[1. H. Y. Peng, J. R. Du, G. Y. Zhang, X. Kuang, Y. X. Liu, Z. M. Qian and C. Y. Wang, Neuroprotective effect of Z-ligustilide against permanent focal ischemic damage in rats, Biol. Pharm. Bull. 30 (2007) 309-312; DOI: JST.JSTAGE/bpb/30.309 [pii].10.1248/bpb.30.309]Search in Google Scholar
[2. J. Sun, B. K. Tan, S. H. Huang, M. Whiteman and Y. Z. Zhu, Effects of natural products on ischemic heart diseases and cardiovascular system, Acta Pharmacol. Sin. 23(2002) 1142-1151.]Search in Google Scholar
[3. J. Y. Zhan, K. Y. Zheng, K. Y. Zhu, C. W. Bi, W. L. Zhang, C. Y. Du, Q. Fu, T. T. Dong, R. C. Choi, K. W. Tsim and D. T. Lau, Chemical and biological assessment of Angelicae Sinensis Radix after processing with wine: an orthogonal array design to reveal the optimized conditions, J. Agric Food Chem. 59 (2011) 6091-6098; DOI: 10.1021/jf200728e.10.1021/jf200728e]Search in Google Scholar
[4. K. Y. Zheng, R. C. Choi, A. W. Cheung, A. J. Guo, C. W. Bi, K. Y. Zhu, Q. Fu, Y. Du, W. L. Zhang, J. Y. Zhan, R. Duan, D. T. Lau, T. T. Dong and K. W. Tsim, Flavonoids from Radix Astragali induce the expression of erythropoietin in cultured cells: a signaling mediated via the accumulation of hypoxia-inducible factor-1alpha, J. Agric. Food Chem. 59 (2011) 1697-1704; DOI: 10.1021/ jf104018u.]Search in Google Scholar
[5. X. M. Wu, Z. M. Qian, L. Zhu, F. Du, W. H. Yung, Q. Gong and Y. Ke, Neuroprotective effect of ligustilide against ischemia-reperfusion injury via up-regulation of erythropoietin and down- -regulation of RTP801, Br. J. Pharmacol. 164 (2011) 332-343; DOI: 10.1111/j.1476-5381.2011. 01337.x.]Search in Google Scholar
[6. X. Kuang, J. R. Du, Y. X. Liu, G. Y. Zhang and H. Y. Peng, Postischemic administration of Z-ligustilide ameliorates cognitive dysfunction and brain damage induced by permanent forebrain ischemia in rats, Pharmacol. Biochem. Behav. 88 (2008) 213-221; DOI: 10.1016/j.pbb.2007. 08.006.]Search in Google Scholar
[7. X. Kuang, J. R. Du, Y. S. Chen, J. Wang and Y. N. Wang, Protective effect of Z-ligustilide against amyloid beta-induced neurotoxicity is associated with decreased pro-inflammatory markers in rat brains, Pharmacol. Biochem. Behav. 92 (2009) 635-641; DOI: 10.1016/j.pbb.2009.03.007.10.1016/j.pbb.2009.03.007]Search in Google Scholar
[8. F. Cui, L. Feng and J. Hu, Factors affecting stability of z-ligustilide in the volatile oil of radix angelicae sinensis and ligusticum chuanxiong and its stability prediction, Drug Dev. Ind. Pharm. 32 (2006) 747-755; DOI: 10.1080/03639040500529101.10.1080/03639040500529101]Search in Google Scholar
[9. S. Pinnamaneni, N. G. Das and S. K. Das, Formulation approaches for orally administered poorly soluble drugs, Pharmazie 57 (2002) 291-300.]Search in Google Scholar
[10. J. Szejtli, Introduction and general overview of cyclodextrin chemistry, Chem. Rev. 98 (1998) 1743-1754; DOI: cr970022c [pii].10.1021/cr970022c]Search in Google Scholar
[11. L. Szente and J. Szejtli, Highly soluble cyclodextrin derivatives: chemistry, properties, and trends in development, Adv. Drug Deliv. Rev. 36 (1999) 17-28; DOI: S0169-409X(98)00092-1 [pii].10.1016/S0169-409X(98)00092-1]Search in Google Scholar
[12. S. Gould and R. C. Scott, 2-Hydroxypropyl-beta-cyclodextrin (HP-beta-CD): a toxicology review, Food Chem. Toxicol. 43 (2005) 1451-1459; DOI: 10.1016/j.fct.2005.03.007.10.1016/j.fct.2005.03.00716018907]Search in Google Scholar
[13. G. E. Granero, M. M. Maitre, C. Garnero and M. R. Longhi, Synthesis, characterization and in vitro release studies of a new acetazolamide-HP-beta-CD-TEA inclusion complex, Eur. J. Med. Chem. 43 (2008) 464-470; DOI: 10.1016/j.ejmech.2007.03.037.10.1016/j.ejmech.2007.03.03717544174]Search in Google Scholar
