Apomorphine and Domperidone Review

Apokyn (package insert) Morristown, NJ: Vernalis Pharmaceuticals Inc 2006 Apokyn (package insert) Morristown, NJ : Vernalis Pharmaceuticals Inc 2006 Search in Google Scholar

Auffret, M., Drapier, S., & Vérin, M. (2018). Pharmacological Insights into the Use of Apomorphine in Parkinson’s Disease: Clinical Relevance. Clinical Drug Investigation, 38(4), 287-312. doi:10.1007/s40261-018-0619-3 Auffret M. Drapier S. Vérin M. ( 2018 ). Pharmacological Insights into the Use of Apomorphine in Parkinson’s Disease: Clinical Relevance . Clinical Drug Investigation , 38 ( 4 ), 287 - 312 . doi: 10.1007/s40261-018-0619-3 Open DOISearch in Google Scholar

Benarroch, E. E. (2014). The clinical approach to autonomic failure in neurological disorders. Nature Reviews Neurology, 10(7), 396-407. doi:10.1038/nrneurol.2014.88 Benarroch E. E. ( 2014 ). The clinical approach to autonomic failure in neurological disorders . Nature Reviews Neurology , 10 ( 7 ), 396 - 407 . doi: 10.1038/nrneurol.2014.88 Open DOISearch in Google Scholar

Bhidayasiri, R., Garcia Ruiz, P. J., & Henriksen, T. (2016). Practical management of adverse events related to apomorphine therapy. Parkinsonism and Related Disorders, 33, S42-S48. doi:10.1016/j.parkreldis.2016.11.017 Bhidayasiri R. Garcia Ruiz P. J. Henriksen T. ( 2016 ). Practical management of adverse events related to apomorphine therapy . Parkinsonism and Related Disorders , 33 , S42 - S48 . doi: 10.1016/j.parkreldis.2016.11.017 Open DOISearch in Google Scholar

Bhidayasiri, R., Sringean, J., Anan, C., Boonpang, K., Thanawattano, C., & Ray Chaudhuri, K. (2016). Quantitative demonstration of the efficacy of night-time apomorphine infusion to treat nocturnal hypokinesia in Parkinson’s disease using wearable sensors. Parkinsonism & Related Disorders, 33 Suppl 1, S36-S41. doi:https://dx.doi.org/10.1016/j.parkreldis.2016.11.016 Bhidayasiri R. Sringean J. Anan C. Boonpang K. Thanawattano C. Ray Chaudhuri K. ( 2016 ). Quantitative demonstration of the efficacy of night-time apomorphine infusion to treat nocturnal hypokinesia in Parkinson’s disease using wearable sensors . Parkinsonism & Related Disorders , 33 Suppl 1 , S36 - S41 . doi: https://dx.doi.org/10.1016/j.parkreldis.2016.11.016 Search in Google Scholar

Borgemeester, R. W. K., Drent, M., & van Laar, T. (2015). Motor and non-motor outcomes of continuous apomorphine infusion in 125 Parkinson’s disease patients. Parkinsonism and Related Disorders, 23, 17-22. doi:10.1016/j.parkreldis.2015.11.013 Borgemeester R. W. K. Drent M. van Laar T. ( 2015 ). Motor and non-motor outcomes of continuous apomorphine infusion in 125 Parkinson’s disease patients . Parkinsonism and Related Disorders , 23 , 17 - 22 . doi: 10.1016/j.parkreldis.2015.11.013 Open DOISearch in Google Scholar

Borgemeester, R. W. K., & van Laar, T. (2017). Continuous subcutaneous apomorphine infusion in Parkinson’s disease patients with cognitive dysfunction: A retrospective long-term follow-up study. Parkinsonism and Related Disorders, 45, 33-38. doi:10.1016/j.parkreldis.2017.09.025 Borgemeester R. W. K. van Laar T. ( 2017 ). Continuous subcutaneous apomorphine infusion in Parkinson’s disease patients with cognitive dysfunction: A retrospective long-term follow-up study . Parkinsonism and Related Disorders , 45 , 33 - 38 . doi: 10.1016/j.parkreldis.2017.09.025 Open DOISearch in Google Scholar

