllerSKooterIMKoppenGKruszewskiMLadeiraCLaffonBLarramendyMHégaratLLLewiesALewinskaALiwszycGEde CerainALManjanathaMMarcosRMilićMde AndradeVMMorettiMMuruzabalDNovakMOliveiraROlsenAKOwitiNPachecoMPandeyAKPfuhlerSPourrutBReisingerKRojasERundén-PranESanz-SerranoJShaposhnikovSSipinenVSmeetsKStopperHTeixeiraJPValdiglesiasVValverdeMvan AckerFvan SchootenFJVasquezMWentzelJFWnukMWoutersAŽeguraBZikmundTLangieSASAzquetaA. Measuring DNA modifications with the comet assay: a compendium of protocols. Nat Protoc2023;18:929–89. doi: 10.1038/s41596-022-00754-yOpen DOISearch in Google Scholar
Gajski G, Gerić M, Živković Semren T, Tariba Lovaković B, Oreščanin V, Pizent A. Application of the comet assay for the evaluation of DNA damage from frozen human whole blood samples: Implications for human biomonitoring. Toxicol Lett 2020;319:58–65. doi: 10.1016/j.toxlet.2019.11.010GajskiGGerićMŽivković SemrenTTariba LovakovićBOreščaninVPizentA. Application of the comet assay for the evaluation of DNA damage from frozen human whole blood samples: Implications for human biomonitoring. Toxicol Lett2020;319:58–65. doi: 10.1016/j.toxlet.2019.11.010Open DOISearch in Google Scholar
Collins AR. The comet assay for DNA damage and repair: principles, applications, and limitations. Mol Biotechnol 2004;26:249–61. doi: 10.1385/MB:26:3:249CollinsAR. The comet assay for DNA damage and repair: principles, applications, and limitations. Mol Biotechnol2004;26:249–61. doi: 10.1385/MB:26:3:249Open DOISearch in Google Scholar
Asghary M, Raoof JB, Ojani R, Hamidi-Asl E. A genosensor based on CPE for study the interaction between ketamine as an anesthesia drug with DNA. Int J Biol Macromol 2015;80:512–9. doi: 10.1016/j.ijbiomac.2015.07.019AsgharyMRaoofJBOjaniRHamidi-AslE. A genosensor based on CPE for study the interaction between ketamine as an anesthesia drug with DNA. Int J Biol Macromol2015;80:512–9. doi: 10.1016/j.ijbiomac.2015.07.019Open DOISearch in Google Scholar
Lenglet G, David-Cordonnier MH. DNA-destabilizing agents as an alternative approach for targeting DNA: mechanisms of action and cellular consequences. J Nucleic Acids 2010;2010:290935. doi: 10.4061/2010/290935LengletGDavid-CordonnierMH. DNA-destabilizing agents as an alternative approach for targeting DNA: mechanisms of action and cellular consequences. J Nucleic Acids2010;2010:290935. doi: 10.4061/2010/290935Open DOISearch in Google Scholar
Mišković K, Bujak M, Baus Lončar M, Glavaš-Obrovac L. Antineoplastic DNA-binding compounds: intercalating and minor groove binding drugs. Arh Hig Rada Toksikol 2013;64:593–602. doi: 10.2478/10004-1254-64-2013-2371MiškovićKBujakMBaus LončarMGlavaš-ObrovacL. Antineoplastic DNA-binding compounds: intercalating and minor groove binding drugs. Arh Hig Rada Toksikol2013;64:593–602. doi: 10.2478/10004-1254-64-2013-2371Open DOISearch in Google Scholar
Azqueta A, Collins AR. The essential comet assay: a comprehensive guide to measuring DNA damage and repair. Arch Toxicol 2013;87:949–68. doi: 10.1007/s00204-013-1070-0AzquetaACollinsAR. The essential comet assay: a comprehensive guide to measuring DNA damage and repair. Arch Toxicol2013;87:949–68. doi: 10.1007/s00204-013-1070-0Open DOISearch in Google Scholar
Cavalcanti BC, de Andrade Neto JB, de Sousa Silva AA, Barreto FS, de Oliveira Ferreira JR, da Silva CR, Aires do Nascimento FBS, do Amaral Valente Sá LG, Magalhães HIF, Nobre Júnior HV, de Moraes MO. Evaluation of genotoxicity and mutagenicity of ketamine on human peripheral blood leukocytes and in Salmonella typhimurium. Toxicol in Vitro 2020;62:104718. doi: 10.1016/j.tiv.2019.104718CavalcantiBCde Andrade NetoJBde Sousa SilvaAABarretoFSde Oliveira FerreiraJRda SilvaCRAires do NascimentoFBSdo Amaral Valente SáLGMagalhãesHIFNobre JúniorHVde MoraesMO. Evaluation of genotoxicity and mutagenicity of ketamine on human peripheral blood leukocytes and in Salmonella typhimurium. Toxicol in Vitro2020;62:104718. doi: 10.1016/j.tiv.2019.104718Open DOISearch in Google Scholar
Ergün Y, Darendeli S, Imrek S, Kilinç M, Öksüz H. The comparison of the effects of anesthetic doses of ketamine, propofol, and etomidate on ischemia-reperfusion injury in skeletal muscle. Fundam Clin Pharmacol 2010;24:215–22. doi: 10.1111/j.1472-8206.2009.00748.xErgünYDarendeliSImrekSKilinçMÖksüzH. The comparison of the effects of anesthetic doses of ketamine, propofol, and etomidate on ischemia-reperfusion injury in skeletal muscle. Fundam Clin Pharmacol2010;24:215–22. doi: 10.1111/j.1472-8206.2009.00748.xOpen DOISearch in Google Scholar