[14. B. Yang, J. Lin, Y. Chen and Y. Liu, Artemether/hydroxypropyl-beta-cyclodextrin host-guest system: characterization, phase-solubility and inclusion mode, Bioorg. Med. Chem. 17 (2009) 6311-6317; DOI: 10.1016/j.bmc.2009.07.060.10.1016/j.bmc.2009.07.06019665897]Search in Google Scholar
[15. C. Yuan, Z. Y. Jin, X. M. Xu, H. N. Zhuang and W. Y. Shen, Preparation and stability of the inclusion complex of astaxanthin with hydroxypropyl-beta-cyclodextrin, Food Chem. 109 (2008) 264-268; DOI: 10.1016/j.foodchem.2007.07.051.10.1016/j.foodchem.2007.07.05126003346]Search in Google Scholar
[16. Y. Yu, J. R. Du, C. Y. Wang and Z. M. Qian, Protection against hydrogen peroxide-induced injury by Z-ligustilide in PC12 cells, Exp. Brain Res. 184 (2008) 307-312; DOI: 10.1007/s00221-007- -1100-3.]Search in Google Scholar
[17. Q. F. Zhang, Z. T. Jiang, Y. X. Guo and R. Li, Complexation study of brilliant cresyl blue with beta-cyclodextrin and its derivatives by UV-vis and fluorospectrometry, Spectrochim. Acta A Mol. Biomol. Spectrosc. 69 (2008) 65-70; DOI: 10.1016/j.saa.2007.03.009.10.1016/j.saa.2007.03.00917433764]Search in Google Scholar
[18. L. M. Pinto, L. F. Fraceto, M. H. Santana, T. A. Pertinhez, S. O. Junior and de E. Paula, Physico- -chemical characterization of benzocaine-beta-cyclodextrin inclusion complexes, J. Pharm. Biomed. Anal. 39 (2005) 956-963; DOI: 10.1016/j.jpba.2005.06.010.10.1016/j.jpba.2005.06.01016040222]Search in Google Scholar
[19. X. Ge, Z. Huang, S. L. Tian, Y. L. Huang and C. Z. Zeng, Complexation of carbendazim with hydroxypropyl-beta-cyclodextrin to improve solubility and fungicidal activity, Carbohyd. Polym. 89 (2012) 208-212; DOI: 10.1016/j.carbpol.2012.02.072.10.1016/j.carbpol.2012.02.07224750625]Search in Google Scholar
[20. P. Gornas, G. Neunert, K. Baczynski and K. Polewski, Beta-cyclodextrin complexes with chlorogenic and caffeic acids from coffee brew: Spectroscopic, thermodynamic and molecular modelling study, Food Chem. 114 (2009) 190-196; DOI: 10.1016/j.foodchem.2008.09.048.10.1016/j.foodchem.2008.09.048]Search in Google Scholar
[21. D. R. de Araujo, S. S. Tsuneda, C. M. S. Cereda, F. Del G. F. Carvalho, P. S. C. Preté, S. A. Fernandes, F. Yokaichiya, M. K. K. D. Franco, I. Mazzaro, L. F. Fraceto, A.de F. A. Braga and E. de Paula, Development and pharmacological evaluation of ropivacaine-2-hydroxypropyl-beta- -cyclodextrin inclusion complex, Eur. J. Pharm. Sci. 33 (2008) 60-71; DOI: 10.1016/j.ejps.2007. 09.010.]Search in Google Scholar
[22. P. Mura, E. Adragna, A. M. Rabasco, J. R. Moyano, J. I. Perez-Martinez, A. J. Arias and J. M. Gines, Effects of the host cavity size and the preparation method on the physicochemical properties of ibuproxam-cyclodextrin systems, Drug Dev. Ind. Pharm. 25 (1999) 279-287; DOI: 10.1081/ DDC-100102172.10.1081/DDC-100102172]Search in Google Scholar
[23. E. E. M. Eid, A. B. Abdul, F. E. O. Suliman, M. A. Sukari, A. Rasedee and S. S. Fatah, Characterization of the inclusion complex of zerumbone with hydroxypropyl-beta-cyclodextrin, Carbohyd. Polym. 83 (2011) 1707-1714; DOI: 10.1016/j.carbpol.2010.10.033.10.1016/j.carbpol.2010.10.033]Search in Google Scholar
[24. Y. Y. Hwang, D. C. Shin, Y. S. Nam and B. K. Cho, Characterization, stability, and pharmacokinetics of sibutramine/beta-cyclodextrin inclusion complex, J. Ind. Eng. Chem. 18 (2012) 1412-1417; DOI: 10.1016/j.jiec.2012.01.046.10.1016/j.jiec.2012.01.046]Search in Google Scholar
[25. R. Yan, N. L. Ko, S. L. Li, Y. K. Tam and G. Lin, Pharmacokinetics and metabolism of ligustilide, a major bioactive component in Rhizoma Chuanxiong, in the rat, Drug Metab. Dispos. 36 (2008) 400-408; DOI: 10.1124/dmd.107.017707. 10.1124/dmd.107.01770718039808]Search in Google Scholar