Borovac, J. A. (2016). Side effects of a dopamine agonist therapy for Parkinson’s disease: a mini-review of clinical pharmacology. (89), 37-47. Borovac J. A. ( 2016 ). Side effects of a dopamine agonist therapy for Parkinson’s disease: a mini-review of clinical pharmacology . ( 89 ), 37 - 47 . Search in Google Scholar

Bowron, A. (2004). Practical considerations in the use of apomorphine injectable. Neurology, 62(6), S32-36. Bowron A. ( 2004 ). Practical considerations in the use of apomorphine injectable . Neurology , 62 ( 6 ), S32 - 36 . Search in Google Scholar

Buffery, P. J., & Strother, R. M. (2015). Domperidone safety: a mini-review of the science of QT prolongation and clinical implications of recent global regulatory recommendations. The New Zealand medical journal, 128(1416), 66-74. Buffery P. J. Strother R. M. ( 2015 ). Domperidone safety: a mini-review of the science of QT prolongation and clinical implications of recent global regulatory recommendations . The New Zealand medical journal , 128 ( 1416 ), 66 - 74 . Search in Google Scholar

Australian injectable drugs handbook (7th edition), (2016). Australian injectable drugs handbook ( 7th edition ), ( 2016 ). Search in Google Scholar

Deloitte Access Economics. (2011). Living with Parkinson’s Disease - update (commissioned by Parkinson’s Australia). Retrieved from https://www2.deloitte.com/au/en/pages/economics/articles/living-with-parkinsons-disease.html Deloitte Access Economics . ( 2011 ). Living with Parkinson’s Disease - update (commissioned by Parkinson’s Australia) . Retrieved from https://www2.deloitte.com/au/en/pages/economics/articles/living-with-parkinsons-disease.html Search in Google Scholar

Djamshidian, A., & Poewe, W. (2016). Apomorphine and levodopa in Parkinson’s disease: Two revolutionary drugs from the 1950’s. Parkinsonism and Related Disorders, 33, S9-S12. doi:10.1016/j.parkreldis.2016.12.004 Djamshidian A. Poewe W. ( 2016 ). Apomorphine and levodopa in Parkinson’s disease: Two revolutionary drugs from the 1950’s . Parkinsonism and Related Disorders , 33 , S9 - S12 . doi: 10.1016/j.parkreldis.2016.12.004 Open DOISearch in Google Scholar

EPHPP (2010). Quality assessment tool for quantitative studies. The Effective Public Health Practice Project. http://www.ephpp.ca/PDF/Quality%20Assessment EPHPP ( 2010 ). Quality assessment tool for quantitative studies. The Effective Public Health Practice Project . http://www.ephpp.ca/PDF/Quality%20Assessment Search in Google Scholar

Grandas, F. (2013). Subcutaneous infusions of apomorphine: a reappraisal of its therapeutic efficacy in advanced Parkinson’s disease. 13, 1343-1353. doi:10.1586/14737175.2013.839235 Grandas F. ( 2013 ). Subcutaneous infusions of apomorphine: a reappraisal of its therapeutic efficacy in advanced Parkinson’s disease . 13 , 1343 - 1353 . doi: 10.1586/14737175.2013.839235 Open DOISearch in Google Scholar

Gunzler, S. A. (2009). Apomorphine in the treatment of Parkinson disease and other movement disorders. Expert Opin Pharmacother, 10(6), 1027-1038. doi:10.1517/14656560902828344 Gunzler S. A. ( 2009 ). Apomorphine in the treatment of Parkinson disease and other movement disorders . Expert Opin Pharmacother , 10 ( 6 ), 1027 - 1038 . doi: 10.1517/14656560902828344 Open DOISearch in Google Scholar

