Variable | Total N = 172 | Pre-COVID group N = 86 | COVID group N = 86 | P-value |
---|---|---|---|---|
Duration of symptoms: | 0.603 | |||
No symptoms | 16 (9.3) | 8 (9.3) | 8 (9.3) | |
Up to one month | 11 (6.4) | 4 (4.7) | 7 (8.1) | |
1 to 3 months | 29 (16.9) | 16 (18.6) | 13 (15.1) | |
3 to 6 months | 49 (28.5) | 24 (27.9) | 25 (29.1) | |
6 to 12 months | 13 (7.6) | 4 (4.7) | 9 (10.5) | |
12 and more months | 7 (4.1) | 5 (5.8) | 2 (2.3) | |
No data | 47 (27.3) | 25 (29.1) | 22 (25.6) | |
Smoking: | 0.264 | |||
Yes | 93 (54.1) | 50 (58.1) | 43 (50.0) | |
No | 60 (34.9) | 25 (29.1) | 35 (40.7) | |
No data | 19 (11.0) | 11 (12.8) | 8 (9.3) | |
Type of treatment: | 0.768 | |||
Radical | 118 (68.6) | 62 (72.1) | 56 (65.1) | |
Palliative | 15 (8.7) | 6 (7.0) | 9 (10.5) | |
Induct | 15 (8.7) | 7 (8.1) | 8 (9.3) | |
Other | 24 (14.0) | 11 (12.8) | 13 (15.1) | |
Treatment method: | 0.657 | |||
Surgery | 38 (22.1) | 20 (23.3) | 18 (20.9) | |
RTh | 32 (18.6) | 14 (16.3) | 18 (20.9) | |
Surgery + RTh/RCTh | 33 (19.2) | 17 (19.8) | 16 (18.6) | |
RCTh | 19 (11.0) | 12 (14.0) | 7 (8.1) | |
CTh + surgery | 1 (0.6) | 1 (1.2) | 0 (0.0) | |
CTh | 21 (12.2) | 8 (9.3) | 13 (15.1) | |
Other | 28 (16.3) | 14 (16.3) | 14 (16.3) |
Variable | Total N = 172 | pre-COVID group N = 86 | COVID group N = 86 | P-value |
---|---|---|---|---|
Tumor: | 0.249 | |||
T0, n (%) | 12 (7.0) | 9 (10.5) | 3 (3.5) | |
T1, n (%) | 41 (23.8) | 23 (26.7) | 18 (20.9) | |
T2, n (%) | 28 (16.3) | 13 (15.1) | 15 (17.4) | |
T3, n (%) | 29 (16.9) | 10 (11.6) | 19 (22.1) | |
T4a, n (%) | 47 (27.3) | 24 (27.9) | 23 (26.7) | |
T4b, n (%) | 15 (8.7) | 7 (8.1) | 8 (9.3) | |
Lymph nodes: | 0.693 | |||
N0, n (%) | 77 (44.8) | 40 (46.5) | 37 (43.0) | |
N1, n (%) | 15 (8.7) | 8 (9.3) | 7 (8.2) | |
N2, n (%) | 51 (29.6) | 22 (25.6) | 29 (33.7) | |
N3, n (%) | 29 (16.9) | 16 (18.6) | 13 (15.1) | |
Metastasis: | 0.329 | |||
M0, n (%) | 162 (94.2) | 83 (96.5) | 79 (91.9) | |
M1, n (%) | 10 (5.8) | 3 (3.5) | 7 (8.1) | |
Grading: | 0.429 | |||
G1, n (%) | 22 (12.8) | 13 (15.1) | 9 (10.5) | |
G2, n (%) | 98 (57.0) | 50 (58.1) | 48 (55.8) | |
G3, n (%) | 27 (15.7) | 14 (16.3) | 13 (15.1) | |
No data, n (%) | 25 (14.5) | 9 (10.5) | 16 (18.6) | |
Stage: | 0.758 | |||
I, n (%) | 35 (20.3) | 18 (20.9) | 17 (19.8) | |
II, n (%) | 17 (9.9) | 10 (11.6) | 7 (8.1) | |
III, n (%) | 23 (13.4) | 12 (14.0) | 11 (12.8) | |
IVA, n (%) | 51 (29.7) | 25 (29.1) | 26 (30.2) | |
IVB, n (%) | 38 (22.1) | 19 (22.1) | 19 (22.1) | |
IVC, n (%) | 8 (4.7) | 2 (2.3) | 6 (7.0) | |
Histopathological diagnosis: | 0.541 | |||
Squamous cell carcinoma | 143 (83.1) | 73 (84.9) | 70 (81.4) | |