Kamiloglu NN, Kamiloglu A, Beytut E. Changes in antioxidant system, lipid peroxidation, heart and respiratory rate and rectal temperature with ketamine and ketamine-xylazine anaestesia in tuj rams. Kafkas Univ Vet Fak Derg 2009;15:205–10. doi: 10.9775/kvfd.2008.101-aKamilogluNNKamilogluABeytutE. Changes in antioxidant system, lipid peroxidation, heart and respiratory rate and rectal temperature with ketamine and ketamine-xylazine anaestesia in tuj rams. Kafkas Univ Vet Fak Derg2009;15:205–10. doi: 10.9775/kvfd.2008.101-aOpen DOISearch in Google Scholar
Traverso N, Ricciarelli R, Nitti M, Marengo B, Furfaro AL, Pronzato MA, Marinari UM, Domenicotti C. Role of glutathione in cancer progression and chemoresistance. Oxid Med Cell Longev 2013;2013:972913. doi: 10.1155/2013/972913TraversoNRicciarelliRNittiMMarengoBFurfaroALPronzatoMAMarinariUMDomenicottiC. Role of glutathione in cancer progression and chemoresistance. Oxid Med Cell Longev2013;2013:972913. doi: 10.1155/2013/972913Open DOISearch in Google Scholar
Ighodaro OM, Akinloye OA. First line defence antioxidants-superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX): their fundamental role in the entire antioxidant defence grid. Alexandria J Med 2018;54:287–93. doi: 10.1016/j.ajme.2017.09.001IghodaroOMAkinloyeOA. First line defence antioxidants-superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX): their fundamental role in the entire antioxidant defence grid. Alexandria J Med2018;54:287–93. doi: 10.1016/j.ajme.2017.09.001Open DOISearch in Google Scholar
Oberley TO, Oberley W. Histology and histopathology from cell biology to tissue engineering antioxidant enzyme levels in cancer. Histol Histopathol 1997;12:525–35. PMID: 9151141OberleyTOOberleyW. Histology and histopathology from cell biology to tissue engineering antioxidant enzyme levels in cancer. Histol Histopathol1997;12:525–35. PMID: 9151141Search in Google Scholar
Tsang CK, Liu Y, Thomas J, Zhang Y, Zheng XFS. Superoxide dismutase 1 acts as a nuclear transcription factor to regulate oxidative stress resistance. Nat Commun 2014;5:3446. doi: 10.1038/ncomms4446TsangCKLiuYThomasJZhangYZhengXFS. Superoxide dismutase 1 acts as a nuclear transcription factor to regulate oxidative stress resistance. Nat Commun2014;5:3446. doi: 10.1038/ncomms4446Open DOISearch in Google Scholar
Braun S, Werdehausen R, Gaza N, Hermanns H, Kremer D, Küry P, Hollmann MW, Stevens MF. Benzethonium increases the cytotoxicity of S(+)-ketamine in lymphoma, neuronal, and glial cells. Anesth Analg 2010;111:1389–93. doi: 10.1213/ANE.0b013e3181f690e4BraunSWerdehausenRGazaNHermannsHKremerDKüryPHollmannMWStevensMF. Benzethonium increases the cytotoxicity of S(+)-ketamine in lymphoma, neuronal, and glial cells. Anesth Analg2010;111:1389–93. doi: 10.1213/ANE.0b013e3181f690e4Open DOISearch in Google Scholar
Lee ST, Wu TT, Yu PY, Chen RM. Apoptotic insults to human HepG2 cells induced by S-(+)-ketamine occurs through activation of a Bax-mitochondria-caspase protease pathway. Br J Anaesth 2009;102:80–9. doi: 10.1093/bja/aen322LeeSTWuTTYuPYChenRM. Apoptotic insults to human HepG2 cells induced by S-(+)-ketamine occurs through activation of a Bax-mitochondria-caspase protease pathway. Br J Anaesth2009;102:80–9. doi: 10.1093/bja/aen322Open DOISearch in Google Scholar
Chen Y, Yang Z, Wei L, Wang J, Xuan W, Wang Y, Li J, Ke Z, Li Y. Yes-associated protein protects and rescues SH-SY5Y cells from ketamine-induced apoptosis. Mol Med Rep 2020;22:2342–50. doi: 10.3892/mmr.2020.11328ChenYYangZWeiLWangJXuanWWangYLiJKeZLiY. Yes-associated protein protects and rescues SH-SY5Y cells from ketamine-induced apoptosis. Mol Med Rep2020;22:2342–50. doi: 10.3892/mmr.2020.11328Open DOISearch in Google Scholar
Zhang Y, Ye F, Zhang T, Lv S, Zhou L, Du D, Lin H, Guo F, Luo C, Zhu S. Structural basis of ketamine action on human NMDA receptors. Nature 2021;598(7882):E3. doi: 10.1038/s41586-021-04038-5ZhangYYeFZhangTLvSZhouLDuDLinHGuoFLuoCZhuS. Structural basis of ketamine action on human NMDA receptors. Nature2021;598(7882):E3. doi: 10.1038/s41586-021-04038-5Open DOISearch in Google Scholar
