Complete blood count parameters and inflammation-related biomarkers in patients with colorectal carcinoma

1WHO, WHO global survey on the inclusion of cancer care in health-benefit packages 2020–2021; https://iris.who.int/bitstream/handle/10665/375828/9789240088504-eng.pdf?sequence=1Search in Google Scholar

2A. Alsalman, M. A. Al-Mterin, A. Abu-Dayeh, F. Alloush, K. Murshed and E. Elkord, Associations of complete blood count parameters with disease-free survival in right-and left-sided colorectal cancer patients, J. Pers. Med. 12(5) (2022) Article ID 816 (13 pages); https://doi.org/10.3390/jpm12050816Search in Google Scholar

3B. Baran, N. Mert Ozupek, N. Yerli Tetik, E. Acar, O. Bekcioglu and Y. Baskin, Difference between left-sided and right-sided colorectal cancer: A focused review of literature, Gastroenterol. Res. 11(4) (2018) 264–273; https://doi.org/10.14740/gr1062wSearch in Google Scholar

4H. Zhao, L. Wu, G. Yan, Y. Chen, M. Zhou, Y. Wu and Y. Li, Inflammation and tumor progression: Signaling pathways and targeted intervention, Signal Transduct. Target. Ther. . (2021) Article ID 263 (46 pages); https://doi.org/10.1038/s41392-021-00658-5Search in Google Scholar

5I. A. Issa and M. Noureddine, Colorectal cancer screening: An updated review of the available options, World J. Gastroenterol. 23(28) 5086–5096; https://doi.org/10.3748/wjg.v23.i28.5086Search in Google Scholar

6P. S. Virdee, I. R. Marian, A. Mansouri, L. Elhussein, S. Kirtley, T. Holt and J. Birks, The full blood count blood test for colorectal cancer detection: A systematic review, meta-analysis, and critical appraisal, Cancers 12 (2020) Article ID 2348 (37 pages); https://doi.org/10.3390/cancers12092348Search in Google Scholar

7M. S. Mekić, I. Pedišić, H. Šobat, V. V. Boras, I. Kirac, L. Štefančić, M. Šekerija, B. Vrdoljak and D. Vrdoljak, The role of complete blood count parameters in patients with colorectal cancer, Acta Clin. Croat. 57(4) (2018) 624–629; https://doi.org/10.20471/acc.2018.57.04.03Search in Google Scholar

8M. Stojkovic Lalosevic, A. Pavlovic Markovic, S. Stankovic, M. Stojkovic, I. Dimitrijevic, I. Radoman Vujacic, D. Lalic, T. Milovanovic, I. Dumic and Z. Krivokapic, Combined diagnostic efficacy of neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and mean platelet volume (MPV) as biomarkers of systemic inflammation in the diagnosis of colorectal cancer, Dis. Markers (2019) Article ID 6036979 (7 pages); https://doi.org/10.1155/2019/6036979Search in Google Scholar

9T. Yamamoto, K. Kawada and K. Obama, Inflammation-related biomarkers for the prediction of prognosis in colorectal cancer patients, Int. J. Mol. Sci. 22(15) (2021) Article ID 8002 (14 pages); https://doi.org/10.3390/ijms22158002Search in Google Scholar

10W. Jia, L. Yuan, H. Ni, B. Xu and P. Zhao, Prognostic value of platelet-to-lymphocyte ratio, neutro-phil-to-lymphocyte ratio, and lymphocyte-to-white blood cell ratio in colorectal cancer patients who received neoadjuvant chemotherapy, Technol. Cancer Res. Treat. 20 (2021) 1–10; https://doi.org/10.1177/15330338211034291Search in Google Scholar

11A. Braun, H. J. Anders, T. Gudermann and E. Mammadova-Bach, Platelet-cancer interplay: Molecular mechanisms and new therapeutic avenues, Front. Oncol. 11 (2021) Article ID 665534 (27 pages); https://doi.org/10.3389/fonc.2021.665534Search in Google Scholar

12A. Demirović and B. Krušlin, Recommendations for histopathology report of colorectal carcinoma specimens, HAZU 530 (2017) 67–72; https://doi.org/10.21857/ygjwrc642ySearch in Google Scholar