Hauser, R. A., Isaacson, S., & Clinch, T. (2014). Randomized, placebo-controlled trial of trimethobenzamide to control nausea and vomiting during initiation and continued treatment with subcutaneous apomorphine injection. Parkinsonism and Related Disorders, 20 (11), 1171-1176. doi:10.1016/j.parkreldis.2014.08.010 Hauser R. A. Isaacson S. Clinch T. ( 2014 ). Randomized, placebo-controlled trial of trimethobenzamide to control nausea and vomiting during initiation and continued treatment with subcutaneous apomorphine injection . Parkinsonism and Related Disorders , 20 ( 11 ), 1171 - 1176 . doi: 10.1016/j.parkreldis.2014.08.010 Open DOISearch in Google Scholar

Henriksen, T. (2014). Clinical insights into use of apomorphine in Parkinson’s disease: tools for clinicians. Neurodegenerative disease management, 4(3), 271-282. doi:10.2217/nmt.14.17 Henriksen T. ( 2014 ). Clinical insights into use of apomorphine in Parkinson’s disease: tools for clinicians . Neurodegenerative disease management , 4 ( 3 ), 271 - 282 . doi: 10.2217/nmt.14.17 Open DOISearch in Google Scholar

Isaacson, S. H. (2016). Efficacy of apomorphine subcutaneous injections in patients with levodopa dose failures and morning akinesia. Movement Disorders, 31(s2), S680-S680. Isaacson S. H. ( 2016 ). Efficacy of apomorphine subcutaneous injections in patients with levodopa dose failures and morning akinesia . Movement Disorders , 31 ( s2 ), S680 - S680 . Search in Google Scholar

Jellinger, K. (2015). Neuropathobiology of non-motor symptoms in Parkinson disease. Journal of Neural Transmission, 122(10), 1429-1440. doi:10.1007/s00702-015-1405-5 Jellinger K. ( 2015 ). Neuropathobiology of non-motor symptoms in Parkinson disease . Journal of Neural Transmission , 122 ( 10 ), 1429 - 1440 . doi: 10.1007/s00702-015-1405-5 Open DOISearch in Google Scholar

Kaminioti, A. N., Nikitas, G. T., Terlis, A. K., Manolis, A. G., Thomaides, T., & Panousopoulou, A. N. (2013). Ventricular bigeminy after subcutaneous administration of apomorphine in a patient with refractory Parkinson’s disease: a case report. Journal of movement disorders, 6(1), 9. doi:10.14802/jmd.13002 Kaminioti A. N. Nikitas G. T. Terlis A. K. Manolis A. G. Thomaides T. Panousopoulou A. N. ( 2013 ). Ventricular bigeminy after subcutaneous administration of apomorphine in a patient with refractory Parkinson’s disease: a case report . Journal of movement disorders , 6 ( 1 ), 9 . doi: 10.14802/jmd.13002 Open DOISearch in Google Scholar

Katzenschlager, R., Poewe, W., Rascol, O., Trenkwalder, C., Deuschl, G., Chaudhuri, K. R., … Lees, A. (2018). Apomorphine subcutaneous infusion in patients with Parkinson’s disease with persistent motor fluctuations (TOLEDO): a multicentre, double-blind, randomised, placebo-controlled trial. Lancet Neurology, 17(9), 749-759. doi:10.1016/S1474-4422(18)30239-4 Katzenschlager R. Poewe W. Rascol O. Trenkwalder C. Deuschl G. Chaudhuri K. R. Lees A. ( 2018 ). Apomorphine subcutaneous infusion in patients with Parkinson’s disease with persistent motor fluctuations (TOLEDO): a multicentre, double-blind, randomised, placebo-controlled trial . Lancet Neurology , 17 ( 9 ), 749 - 759 . doi: 10.1016/S1474-4422(18)30239-4 Open DOISearch in Google Scholar

Lertxundi, U., Domingo-Echaburu, S., Soraluce, A., Garcia, M., Ruiz-Osante, B., & Aguirre, C. (2013). Domperidone in Parkinson’s disease: a perilous arrhythmogenic or the gold standard? Curr Drug Saf, 8(1), 63-68. Lertxundi U. Domingo-Echaburu S. Soraluce A. Garcia M. Ruiz-Osante B. Aguirre C. ( 2013 ). Domperidone in Parkinson’s disease: a perilous arrhythmogenic or the gold standard? Curr Drug Saf , 8 ( 1 ), 63 - 68 . Search in Google Scholar

