Understanding the decay of Proteins: A Study of Time dependent Microwave Response of pM concentration of Insulin in Buffer Solution

[1]Dmitry V. Matyushov and Alexander Y. Morozov, “Electrostatics of the protein-water interface and the dynamical transition in proteins”, PHYSICAL REVIEW E, Vol. 84, pp-011908, 2011. Search in Google Scholar

[2]Kyritsis, A. Panagopoulou, P. Pissis, R. S. i. Serra, J. L. Gómez Ribelles, and N. Shinyashiki, ”Water and Protein Dynamics in Protein-Water Mixtures over Wide Range of Composition”, IEEE Transactions on Dielectrics and Electrical Search in Google Scholar

[3]O.A. Gorobchenko, O.T. Nikolov, S.V. Gatash, “Conformation transitions of blood proteins under influence of physical factors on microwave dielectric method”, Journal of Quantitative Spectroscopy & Radiative Transfer, vol. 102, pp 18–24, 2006. Search in Google Scholar

[4]Nilashis Nandi and Biman Bagchi, “Dielectric Relaxation of Biological Water”, J. Phys. Chem. B,Vol. 101, pp. 10954-10961, 1997. 47452-2, Kluwer Academic Publishers, New York, 2002. Search in Google Scholar

[5]Satosi Iwamoto and Hitoshi Kumagai, “Analysis of the Dielectric Relaxation of a Gelatin Solution”, Biosci. Biochem., Vol. 62 (7), 1381-1387,1998. Search in Google Scholar

[6]“Formulation, Characterization, and Stability of Protein Drugs: Case Histories”, edited by Rodney Pearlman and Y. John Wang, eBook ISBN: 0-306-Insulation, Vol. 19, No. 4, pp-1239-1246, August 2012. Search in Google Scholar

[7]Laogunt A A, Sheppard R J and Grant E H, “Dielectric properties of insulin in solution”, Phys. Med. Biol. 29, 519 (1984). Search in Google Scholar

[8]Wang J, Jian-Wei Mo, Erdem A, “Single-Use Thick-Film Electrochemical Sensor for Insulin” Electroanal. 14, 1365 (2002). Search in Google Scholar

[9]Snider R M, Ciobanu M, Rue A E, and Cliffel D E, “A multiwalled carbon nanotube/dihydropyran composite film electrode for insulin detection in a microphysiometer chamber”, Anal. Chim. Acta 609, 44 (2008). Search in Google Scholar

[10]Salimi A, Noorbakhasha A, Sharifia E, Emnani A, “Highly sensitive sensor for picomolar detection of insulin at physiological pH, using GC electrode modified with guanine and electrodeposited nickel oxide nanoparticles”, Biosens. Bioelectron. 24, 792 (2008). Search in Google Scholar

[11]Shaforost E N, N.Klein, Vitusevich S A, Barannik A A, and Cherpak N T, “High sensitivity microwave characterization of organic molecule solutions of nanoliter volume”, Appl. Phys. Lett. 94, 112901 (2009). Search in Google Scholar

[12]Shaforost E N, Klein N, Vitusevich S A, Offenhäusser A, and Barannik A A, “Nanoliter liquid characterization by open whispering-gallery mode dielectric resonators at millimeter wave frequencies”, J. Appl. Phys. 104, 074111 (2008). Search in Google Scholar

[13]Sheen J, “Amendment of cavity perturbation technique for loss tangent measurement at microwave frequencies”, J. Appl. Phys. 102, 014102 (2007). Search in Google Scholar

[14]Udo Kaatze, “Complex Permittivity of Water as a Function of Frequency and Temperature”, J. Chem. Eng. Data, Vol. 34, pp. 371 -374, 1989. Search in Google Scholar

[15]Tom Moss and Benoît Leblanc, “DNA-Protein Interactions: Principles and Protocols”, 3^rd Edition. Humana Press, 2009DOI: 10.1007/978-1-60327015-1. Search in Google Scholar

[16]Avram Hershko and Gordon M. Tomkins, “Studies on the Degradation of Tyrosine Aminotransferase in Hepatoma Cells in Culture”, The Journal of Biological Chemistry, Vol. 246. No. 3, Issue of February 10, pp. 710-714, 1971. Search in Google Scholar

[17]Rolf D. Fussganger,* C. Ronald Kahn, Jesse Roth, And Pierre De Meyts, “Binding and Degradation of Insulin by Human Peripheral Granulocytes”, The Journal of Biological Chemistry,Vol. 251, No. 9. Issue of May 10,pp.2761~2769,1976. Search in Google Scholar

[18]Inhibition by Bacitracino f Rat Adipocyte Plasma Membrane Degradation of 1251-InsuliIns Associated with an Increase in Plasma Membrane Bound Insulin and a Potentiation of Glucose Oxidation by Adipocytes”, The Journal of Biological Chemistry, Vol. 257, No. 19. Issue of October 10, pp. 11563-11570, 1982. Search in Google Scholar

[19]Basey-Fisher T H, Hanham S M, Andresen H, Maier S A, Stevens M M, Alford N M, and Klein N, “Microwave Debye relaxation analysis of dissolved proteins: Towards free-solution biosensing”, Appl. Phys. Lett. 99, 233703 (2011). Search in Google Scholar