13X. D. Rao, H. Zhang, Z. S. Xu, H. Cheng, W. Shen and X. P. Wang, Poor prognostic role of the pre-treatment platelet counts in colorectal cancer: A meta-analysis. Vol. 97, Medicine (Baltimore) 97(23) (2018) Article ID e10831 (7 pages); https://doi.org/10.1097/MD.0000000000010831Search in Google Scholar

14X. Zhu, Y. Cao, P. Lu, Y. Kang, Z. Lin, T. Hao and Y. Song, Evaluation of platelet indices as diagnostic biomarkers for colorectal cancer, Sci. Rep. .(1) (2018) Article ID 11814 (7 pages); https://doi.org/10.1038/s41598-018-29293-xSearch in Google Scholar

15Y. Y. Wu, X. Zhang, Y. Y. Qin, J. Q. Qin and F. Q. Lin, Mean platelet volume/platelet count ratio in colorectal cancer: A retrospective clinical study, BMC Cancer 19(1) (2019) Article ID 314 (7 pages); https://doi.org/10.1186/s12885-019-5504-9Search in Google Scholar

16Z. Feng, H. Lin, X. Yang, S. Cao, X. Gu, Z. Zhang and W. Deng, Diagnostic value of inflammation-related indicators in distinguishing early colon cancer and adenomatous oolyps, Cancer Control. 30 (2023) 1–10; https://doi.org/10.1177/10732748231180745Search in Google Scholar

17B. G. Ellis and M. R. Thompson, Factors identifying higher risk rectal bleeding in general practice, Br. J. Gen. Pract. 55(521) (2005) 949–955.Search in Google Scholar

18J. Tibble, G. Sigthorsson, R. Foster, R. Sherwood, M. Fagerhol and I. Bjarnason, Faecal calprotectin and faecal occult blood tests in the diagnosis of colorectal carcinoma and adenoma, Gut 49(3) (2001) 402–408; doi.org/10.1136/gut.49.3.402Search in Google Scholar

19W. Zheng, J. Wu, Y. Peng, J. Sun, P. Cheng and Q. Huang, Tumor-associated neutrophils in colorectal cancer development, progression and immunotherapy, Cancers 14(19) (2022) Article ID 4755 (20 pages); https://doi.org/10.3390/cancers14194755Search in Google Scholar

20Z. Fan, Y. Li, Q. Zhao, L. Fan, B. Tan, J. Zuo, K. Hua and Q. Ji, Highly expressed granulocyte colony-stimulating factor (G-CSF) and granulocyte colony-stimulating factor receptor (G-CSFR) in human gastric cancer leads to poor survival, Med. Sci. Monit. 24 (2018) 1701–1711; https://doi.org/10.12659/MSM.909128Search in Google Scholar

21J. Yang, X. Guo, M. Wang, X. Ma, X. Ye and P. Lin, Pre-treatment inflammatory indexes as predictors of survival and cetuximab efficacy in metastatic colorectal cancer patients with wild-type RAS, Sci. Rep.. (1) (2017) Article ID 17166 (9 pages); https://doi.org/10.1038/s41598-017-17130-6Search in Google Scholar

22T. Sunaga, S. Suzuki, M. Kogo, T. Kurihara, S. Kaji, N. Koike, N. Harada, M. Suzuki and Y. Kiuchi, The association between neutropenia and prognosis in stage III colorectal cancer patients receiving adjuvant chemotherapy, Eur. J. Cancer Care 23(3) (2014) 394–400; https://doi.org/10.1111/ecc.12120Search in Google Scholar

23P. H. Cashin, L. Ghanipour, M. Enblad and D. L. Morris, Neutropenia in colorectal cancer treated with oxaliplatin-based hyperthermic intraperitoneal chemotherapy: An observational cohort study, World J. Gastrointest. Oncol. 12(5) (2020) 549–558; https://doi.org/10.4251/wjgo.v12.i5.549Search in Google Scholar

