<abstract xmlns="http://www.w3.org/1999/xhtml"><p>The present paper reports the case of a 3 years old, female Bearded Dragon (<italic>Pogona vitticeps</italic>) presenting lethargy, anorexia, weight loss, and anemia and marked leukocytosis at CBC. The majority of leukocytes were lymphocytic/lymphoblastic cells (97%). Immunocytochemical staining of blood smears marked for CD3 (neg) and CD79a (pos) suggested immunophenotype B. The patient died after one month from diagnosis. Histology evidenced lymphoid infiltration in the heart, spleen, liver, kidneys and gut. In addition, in the bone marrow a massive infiltration of lymphoid cells confirmed the diagnosis of leukemia. Immunohistochemistry confirmed the CD79a positivity of a large part of infiltrating lymphoid cells indicating a B cells immunophenotype of the neoplastic population. The presence of lymphocytosis and multiorgan infiltration supported the diagnosis of lymphocytic leukemia. Finally, a revision of the literature has also been made.</p></abstract>

The present paper reports the case of a 3 years old, female Bearded Dragon (Pogona vitticeps) presenting lethargy, anorexia, weight loss, and anemia and marked leukocytosis at CBC. The majority of leukocytes were lymphocytic/lymphoblastic cells (97%). Immunocytochemical staining of blood smears marked for CD3 (neg) and CD79a (pos) suggested immunophenotype B. The patient died after one month from diagnosis. Histology evidenced lymphoid infiltration in the heart, spleen, liver, kidneys and gut. In addition, in the bone marrow a massive infiltration of lymphoid cells confirmed the diagnosis of leukemia. Immunohistochemistry confirmed the CD79a positivity of a large part of infiltrating lymphoid cells indicating a B cells immunophenotype of the neoplastic population. The presence of lymphocytosis and multiorgan infiltration supported the diagnosis of lymphocytic leukemia. Finally, a revision of the literature has also been made.

A Case of Lymphocytic Leukemia in a Bearded Dragon (<italic>Pogona vitticeps</italic>) and a Review of Literature

Acta Veterinaria

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

A Case of Lymphocytic Leukemia in a Bearded Dragon () and a Review of Literature

The present paper reports the case of a 3 years old, female Bearded Dragon (Pogona vitticeps) presenting lethargy, anorexia, weight loss, and anemia and marked...

A Case of Lymphocytic Leukemia in a Bearded Dragon (Pogona vitticeps) and a Review of Literature

Publicado en línea: 24 sept 2019

Páginas: 360 - 368

Recibido: 24 may 2019

Aceptado: 22 ago 2019

DOI: https://doi.org/10.2478/acve-2019-0030

Palabras clave
Bearded dragon, leukemia, lymphocytosis, review

© 2019 Gavazza Alessandra et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

A Case of Lymphocytic Leukemia in a Bearded Dragon (Pogona vitticeps) and a Review of Literature

Publicado en línea: 24 sept 2019

Páginas: 360 - 368

Recibido: 24 may 2019

Aceptado: 22 ago 2019

DOI: https://doi.org/10.2478/acve-2019-0030

Palabras claveBearded dragon, leukemia, lymphocytosis, review

© 2019 Gavazza Alessandra et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Palabras clave
Bearded dragon, leukemia, lymphocytosis, review