Others | 29 (16.9) | 13 (15.1) | 16 (18.6) | |
Location: | 0.360 | |||
Lip and Oral Cavity | 7 (4.1) | 5 (5,8) | 2 (2,3) | |
Nasopharynx | 4 (2.3) | 2 (2,3) | 2 (2,3) | |
Hypopharynx | 31 (18.0) | 12 (14,0) | 19 (22,1) | |
Oropharynx | 16 (9.3) | 6 (7,0) | 10 (11,6) | |
Larynx | 80 (46.5) | 41 (47,7) | 39 (45,3) | |
Nasal Cavity and Paranasal Sinuses | 8 (4.7) | 5 (5,8) | 3 (3,5) | |
Unknown Primary | 12 (7.0) | 9 (10,5) | 3 (3,5) | |
Major Salivary Glands | 14 (8.1) | 6 (7,0) | 8 (9,3) |
Dyspnoea | P-value | OR (95% CI) | ||
---|---|---|---|---|
Yes (N = 18) | No (N = 154) | |||
During a pandemic | 11 (61.1) | 75 (48.7) | 0.455 | 1.66 (0.61; 4.49) |
Before the pandemic | 7 (38.9) | 79 (51.3) | 1.00 (ref.) | |
Emergency tracheotomy | ||||
Yes (N = 16) | No (N = 156) | |||
During a pandemic | 10 (62.5) | 76 (48.7) | 0.294 | 1.75 (0.61; 5.06) |
Before the pandemic | 6 (37.5) | 80 (51.3) | 1.00 (ref.) | |
PEG | ||||
Yes (N = 19) | No (N = 153) | |||
During a pandemic | 14 (73.7) | 72 (47.1) | 0.049 | 3.15 (1.08; 9.18) |
Before the pandemic | 5 (26.3) | 81 (52.9) | 1.00 (ref.) |
Variable | Total N = 172 | pre-COVID group N = 86 | COVID group N = 86 | P-value |
---|---|---|---|---|
Gender: | 0.141 | |||
Female, n (%) | 38 (22.1) | 15 (17.4) | 23 (26.7) | |
Male, n (%) | 134 (77.9) | 71 (82.6) | 63 (73.3) | |
Age (years): | 0.703 | |||
M ± SD | 63.8 ± 10.6 | 63.5 ± 10.9 | 64.1 ± 10.3 | |
Me [Q1; Q3] | 63 [59; 71] | 63 [58; 71] | 64 [60; 70] | |
Min - Max | 30 – 86 | 30 – 86 | 34 – 85 | |
BMI (kg/m2): | 0.235 | |||
M ± SD | 25.4 ± 5.1 | 25.9 ± 5.4 | 24.8 ± 4.9 | |
Me [Q1; Q3] | 25 [22; 28] | 26 [22; 30] | 25 [22; 27] | |
Min - Max | 16 – 47 | 16 – 39 | 16 – 47 | |
BMI: | 0.168 | |||
Thinness (Less than 17), n (%) | 4 (2.3) | 2 (2.3) | 2 (2.3) | |
Underweight (17.0 – 18.4), n (%) | 3 (1.7) | 1 (1.2) | 2 (2.3) | |
Normal weight (18.5 – 24.9), n (%) | 48 (27.9) | 24 (27.9) | 24 (27.9) | |
Overweight (25.0 – 29.9), n (%) | 37 (21.5) | 16 (18.6) | 21 (24.4) | |
Obesity (30 and more), n (%) | 19 (11.0) | 15 (17.4) | 4 (4.7) | |
No data, n (%) | 61 (35.5) | 28 (32.6) | 33 (38.4) | |
Distance (km): | 0.203 | |||
M ± SD | 25.4 ± 5.1 | 25.9 ± 5.4 | 24.8 ± 4.9 | |
Me [Q1; Q3] | 25 [22; 28] | 26 [22; 30] | 25 [22; 27] | |
Min - Max | 16 – 47 | 16 – 39 | 16 – 47 | |
Distance: | 0.321 | |||
a) 0 – 9 km | 38 (22.1) | 22 (25.6) | 16 (18.6) | |
b) 10 – 24 km | 18 (10.5) | 8 (9.3) | 10 (11.6) | |
c) 25 – 49 km | 24 (14.0) | 13 (15.1) | 11 (12.8) | |
d) 50 – 74 km | 41 (23.8) | 24 (27.9) | 17 (19.8) | |
e) 75 – 99 km | 32 (18.6) | 12 (14.0) | 20 (23.3) | |
f) 100 – 252 km | 19 (11.0) | 7 (8.1) | 12 (14.0) |