Perforation completion in oil and gas wells is the most important way of completion engineering, the optimization of perforation completion’s designing is influenced by a variety of factors. In order to get the ideal effect of perforation operation, in this paper, a Perforation plan-decision based on Grey Cluster Relation is putted forward. It aims to provide a scientific guidance for the Perforation. The simulation experimental results show that new models are effective, which offer one kind of science decision-making foundation for petroleum Perforation.