<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Two individuals with the rare Ge:−2,−3,4 phenotype (Gerbich type of Gerbich negative) were identified in a family of Polynesian descent who reside in the Cook Islands. In initial serologic tests, all other family members typed as Ge-positive, and heterozygous individuals could not be identified. Further studies on blood samples from seven members of this Polynesian family by immunoblotting and hemagglutination tests on trypsin-treated red blood cells showed that normal glycophorin C and the prodUR of the Gerbich allele were inherited in an autosomal dominant manner. <bold><italic>Immunohematology</italic></bold> 1992;8:29–32.</p></abstract>

Two individuals with the rare Ge:−2,−3,4 phenotype (Gerbich type of Gerbich negative) were identified in a family of Polynesian descent who reside in the Cook Islands. In initial serologic tests, all other family members typed as Ge-positive, and heterozygous individuals could not be identified. Further studies on blood samples from seven members of this Polynesian family by immunoblotting and hemagglutination tests on trypsin-treated red blood cells showed that normal glycophorin C and the prodUR of the Gerbich allele were inherited in an autosomal dominant manner. Immunohematology 1992;8:29–32.

A Polynesian family showing co-dominant inheritance of normal glycophorin C and the Gerbich variant form of glycophorin C

Immunohematology

Two individuals with the rare Ge:−2,−3,4 phenotype (Gerbich type of Gerbich negative) were identified in a family of Polynesian descent who reside in the Cook...

A Polynesian family showing co-dominant inheritance of normal glycophorin C and the Gerbich variant form of glycophorin C

Publicado en línea: 06 dic 2020

Páginas: 29 - 32

DOI: https://doi.org/10.21307/immunohematology-2019-979

© 1992 M.E. RED, et al., published by Sciendo