Gellan gum and polyvinylpyrrolidone (PVP) as binding agents in extrusion/spheronization pellet formulations

1. S. Muley, T. Nandgude and S. Poddar, Extrusion-spheronization a promising pelletization technique: In-depth review, Asian. J. Pharm. Sci. 11 (2016) 684–699; https://doi.org/10.1016/j.ajps.2016.08.00110.1016/j.ajps.2016.08.001Search in Google Scholar

2. V. R. Sinha, M. K. Agrawal, A. Agarwal, G. Singh and D. Ghai, Extrusion-Spheronization: Process Variables and Characterization, Crit. Rev. Ther. Drug Carrier Syst. 26 (2009) 275–331; https://doi.org/10.1615/CritRevTherDrugCarrierSyst.v26.i3.2010.1615/CritRevTherDrugCarrierSyst.v26.i3.20Search in Google Scholar

3. A. H. Kibbe, Povidone, in Handbook of Pharmaceutical Excipients (Eds. R. C. Rowe, P. J. Sheskey, M. E. Quinn), 6th ed., Pharmaceutical Press, London 2009, pp. 581–585.Search in Google Scholar

4. V. D. Prajapati, G. K. Jani, B. S. Zala and T. A. Khutliwala, An insight into the emerging exopolysaccharide gellan gum as a novel polymer, Carbohydr. Polym. 93 (2013) 670–678; https://doi.org/10.1016/j.carbpol.2013.01.03010.1016/j.carbpol.2013.01.030Search in Google Scholar

5. T. Osmałek, A. Froelich and S. Tasarek, Application of gellan gum in pharmacy and medicine, Int. J. Pharm. 466 (2014) 328–340; https://doi.org/10.1016/j.ijpharm.2014.03.03810.1016/j.ijpharm.2014.03.038Search in Google Scholar

6. M. G. Issa, L. Pessole, A. I. Takahashi, N. A. Filho and H. G. Ferraz, Physicochemical and dissolution profile characterization of pellets containing different binders obtained by the extrusion-spheronization process, Braz. J. Pharm. Sci. 48 (2012) 379–388; https://doi.org/10.1590/S1984-8250201200030000410.1590/S1984-82502012000300004Search in Google Scholar

7. S. Bialleck and H. Rein, Preparation of starch-based pellets by hot-melt extrusion, Eur. J. Pharm. Biopharm. 79 (2011) 440–448; https://doi.org/10.1016/j.ejpb.2011.04.00.Search in Google Scholar

8. F. Podczeck, S. R. Rahman and J. M. Newton, Evaluation of a standardised procedure to assess the shape of pellets using image analysis, Int. J. Pharm. 192 (1999) 123–138; https://doi.org/10.1016/S0378-5173(99)00302-610.1016/S0378-5173(99)00302-6Search in Google Scholar

9. United States Pharmacopoeia 37, NF 32, 37th ed, The United States Pharmacopeial Convention, Inc., Rockville 2013, p. 4911.Search in Google Scholar

10. Y. Zhang, M. Huo, J. Zhou, A. Zou, W. Li, C. Yao and S. Xie, DDSolver: An Add-In Program for Modeling and Comparison of Drug Dissolution Profiles, AAPS J. 12 (2010) 263–271; https://doi.org/10.1208/s12248-010-9185-110.1208/s12248-010-9185-1289545320373062Search in Google Scholar

11. I. T. Jolliffe, Principal Component Analysis, 2nd ed., Springer, New York 2002, pp. 111–115.10.1007/978-1-4757-1904-8_7Search in Google Scholar

12. E. R. Morris, K. Nishinari and M. Rinaudo, Gelation of gellan – A review, Food Hydrocoll. 28 (2012) 373–411; https://doi.org/10.1016/j.foodhyd.2012.01.00410.1016/j.foodhyd.2012.01.004Search in Google Scholar

13. D. Awanthi De Silva, L. A. Poole-Warren, P. J. Martens and M. in het Panhuis, Mechanical characteristics of swollen gellan gum hydrogels, J. Appl. Polym. Sci. 130 (2013) 3374–3383; https://doi.org/10.1002/app.3958310.1002/app.39583Search in Google Scholar

14. V. M. O. Cardoso, B. S. F. Cury, R. C. Evangelista and M. P. D. Gremião, Development and characterization of cross-linked gellan gum and retrograded starch blend hydrogels for drug delivery applications, J. Mech. Behav. Biomed. Mater. 65 (2017) 317–333; https://doi.org/10.1016/j.jmbbm.2016.08.00510.1016/j.jmbbm.2016.08.00527631170Search in Google Scholar

15. C. Maderuelo, A. Zarzuelo and J. M. Lanao, Critical factors in the release of drugs from sustained release hydrophilic matrices, J. Control. Release154 (2011) 2–19; https://doi.org/10.1016/j.jconrel.2011.04.00210.1016/j.jconrel.2011.04.00221497624Search in Google Scholar