<abstract xml:lang="en" xmlns="http://www.w3.org/1999/xhtml"><p>T-2 toxin is the most toxic type A trichothecene mycotoxin. It is the secondary metabolite of the Fusarium fungi, and is common in grain and animal feed. Toxic effects have been shown both in experimental animals and in livestock. It has been implicated in several outbreaks of human mycotoxicoses. Toxic effects in poultry include inhibition of protein, DNA, and RNA synthesis, cytotoxicity, immunomodulation, cell lesions in the digestive tract, organs and skin, neural disturbances and low performance in poultry production (decreased weight gain, egg production, and hatchability). Concentrations of T-2 toxin in feed are usually low, and its immunosuppressive effects and secondary infections often make diagnosis difficult. If at the onset of the disease, a change in diet leads to health and performance improvements in animals, this may point to mycotoxin poisoning. Regular control of grain and feed samples is a valuable preventive measure, and it is accurate only if representative samples are tested. This article reviews the incidence and toxic effects of T-2 toxin in poultry.</p></abstract>

T-2 toxin is the most toxic type A trichothecene mycotoxin. It is the secondary metabolite of the Fusarium fungi, and is common in grain and animal feed. Toxic effects have been shown both in experimental animals and in livestock. It has been implicated in several outbreaks of human mycotoxicoses. Toxic effects in poultry include inhibition of protein, DNA, and RNA synthesis, cytotoxicity, immunomodulation, cell lesions in the digestive tract, organs and skin, neural disturbances and low performance in poultry production (decreased weight gain, egg production, and hatchability). Concentrations of T-2 toxin in feed are usually low, and its immunosuppressive effects and secondary infections often make diagnosis difficult. If at the onset of the disease, a change in diet leads to health and performance improvements in animals, this may point to mycotoxin poisoning. Regular control of grain and feed samples is a valuable preventive measure, and it is accurate only if representative samples are tested. This article reviews the incidence and toxic effects of T-2 toxin in poultry.

T-2 Toxin: Incidence and Toxicity in Poultry

Poultry Centre of the Croatian Veterinary Institute, Zagreb, Croatia

Institute for Medical Research and Occupational Health, Zagreb, Croatia

Archives of Industrial Hygiene and Toxicology

{"article-title":"T-2 Toxin: Incidence and Toxicity in Poultry"}

T-2 toxin is the most toxic type A trichothecene mycotoxin. It is the secondary metabolite of the Fusarium fungi, and is common in grain and animal feed. Toxic...

T-2 Toxin: Incidence and Toxicity in Poultry

Publicado en línea: 11 abr 2008

Páginas: 43 - 52

DOI: https://doi.org/10.2478/10004-1254-59-2008-1843

Palabras clave
citotoksičnost, genotoksičnost, trikotecenski mikotoksini, zakonski propisi

This content is open access.

T-2 Toxin: Incidence and Toxicity in Poultry

Publicado en línea: 11 abr 2008

Páginas: 43 - 52

DOI: https://doi.org/10.2478/10004-1254-59-2008-1843

Palabras clavecitotoksičnost, genotoksičnost, trikotecenski mikotoksini, zakonski propisi

This content is open access.

Palabras clave
citotoksičnost, genotoksičnost, trikotecenski mikotoksini, zakonski propisi