<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Cell lines are an important tool for scientific research and clinical and pharmaceutical applications. Cells are isolated from animal tissues and can be expanded in culture to study cell biology and disease. The isolated cells can be used to produce antibodies, proteins, and vaccines. Immortalized cell lines can grow in vitro and are commonly used as models for complex biology. The most frequently used type of cell culture for scientific research and clinical and pharmaceutical applications is the two-dimensional (2D) model, but recently, the popularity of the three-dimensional (3D) cultivation method is growing.</p>
</abstract>

Cell lines are an important tool for scientific research and clinical and pharmaceutical applications. Cells are isolated from animal tissues and can be expanded in culture to study cell biology and disease. The isolated cells can be used to produce antibodies, proteins, and vaccines. Immortalized cell lines can grow in vitro and are commonly used as models for complex biology. The most frequently used type of cell culture for scientific research and clinical and pharmaceutical applications is the two-dimensional (2D) model, but recently, the popularity of the three-dimensional (3D) cultivation method is growing.

Spheroids as 3D Cell Models for Testing of Drugs

Faculty of Natural Sciences, Department of Microbiology and Virology

Faculty of Pharmacy, Department of Galenic Pharmacy

Biomedical Research Center of the Slovak Academy of Sciences

European Pharmaceutical Journal

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

{"article-title":"Spheroids as 3D Cell Models for Testing of Drugs"}

Cell lines are an important tool for scientific research and clinical and pharmaceutical applications. Cells are isolated from animal tissues and can be...

Spheroids as 3D Cell Models for Testing of Drugs

Article Category: Special Issue Article

Publicado en línea: 24 ago 2023

Páginas: 37 - 43

Recibido: 22 jun 2023

Aceptado: 23 jun 2023

DOI: https://doi.org/10.2478/afpuc-2023-0008

Palabras clave
2D cell cultures, 3D cell cultures, spheroids, liquid overlay technique

© 2023 E. Nováková et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Spheroids as 3D Cell Models for Testing of Drugs

Article Category: Special Issue Article

Publicado en línea: 24 ago 2023

Páginas: 37 - 43

Recibido: 22 jun 2023

Aceptado: 23 jun 2023

DOI: https://doi.org/10.2478/afpuc-2023-0008

Palabras clave2D cell cultures, 3D cell cultures, spheroids, liquid overlay technique

© 2023 E. Nováková et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Palabras clave
2D cell cultures, 3D cell cultures, spheroids, liquid overlay technique