LeWitt, P. A., Ondo, W. G., Van Lunen, B., & Bottini, P. B. (2009). Open-label study assessment of safety and adverse effects of subcutaneous apomorphine injections in treating “off” episodes in advanced Parkinson disease. Clinical neuropharmacology, 32 (2), 89-93. doi:https://dx.doi.org/10.1097/WNF.0B013E31816D91F9 LeWitt P. A. Ondo W. G. Van Lunen B. Bottini P. B. ( 2009 ). Open-label study assessment of safety and adverse effects of subcutaneous apomorphine injections in treating “off” episodes in advanced Parkinson disease . Clinical neuropharmacology , 32 ( 2 ), 89 - 93 . doi: https://dx.doi.org/10.1097/WNF.0B013E31816D91F9 Search in Google Scholar

Menon, R., & Stacy, M. (2007). Apomorphine in the treatment of Parkinson’s disease. Expert opinion on pharmacotherapy, 8(12), 1941-1950. doi:10.1517/14656566.8.12.1941 Menon R. Stacy M. ( 2007 ). Apomorphine in the treatment of Parkinson’s disease . Expert opinion on pharmacotherapy , 8 ( 12 ), 1941 - 1950 . doi: 10.1517/14656566.8.12.1941 Open DOISearch in Google Scholar

MIMS Australia. (2013). Anamorph. from Health Communication Network MIMS Australia . ( 2013 ). Anamorph. from Health Communication Network Search in Google Scholar

Mundt-Petersen, U., & Odin, P. (2017). Infusional Therapies, Continuous Dopaminergic Stimulation, and Nonmotor Symptoms. International review of neurobiology, 134, 1019-1044. doi:https://dx.doi.org/10.1016/bs.irn.2017.05.036 Mundt-Petersen U. Odin P. ( 2017 ). Infusional Therapies, Continuous Dopaminergic Stimulation, and Nonmotor Symptoms . International review of neurobiology , 134 , 1019 - 1044 . doi: https://dx.doi.org/10.1016/bs.irn.2017.05.036 Search in Google Scholar

NHS TRUST. (2005). Apomorphine in the treatment of Parkinson’s disease. United Kingdom. NHS TRUST . ( 2005 ). Apomorphine in the treatment of Parkinson’s disease . United Kingdom . Search in Google Scholar

Obering, C. D., Chen, J. J., & Swope, D. M. (2006). Update on apomorphine for the rapid treatment of hypomobility (“off”) episodes in Parkinson’s disease. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 26(6), 840-852. doi:10.1592/phco.26.6.840 Obering C. D. Chen J. J. Swope D. M. ( 2006 ). Update on apomorphine for the rapid treatment of hypomobility (“off”) episodes in Parkinson’s disease . Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy , 26 ( 6 ), 840 - 852 . doi: 10.1592/phco.26.6.840 Open DOISearch in Google Scholar

Page MJ, Moher D, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews. BMJ 2021;372:n160. doi: 10.1136/bmj.n160 Page MJ Moher D Bossuyt PM Boutron I Hoffmann TC Mulrow CD PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews . BMJ 2021 ; 372 : n160 . doi: 10.1136/bmj.n160 Open DOISearch in Google Scholar

Renoux, C., Dell’ Aniello, S., Khairy, P., Marras, C., Bugden, S., Turin, T. C., … Ernst, P. (2016). Ventricular tachyarrhythmia and sudden cardiac death with domperidone use in Parkinson’s disease. British Journal of Clinical Pharmacology, 82(2), 461-472. doi:10.1111/bcp.12964 Renoux C. Dell’ Aniello S. Khairy P. Marras C. Bugden S. Turin T. C. Ernst P. ( 2016 ). Ventricular tachyarrhythmia and sudden cardiac death with domperidone use in Parkinson’s disease . British Journal of Clinical Pharmacology , 82 ( 2 ), 461 - 472 . doi: 10.1111/bcp.12964 Open DOISearch in Google Scholar

