Acceso abierto

Clara cell protein 16 release from the nasal mucosa in allergic rhinitis, chronic rhinosinusitis, and exposure to air pollutants


1. Galli SJ, Tsai M, Piliponsky AM. The development of allergic inflammation. Nature 2008;454:445-54. doi: 10.1038/nature07204Search in Google Scholar

2. Oğhan F, Erdin I. Association among high altitude, allergic rhinitis, and bronchial hyperreactivity. ENT Updates 2017;7:47-52. doi: 10.2399/jmu.2017001006Search in Google Scholar

3. Perić A, Vojvodić D, Vukomanović-Đurđević B, Baletić N. Eosinophilic inflammation in allergic rhinitis and nasal polyposis. Arh Hig Rada Toksikol 2011;62:341-8. doi: 10.2478/10004-1254-62-2011-2120Search in Google Scholar

4. Henriquez OA, Beste KD, Hoddeson EK, Parkos CA, Nusrat A, Wise SK. House dust mite Der p 1 effects on sininasal epithelial tight junction. Int Forum Allergy Rhinol 2013;3:630-5. doi: 10.1002/alr.21168Search in Google Scholar

5. Wise SK, Laury AM, Katz EH, Den Beste KA, Parkos CA, Nusrat A. IL-4 and IL-13 compromise the sinonasal epithelial abrrier and perturb intercellular junction protein expression. Int Forum Allergy Rhinol 2014;4:361-70.10.1002/alr.21298415885324510479Search in Google Scholar

6. De Corso E, Baroni S, Romitelli F, Luca L, Di Nardo W, Passali GC, Paludetti G. Nasal lavage CCL24 levels correlate with eosinophil trafficking and symptoms in chronic sinonasal eosinophilic inflammation. Rhinology 2011;49:174-9. doi: 10.4193/Rhino10.133Search in Google Scholar

7. Perić A, Sotirović J, Špadijer-Mirković C, Matković-Jožin S, Perić AV, Vojvodić D. Nonselective chemokine levels in nasal secretions of patients with perennial non-allergic and allergic rhinitis. Int Forum Allergy Rhinol 2016;6:392-7. doi: 10.1002/alr.21684Search in Google Scholar

8. Perić A, Baletić N, Sotirović J, Špadijer-Mirković C. Macrophage inflammatory protein-1 production and eosinophil infiltration in chronic rhinosinusitis with nasal polyps. Ann Otol Rhinol Laryngol 2015;124:266-72. doi: 10.1177/0003489414554944Search in Google Scholar

9. Johansson S, Keen C, Ståhl A, Wennergren G, Benson M. Low levels of CC16 in nasal fluid of children with birch pollen-induced rhinitis. Allergy 2005;60:638-42. doi: 10.1111/j.1398-9995.2005.00775.xSearch in Google Scholar

10. Benson M, Jansson L, Adner M, Luts A, Uddman R, Cardell LO. Gene profiling reveals decreased expression of uteroglobin and other anti-inflammatory genes in nasal fluid cells from patients with intermittent allergic rhinitis. Clin Exp Allergy 2005;35:473-8. doi: 10.1111/j.1365-2222.2005.02206.xSearch in Google Scholar

11. Benson M, Fransson M, Martinsson T, Naluai AT, Uddman R, Cardell LO. Inverse relation between nasal Clara Cell Protein 16 levels and symptoms and signs of rhinitis in allergen-challenged patients with intermittent allergic rhinitis. Allergy 2007;62:178-83. doi: 10.1111/j.1398-9995. 2006.01264.xSearch in Google Scholar

12. Irander K, Palm JP, Borres MP, Ghafouri B. Clara cell protein in nasal lavage fluid and nasal nitric oxide - biomarkers with anti-inflammatory properties in allergic rhinitis. Clin Mol Allergy 2012;10:4. doi: 10.1186/1476-7961-10-4Search in Google Scholar

13. Roth FD, Quintar AA, Leimgruber C, Garcia L, Uribe Echevarria EM, Torres AI. Restoration of the normal Clara cell phenotype after chronic allergic inflammation. Int J Exp Pathol 2013;94:399-411. doi: 10.1111/iep.12041Search in Google Scholar

14. Špadijer-Mirković C, Perić A, Belić B, Vojvodić D. Clara cell protein 16 and eosinophil cationic protein production in chronically inflamed sinonasal mucosa. Int Forum Allergy Rhinol 2016;6:529-35. doi: 10.1002/alr.21710Search in Google Scholar

15. Špadijer-Mirković C. Značaj određivanja medijatora inflamacije u nosnom sekretu za procenu intenziteta zapaljenja u alergijskom rinitisu [Importance of determination of inflammatory mediators in nasal secretions for estimation of the inflammation intensity in allergic rhinitis, in Serbian]. [PhD thesis]. Kragujevac: Faculty of Medical Sciences; 2016.Search in Google Scholar

