<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Human activities such as deforestation, urbanization, and environmental pollution lead to a reduction in the spatial boundary between wild animals, domestic animals and humans. These activities increase the risk for the emergence of pathogens from the sylvatic cycle in the population of domestic animals and humans. Foxes are recognized as potential reservoirs for a number of bacterial pathogens of medical and public health concern. The aim of the present study was to investigate the prevalence and spatial distribution of bacterial tick-borne pathogens from the Anaplasmataceae family, <italic>Borrelia burgdorferi</italic> sensu lato (s.l.), <italic>Rickettsia</italic> spp., <italic>Coxiella burnetii</italic>, <italic>Francisella tularensis</italic>, <italic>Bartonella</italic> spp., in the red fox population from Serbia and to discuss the obtained results from the epidemiological point of view. Legally hunted red foxes (<italic>Vulpes vulpes</italic>) from 14 localities in Serbia were included in the study and spleen samples from 129 animals were tested with conventional PCR assays for the presence of bacterial tick-borne pathogens. DNA of <italic>Candidatus</italic> Neoehrlichia sp. (FU98), <italic>Borrelia burgdorferi</italic> sensu stricto, <italic>Borrelia lusitaniae,</italic> and <italic>Borrelia garinii</italic> was detected in 6 (4.7%), 1 (0.8%), 2 (1.6%) and 1 (0.8%) animals, respectively. Co-infection by <italic>Candidatus</italic> Neoehrlichia sp. (FU98) and <italic>B. garinii</italic> was detected in one animal. All samples were negative for other tested bacterial tick-borne pathogens. The results of the present study indicate the potential role of foxes in natural cycles of <italic>Candidatus</italic> Neoehrlichia sp. (FU98) and causative agents of Lyme borreliosis in the investigated areas. Further research is required to elucidate the role of foxes in the epidemiology of these and other tick-borne zoonotic pathogens in the Republic of Serbia.</p></abstract>

Human activities such as deforestation, urbanization, and environmental pollution lead to a reduction in the spatial boundary between wild animals, domestic animals and humans. These activities increase the risk for the emergence of pathogens from the sylvatic cycle in the population of domestic animals and humans. Foxes are recognized as potential reservoirs for a number of bacterial pathogens of medical and public health concern. The aim of the present study was to investigate the prevalence and spatial distribution of bacterial tick-borne pathogens from the Anaplasmataceae family, Borrelia burgdorferi sensu lato (s.l.), Rickettsia spp., Coxiella burnetii, Francisella tularensis, Bartonella spp., in the red fox population from Serbia and to discuss the obtained results from the epidemiological point of view. Legally hunted red foxes (Vulpes vulpes) from 14 localities in Serbia were included in the study and spleen samples from 129 animals were tested with conventional PCR assays for the presence of bacterial tick-borne pathogens. DNA of Candidatus Neoehrlichia sp. (FU98), Borrelia burgdorferi sensu stricto, Borrelia lusitaniae, and Borrelia garinii was detected in 6 (4.7%), 1 (0.8%), 2 (1.6%) and 1 (0.8%) animals, respectively. Co-infection by Candidatus Neoehrlichia sp. (FU98) and B. garinii was detected in one animal. All samples were negative for other tested bacterial tick-borne pathogens. The results of the present study indicate the potential role of foxes in natural cycles of Candidatus Neoehrlichia sp. (FU98) and causative agents of Lyme borreliosis in the investigated areas. Further research is required to elucidate the role of foxes in the epidemiology of these and other tick-borne zoonotic pathogens in the Republic of Serbia.

<italic>Candidatus</italic> Neoehrlichia sp. (FU98) and <italic>Borrelia burgdorferi</italic> Sensu Lato in Red Foxes (<italic>Vulpes vulpes</italic>) from Serbia

Group for Medical Entomology, Center of Excellence for Food and Vector-borne Zoonoses, Institute for Medical Research

Department of Infectious Animals Diseases and Diseases of Bees, Faculty of Veterinary Medicine

Institute of Parasitology, Department of Pathobiology

Acta Veterinaria

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

 Neoehrlichia sp. (FU98) and  Sensu Lato in Red Foxes () from Serbia

Human activities such as deforestation, urbanization, and environmental pollution lead to a reduction in the spatial boundary between wild animals, domestic...

Candidatus Neoehrlichia sp. (FU98) and Borrelia burgdorferi Sensu Lato in Red Foxes (Vulpes vulpes) from Serbia

Publicado en línea: 24 sept 2019

Páginas: 312 - 324

Recibido: 18 abr 2019

Aceptado: 23 ago 2019

DOI: https://doi.org/10.2478/acve-2019-0026

Palabras clave
Anaplasmataceae, spp., Neoehrlichia sp. (FU98), foxes, PCR, Serbia

© 2019 Ratko Sukara et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Candidatus Neoehrlichia sp. (FU98) and Borrelia burgdorferi Sensu Lato in Red Foxes (Vulpes vulpes) from Serbia

Publicado en línea: 24 sept 2019

Páginas: 312 - 324

Recibido: 18 abr 2019

Aceptado: 23 ago 2019

DOI: https://doi.org/10.2478/acve-2019-0026

Palabras claveAnaplasmataceae, spp., Neoehrlichia sp. (FU98), foxes, PCR, Serbia

© 2019 Ratko Sukara et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Palabras clave
Anaplasmataceae, spp., Neoehrlichia sp. (FU98), foxes, PCR, Serbia