Singh et al.26
|
India |
6 |
1,000 ppm F toothpaste twice daily |
Visual DD |
F varnish (22,600 ppm NaF) |
Placebo varnish |
Once at baseline |
16‒25 |
13/14 |
Each tooth from central incisor to first molar |
Visual score DD score |
F varnish did not improve the progression of WSL |
Du et al.27
|
China |
6 |
F toothpaste twice daily |
DD |
F varnish (22,600 ppm NaF Duraphat) |
Saline solution |
6-times (Once every month) |
12‒22 |
47/49 |
All the teeth |
DD score |
Regular F varnish application may be effective in reducing the development of WSL |
He et al.28
|
China |
6 |
F free toothpaste twice daily (control group); F toothpaste twice daily (intervention group) |
Quantitative light-induced fluorescence (QLF) |
F varnish (22,600 ppm NaF Duraphat) |
Placebo varnish |
6-times (Once every month) |
12 ‒25 |
69/72 |
Maxillary anterior teeth |
QLF |
Regular F varnish application may be effective in reducing the development of WSL |
Restrepo et al.29
|
Brazil |
3 |
1,450 ppm F toothpaste twice daily |
Visual (Nyvad criteria) DD |
F varnish (22,600 ppm NaF Duraphat) |
Saline solution |
Twice (Two applications with one-week interval) |
13‒20 |
10/10 |
Anterior teeth and pre-molars |
Visual (Nyvad criteria) score DD score |
F varnish improved the progression of WSL |