<abstract xmlns="http://www.w3.org/1999/xhtml">This update of the H blood group system (Scharberg EA, Olsen C, Bugert P. The H blood group system. Immunohematology 2016;32:112–8) reports 11 new <italic>FUT1</italic> null alleles: 8 causative for the H– phenotype (Bombay phenotype, Oh), 3 in para-Bombay cases, and 5 new <italic>FUT1</italic> alleles causative for a weak H phenotype (para-Bombay, H+w). The H blood group system (International Society of Blood Transfusion system 18) consists of a single antigen (H) defined by a terminal fucose residue found on red blood cells (RBCs) and in secretions. The H antigen is synthesized on the RBC surface by the <italic>FUT1</italic> gene product fucosyltransferase 1. On epithelial cells and in body fluids, the H antigen is synthesized by the <italic>FUT2</italic> gene product fucosyltransferase 2.</abstract>

This update of the H blood group system (Scharberg EA, Olsen C, Bugert P. The H blood group system. Immunohematology 2016;32:112–8) reports 11 new FUT1 null alleles: 8 causative for the H– phenotype (Bombay phenotype, Oh), 3 in para-Bombay cases, and 5 new FUT1 alleles causative for a weak H phenotype (para-Bombay, H+w). The H blood group system (International Society of Blood Transfusion system 18) consists of a single antigen (H) defined by a terminal fucose residue found on red blood cells (RBCs) and in secretions. The H antigen is synthesized on the RBC surface by the FUT1 gene product fucosyltransferase 1. On epithelial cells and in body fluids, the H antigen is synthesized by the FUT2 gene product fucosyltransferase 2.

An update on the H blood group system

Immunohematology

{"article-title":"An update on the H blood group system"}

This update of the H blood group system (Scharberg EA, Olsen C, Bugert P. The H blood group system. Immunohematology 2016;32:112–8) reports 11 new FUT1 null...

An update on the H blood group system

Publicado en línea: 15 feb 2020

Páginas: 67 - 68

DOI: https://doi.org/10.21307/immunohematology-2020-017

© 2019 E.A. Scharberg et al., published by Sciendo