Sánchez-Ferro, A., Benito-León, J., & Gómez-Esteban, J. C. (2013). The management of orthostatic hypotension in Parkinson’s disease. frontiers in Neurology, 4(64), 1-11. Sánchez-Ferro A. Benito-León J. Gómez-Esteban J. C. ( 2013 ). The management of orthostatic hypotension in Parkinson’s disease . frontiers in Neurology , 4 ( 64 ), 1 - 11 . Search in Google Scholar

Scorza, F. A., Scorza, C. A., & Ferraz, H. B. (2016). Domperidone, Parkinson disease and sudden cardiac death: Mice and men show the way. Clinics, 71(2), 59-61. doi:10.6061/clinics/2016(02)01 Scorza F. A. Scorza C. A. Ferraz H. B. ( 2016 ). Domperidone, Parkinson disease and sudden cardiac death: Mice and men show the way . Clinics , 71 ( 2 ), 59 - 61 . doi: 10.6061/clinics/2016(02)01 Open DOISearch in Google Scholar

Shea BJ, Grimshaw JM, Wells GA, Boers M, Andersson N, Hamel C, Porter AC, Tugwell P, Moher D, Bouter LM. Development of AM-STAR: a measurement tool to assess the methodological quality of systematic reviews. BMC Med Res Methodol. 2007;7(1):1– 7. https://doi.org/10.1186/1471-2288-7-10 Shea BJ Grimshaw JM Wells GA Boers M Andersson N Hamel C Porter AC Tugwell P Moher D Bouter LM . Development of AM-STAR: a measurement tool to assess the methodological quality of systematic reviews . BMC Med Res Methodol. 2007 ; 7 ( 1 ): 1 – 7 . https://doi.org/10.1186/1471-2288-7-10 Search in Google Scholar

Stocchi, F. (2009). Dopamine receptor agonists in the treatment of advanced Parkinson’s disease. Parkinsonism and Related Disorders, 15(4), S54-S57. doi:10.1016/S1353-8020(09)70836-3 Stocchi F. ( 2009 ). Dopamine receptor agonists in the treatment of advanced Parkinson’s disease . Parkinsonism and Related Disorders , 15 ( 4 ), S54 - S57 . doi: 10.1016/S1353-8020(09)70836-3 Open DOISearch in Google Scholar

Tisch, S., & Bolitho, S. (2018). Apomorphine guidelines. Sydney Tisch S. Bolitho S. ( 2018 ). Apomorphine guidelines . Sydney Search in Google Scholar

Ul Haq, I., Lewitt, P. A., & Fernandez, H. H. (2007). Apomorphine therapy in Parkinson’s disease: a review. Expert opinion on pharmacotherapy, 8(16), 2799-2809. Ul Haq I. Lewitt P. A. Fernandez H. H. ( 2007 ). Apomorphine therapy in Parkinson’s disease: a review . Expert opinion on pharmacotherapy , 8 ( 16 ), 2799 - 2809 . Search in Google Scholar

Wood, L. (2010). Clinical Review and Treatment of Select Adverse Effects of Dopamine Receptor Agonists in Parkinson’s Disease. Drugs & Aging, 27(4), 295-310. doi:10.2165/11318330-000000000-00000 Wood L. ( 2010 ). Clinical Review and Treatment of Select Adverse Effects of Dopamine Receptor Agonists in Parkinson’s Disease . Drugs & Aging , 27 ( 4 ), 295 - 310 . doi: 10.2165/11318330-000000000-00000 Open DOISearch in Google Scholar

Zwar, N. A., Bunker, J. M., Reddel, H. K., Dennis, S. M., Middleton, S., van Schayck, O. C. P., … Xuan, W. (2016). Early intervention for chronic obstructive pulmonary disease by practice nurse and GP teams: a cluster randomized trial. Family Practice, 33 (6), 663-670. doi:10.1093/fampra/cmw077 Zwar N. A. Bunker J. M. Reddel H. K. Dennis S. M. Middleton S. van Schayck O. C. P. Xuan W. ( 2016 ). Early intervention for chronic obstructive pulmonary disease by practice nurse and GP teams: a cluster randomized trial . Family Practice , 33 ( 6 ), 663 - 670 . doi: 10.1093/fampra/cmw077 Open DOISearch in Google Scholar