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Cultural Adaptation and Validation of the EORTC QLQ-BR45 to Assess Health-Related Quality of Life of Breast Cancer Patients


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Figure 1

Flowchart of the developmental sequences of the Egyptian Arabic version of the QLQ-BR45 module.
Flowchart of the developmental sequences of the Egyptian Arabic version of the QLQ-BR45 module.

Socio-demographic data and tumour characteristics of the patients in the study at baseline (n = 74).

Variable Frequency Percentage
Age, years
  <35 8 10.81%
  35–45 26 35.13%
  46–55 21 28.38%
  56–65 19 25.68%
Marital status
  Married 58 78.37%
  Single 5 6.77%
  Widow 11 14.86%
Body mass index
  Normal weight 17 22.97%
  Overweight 26 35.17%
  Obese 31 41.89%
Menopausal state
  Pre-menopause 38 51.35%
  Post-menopause 36 48.65%
Family history of breast cancer
  Yes 15 20.27%
  No 59 79.73%
Comorbidity
  Yes 16 21.62%
  No 58 78.38%
Educational level
  Low level 47 63.51%
  Intermediate level 18 24.32%
  High level 9 12.16%
ECOG performance status
  0 19 25.68%
  1 47 63.51%
  2 8 10.81%
  3 0 0.00%
  4 0 0.00%
Histological type
  IDC 67 90.54%
  ILC/mixed IDC/ILC 7 9.46%
Clinical stage
  IIB 10 13.52%
  IIIA 31 41.89%
  IIIB 33 44.59%
Hormone receptor status
  ER and/or PR positive 63 85.14%
  ER and PR negative 11 14.86%
HER2 status
  Positive 30 40.54%
  Negative 44 59.46%

Reliability of EORTC QLQ-BR45 Arabic version in female breast cancer patients in Egypt (n = 74).

Scale Cronbach’s α valuea
Body image 0.54
Sexual functioning 0.85
Breast satisfaction 0.95
Systemic therapy side effects 0.63
Arm symptoms 0.77
Breast symptoms 0.74
Endocrine therapy symptoms 0.76
Skin mucosis symptoms 0.75
Endocrine sexual symptoms 0.88
Future perspectiveSexual enjoymentUpset by hair loss Single itemSingle itemSingle item

Multi-trait scaling analysis for convergent and divergent validity of EORTC-QLQ-BR45 Arabic version in female breast cancer patients in Egypt (n = 74).

Scale Subscale Item–own scale correlationa Item–other scale correlationa Scaling success
Functional scales
Body image 0.487–0.798 0.032–0.638 4/4
Sexual functioning 0.902–0.924 0.001–0.027 2/2
Breast satisfaction 0.977–0.978 −0.041–0.03 2/2
Symptoms scales
Systemic therapy side effectsb 0.308–0.743 0.002–0.507 7/7
Arm symptoms 0.765–0.872 0.022–0.480 3/3
Breast symptoms 0.649–0.827 0.016–0.308 4/4
Target therapy scales
Endocrine therapy symptomsb 0.397–0.879 0.003–0.773 10/10
Skin mucosis symptoms 0.425–0.796 0.055–0.541 6/6
Endocrine sexual symptoms 0.940–0.959 0.004–0.635 4/4
eISSN:
2453-6725
Idioma:
Inglés
Calendario de la edición:
2 veces al año
Temas de la revista:
Pharmacy, other