<abstract xmlns="http://www.w3.org/1999/xhtml"><p> Resveratrol is a natural organic compound, polyphenol, produced naturally by some plants in response to several harmful factors such as attack by pathogens, UV radiation, or increased oxidative stress. Many experiments suggest that it triggers mechanisms that counteract aging-related effects and plays a role in insulin resistance as well. It also possesses beneficial properties such as anti-cancer, anti-inflammatory, blood-sugar-lowering and cardiovascular effects. It is supposed to exhibit an interesting activity in neuroprotection - mainly through activation of sirtuins and counteraction in forming peptide aggregates. Still research is needed to evaluate exactly how resveratrol protects neurons, and to develop new, potential, therapeutic drugs</p></abstract>

Resveratrol is a natural organic compound, polyphenol, produced naturally by some plants in response to several harmful factors such as attack by pathogens, UV radiation, or increased oxidative stress. Many experiments suggest that it triggers mechanisms that counteract aging-related effects and plays a role in insulin resistance as well. It also possesses beneficial properties such as anti-cancer, anti-inflammatory, blood-sugar-lowering and cardiovascular effects. It is supposed to exhibit an interesting activity in neuroprotection - mainly through activation of sirtuins and counteraction in forming peptide aggregates. Still research is needed to evaluate exactly how resveratrol protects neurons, and to develop new, potential, therapeutic drugs

Antioxidant Properties of Resveratrol and its Protective Effects in Neurodegenerative Diseases

Department of Radiobiology, Faculty of Biology and Environmental Protection, University of Łódz

Medical Journal of Cell Biology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Resveratrol is a natural organic compound, polyphenol, produced naturally by some plants in response to several harmful factors such as attack by pathogens, UV...

Antioxidant Properties of Resveratrol and its Protective Effects in Neurodegenerative Diseases

Publicado en línea: 30 dic 2014

Páginas: 97 - 117

DOI: https://doi.org/10.2478/acb-2014-0006

Palabras clave
resveratrol, neuroprotection, neurodegenerative diseases, sirtuins, protein aggregates

© by Joanna Gerszon

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Antioxidant Properties of Resveratrol and its Protective Effects in Neurodegenerative Diseases

Publicado en línea: 30 dic 2014

Páginas: 97 - 117

DOI: https://doi.org/10.2478/acb-2014-0006

Palabras claveresveratrol, neuroprotection, neurodegenerative diseases, sirtuins, protein aggregates

© by Joanna Gerszon

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Palabras clave
resveratrol, neuroprotection, neurodegenerative diseases, sirtuins, protein aggregates