16. Liu Z, Lu X, Zhang X.H, Bochner BS, Long XB, Zhang F, Wang H, Cui YH. Clara cell 10-kDa protein expression in chronic rhinosinusitis and its cytokine-driven regulation in sinonasal mucosa. Allergy 2009;64:149-57. doi: 10.1111/j.1398-9995.2008.01847.xSearch in Google Scholar

17. Otto BA, Wenzel SE. The role of cytokines in chronic rhinosinusitis with nasal polyps. Curr Opin Otolaryngol Head Neck Surg 2008;16:270-4.doi:10.1097/MOO.0b013e3282fb2885Search in Google Scholar

18. Hemelaers L, Henket M, Sele J, Burreau F, Louis R. Cysteinyl-leukotrienes contribute to sputum eosinophil chemotactic activity in asthmatics. Allergy 2006;61:136-9. doi: 10.1111/j.1398-9995.2006.00993.xSearch in Google Scholar

19. Kramer MF, Burow G, Pfrogner E, Rasp G. In vitro diagnosis of chronic nasal inflammation. Clin Exp Allergy 2004;34:1086-92. doi: 10.1111/j.1365-2222.2004.01989.xSearch in Google Scholar

20. Shin SH, Lee SH, Jeong HS, Kita H. The effect of nasal polyp epithelial cells on eosinophil activation. Laryngoscope 2003;113:1374-7. doi: 10.1097/00005537-200308000-00020Search in Google Scholar

21. Perić A, Špadijer-Mirković C, Vukomanović-Đurđević B, Perić AV, Vojvodić D. Eosinophil chemokines and Clara cell protein 16 production in nasal mucosa of patients with persistent allergic rhinitis. Eurasian J Med 2017;49:178-82. doi: 10.5152/eurasianjmed.2017.17203Search in Google Scholar

22. Shin SH, Park JY, Jeon CH, Choi JK, Lee SH. Quantitative analysis of eotaxin and RANTES messenger RNA in nasal polyps: association of tissue and nasal eosinophils. Laryngoscope 2000;110:1353-7. doi: 10.1097/00005537-200008000-00025Search in Google Scholar

23. Hung CH, Chen LC, Zhang Z, Chowdhury B, Lee WL, Plunkett B, Chen CH, Myers AC, Huang SK. Regulation of Th2 responses by the pulmonary Clara cell secretory 10-kd protein. J Allergy Clin Immun 2004;114:664-70. doi: 10.1016/j.jaci.2004.05.042Search in Google Scholar

24. Mener DJ, Shargorodsky J, Varadhan R, Li SY. Topical intranasal corticosteroids and growth velocity in children: a meta-analysis. Int Forum Allergy Rhinol 2015;5:95-103. doi: 10.1002/alr.21430Search in Google Scholar

25. Bernard AM, Roels HA, Buchet JP, Lauwerys RR. Serum clara cell protein: an indicator of bronchial cell dysfunction caused by tobacco smoking. Environ Res 1994;66:96-104. doi: 10.1006/enrs.1994.1047Search in Google Scholar

26. Van Miert E, Sardella A, Nickmilder M, Bernard A. Respiratory effects associated with wood fuel use: a cross sectional biomarker study among adolescents. Pediatr Pulmonol 2012;47:358-66. doi: 10.1002/ppul.21554Search in Google Scholar

27. Berthoin K, Broeckaert F, Robin M, Haufroid V, De Burbure C, Bernard A. Serum pneumoproteins and biomarkers of exposure to urban air pollution: a cross-sectional comparison of policeman and foresters. Biomarkers 2004;9:341-52. doi: 10.1080/13547500400018646Search in Google Scholar

28. Biagioni BJ, Tam S, Chen YWR, Sin DD, Carlsten C. Effect of controlled human exposure to diesel exhaust and allergen on airway surfactant protein D, myeloperoxidase and club (Clara) cell secretory protein 16. Clin Exp Allergy 2016;46:1206-13. doi: 10.1111/cea.12732Search in Google Scholar

29. Xiao C, Li S, Zhou W, Shang D, Zhao S, Zhu X, Chen K, Wang R. The effect of air pollutants on the microecology of the respiratory tract of rats. Environ Toxicol Pharmacol 2013;36:588-94. doi: 10.1016/j.etap.2013.04.012Search in Google Scholar

30. Carbonnelle S, Francaux M, Doyle I, Dumant X, de Barbure C, Morel G, Michel O, Bernard A. Changes in serum pneumoprotein caused by short-term exposures to nitrogen trichloride in indoor chlorinated swimming pools. Biomarkers 2002;7:464-78. doi: 10.1080/13547500210166612.Search in Google Scholar

Inglés, Slovenian
Calendario de la edición:
4 veces al año
Temas de la revista:
Medicine, Basic Medical Science, other