Investigation of the effect of yarrow (Achillea millefolium ) on Ehrlich ascites tumor
Mustafa Nisari
Perfil de Orcid, Neriman İnanç
Perfil de Orcid, Adem Tokpınar
Perfil de Orcid, Özge Al
Perfil de Orcid, Sümeyye Uçar
Perfil de Orcid, Mustafa Taştan
Perfil de Orcid, Şükrü Ateş
Perfil de Orcid y Seher Yılmaz
Perfil de Orcid 
Categoría del artículo: Original Study
Publicado en línea: 20 oct 2022
Páginas: 431 - 443
Recibido: 26 jul 2021
Aceptado: 23 ene 2022
DOI: https://doi.org/10.2478/ahem-2022-0028
Palabras clave
© 2022 Mustafa Nisari et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Introduction
One of the most important health problems today is cancer. The aim of this study was to investigate the in vitro effect of yarrow (Y) with known anticarcinogenic effect on Ehrlich ascites tumor (EAT).
Materials and Methods
The above-ground part (300 g) of Y was macerated with water and extracted three times for 24 hours at 37°C in a shaking water bath. In the study, EAT cells were divided into control, DMSO group 5-FU, 50, 100, 200, 400 and 800 μg/ml YP groups.
Results
At the end of the hour, it was observed that total apoptosis increased significantly in Y groups (especially 50 μg/ml) compared to the control group (
Conclusions
The results obtained showed that Y extract may have an antitumoral effect on EAT cells. It is thought that this study will contribute to studies on cancer treatment.