24S. Hamauchi, K. Yamazaki, T. Masuishi, Y. Kito, A. Komori, T. Tsushima, Y. Narita, A. Todaka, M. Ishihara, T. Yokota, T. Tanaka, N. Machida, S. Kadowaki, A. Fukutomi, T. Ura, Y. Onozawa, M. Ando, M. Tajika, K. Muro, H. Yasui, K. Mori and H. Taniguchi, Neutropenia as a predictive factor in meta-static colorectal cancer treated with TAS-102, Clin. Colorectal Cancer 16(1) (2017) 51–57; https://doi.org/10.1016/j.clcc.2016.07.005Search in Google Scholar

25H. Reichman, D. Karo-Atar and A. Munitz, Emerging roles for eosinophils in the tumor microenvironment, Trends Cancer .(11) (2016) 664–675; https://doi.org/doi:10.1016/j.trecan.2016.10.002Search in Google Scholar

26G. Hu, S. Wang, K. Zhong, F. Xu, L. Huang, W. Chen and P. Cheng, Tumor-associated tissue eosinophilia predicts favorable clinical outcome in solid tumors: A meta-analysis, BMC Cancer 20(1) (2020) Article ID 454 (9 pages); https://doi.org/10.1186/s12885-020-06966-3Search in Google Scholar

27G. Varricchi, M. R. Galdiero, S. Loffredo, V. Lucarini, G. Marone, F. Mattei, G. Marone and G. Schiavoni, Eosinophils: The unsung heroes in cancer? Oncoimmunology .(2) (2018) Article ID e1393134 (12 pages); https://doi.org/10.1080/2162402X.2017.1393134Search in Google Scholar

28Y. Rosman, T. Hornik-Lurie, K. Meir-Shafrir, I. Lachover-Roth, A. Cohen-Engler, A. Munitz and R. Confino-Cohen, Changes in peripheral blood eosinophils may predict colorectal cancer – A retrospective study, World Allergy Organization J. 15(10) (2022) Article ID 100696 (8 pages); https://doi.org/doi:10.1016/j.waojou.2022.100696Search in Google Scholar

29J. C. Chan, D. L. Chan, C. I. Diakos, A. Engel, N. Pavlakis, A. Gill and S. J. Clarke, The lymphocyteto-monocyte ratio is a superior predictor of overall survival in comparison to established biomarkers of resectable colorectal cancer, Ann. Surg. 265(3) (2017) 539–546; https://doi.org/10.1097/SLA.0000000000001743.Search in Google Scholar

30Y. Li, H. Jia, W. Yu, Y. Xu, X. Li, Q. Li and S. Cai, Nomograms for predicting prognostic value of inflammatory biomarkers in colorectal cancer patients after radical resection, Int. J. Cancer 139(1) (2016) 220–231; https://doi.org/10.1002/ijc.30071Search in Google Scholar

31Y. Okugawa, Y. Toiyama, A. Yamamoto, T. Shigemori, S. Ide, T. Kitajima, H. Fujikawa, H. Yasuda, J. Hiro, S. Yoshiyama, T. Yokoe, S. Saigusa, K. Tanaka, Y. Shirai, M. Kobayashi, M. Ohi, T. Araki, D. C. McMillan, C. Miki, A. Goel and M. Kusunokit, Lymphocyte-C-reactive protein ratio as promising new marker for predicting surgical and oncological outcomes in colorectal cancer, Ann. Surg. 272(2) (2020) 342–351; https://doi.org/10.1097/SLA.0000000000003239Search in Google Scholar

32S. Suzuki, T. Akiyoshi, K. Oba, F. Otsuka, T. Tominaga, T. Nagasaki, Y. Fukunaga and M. Ueno, Comprehensive comparative analysis of prognostic value of systemic inflammatory biomarkers for patients with stage ii/iii colon cancer, Ann. Surg. Oncol. 27(3) (2020) 844–852; https://doi.org/10.1245/s10434-019-07904-9Search in Google Scholar

33I. D. Kostakis, A. G. Vaiopoulos, Z. Garoufalia, A. G. Papavassiliou, S. Kykalos, G. Kouraklis and G. Tsourouflis, What can preoperative blood tests tell us about colorectal cancer? JBUON 23(1) (2018) 84–95.Search in Google Scholar