This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Avrahami D., Shai Y.: A new group of antifungal and antimicrobial lipopeptides derived from non-membrane active peptides conjugated to palmitic acid. J. Biol. Chem. 279, 12277–12285 (2004)Search in Google Scholar
Avrahami D., Shai Y.: Bestowing antifungal and antibacterial activities by lipophilic acid conjugation to D,L-amino acidcontaining antimicrobial peptides: A plausible mode of action. Biochemistry-US, 42, 14946–14956 (2003)10.1021/bi035142v14674771Search in Google Scholar
Avrahami D., Shai Y.: Conjugation of a magainin analogue with lipophilic acids controls hydrophobicity, solution assembly and cell selectivity. Biochemistry-US, 41, 2254–2263 (2002)10.1021/bi011549t11841217Search in Google Scholar
Azmi F, Elliot A.G., Marasini N., Ramu S., Ziora Z., Kavanagh A.M., Blaskovich M.A.T., Cooper M.A., Skwarczynski M., Toth I.: Short cationic lipopeptides as effective antibacterial agents: Design, physicochemical properties and biological evaluation. Bioorgan. Med. Chem. 24, 2235–2241 (2016)Search in Google Scholar
Bahar A.A., Ren D.: Antimicrobial Peptides. Pharmaceuticals, 6, 1543–1575 (2013)10.3390/ph6121543387367624287494Search in Google Scholar
Bai Y., Liu S.P., Jiang P., Zhou L., Li J., Tang C., Verma C., Mu Y.G., Beuerman R.W., Pervushin K.: Structure-dependent charge density as a determinant of antimicrobial activity of peptide analogues of defensin. Biochemistry-US, 48, 7229–7239 (2009)10.1021/bi900670d19580334Search in Google Scholar
Bai Y., Liu S.P., Li J.G., Lakshminarayan R., Sarawathi P., Tang C., Ho D.C., Verma C., Beuerman R.W., Pervushin K.: Progressive Structuring of a Branched Antimicrobial Peptide on the Path to the Inner Membrane Target. J. Biol. Chem. 287, 26606–26617 (2012)Search in Google Scholar
Barańska-Rybak W., Pikuła M., Dawgul M., Kamysz W., Trzonkowski P., Roszkiewicz J.: Safety profile of antimicrobial peptides: Camel, Citropin, Protegrin, Temporin A and lipopetide on HaCaT keratinocytes. Acta. Pol. Pharm. 70, 795–801 (2013)Search in Google Scholar
Barchiesi F., Giacometti A., Cirioni O., Arzeni D., Silvestri C., Kamysz W., Abbruzzetti A., Riva A., Kamysz E., Scalise G.: In vitro activity of the synthetic lipopeptide PAL-Lys-Lys-NH(2) alone and in combination with antifungal agents against clinical isolates of Cryptococcus neoformans. Peptides, 28, 1509–1513 (2007)10.1016/j.peptides.2007.07.01017698253Search in Google Scholar
Bhunia A., Mohanram H., Domadia P.N., Torres J., Bhattacharjya S.: Designed beta-Boomerang Antiendotoxic and Antimicrobial peptides. Structures and activities in lipopolysaccharide, J. Biol. Chem. 284, 21991–22004 (2009)Search in Google Scholar
Błażewicz I., Jaśkiewicz M., Piechowicz L., Kamysz W., Nowicki R., Barańska-Rybak W.: Rola peptydów przeciwdrobnoustrojowych w wybranych dermatozach. Przegl. Dermatol. 103, 227–232 (2016)Search in Google Scholar
Catiau L., Traisnel J., Delval-Dubois V., Chihib N.E., Guillochon D., Nedjar-Arroume N.: Minimal antimicrobial peptidic sequence from hemoglobin alpha-chain: KYR. Peptides, 32, 633–638 (2011)10.1016/j.peptides.2010.12.01621262306Search in Google Scholar
Cirioni O., Scalise G. i wsp.: The lipopeptides Pal-Lys-Lys-NH(2) and Pal-Lys-Lys soaking alone and in combination with intraperitoneal vancomycin prevent vascular graft biofilm in a subcutaneous rat pouch model of staphylococcal infection. Peptides, 28, 1299–1303 (2007)10.1016/j.peptides.2007.03.01717537542Search in Google Scholar
Citterio L., Franzyk H., Palarasah Y., Andersen T.E., Mateiu R.V., Gram L.: Improved in vitro evaluation of novel antimicrobials: potential synergy between human plasma and antibacterial peptidomimetics, AMPs and antibiotics against human pathogenic bacteria, Res. Microbiol. 167, 72–82 (2016)10.1016/j.resmic.2015.10.00226499211Search in Google Scholar
Cochrane A.S, Findlay B., Bakhtiary A., Acedo J.Z., Rodriguez-Lopez E.M, Mercier P., Vederas J.C.: Antimicrobial lipopeptide tridecaptin A1 selectivelybinds to Gram-negative lipid II. P. Natl. Acad. Sci. USA, 113, 11561–11566 (2016)10.1073/pnas.1608623113506828927688760Search in Google Scholar
Dawgul M., Barańska-Rybak W., Greber K., Guzik Ł., Nowicki R., Łukasiak J., Kamysz W.: Aktywność przeciwbakteryjna krótkich lipopeptydów wobec klinicznych szczepów Staphylococcus aureus. Alergia Astma Immunologia, 16, 31–36 (2001)Search in Google Scholar
Dawgul M., Barańska-Rybak W., Bielińska S., Nowicki R., Kamysz W.: Wpływ peptydów przeciwdrobnoustrojowych na biofilm Candida. Alergia Astma Immunologia, 15, 220–225 (2010)Search in Google Scholar
Dawgul M., Maciejewska M., Jaskiewicz M., Karafova A., Kamysz W.: Antimicrobial peptides as potential tool to fight bacterial biofilm, Acta. Pol. Pharm. 71, 39–47 (2014)Search in Google Scholar
Eckhard L.H., Houri-Haddad Y., Sol A., Zeharia R., Shai Y., Beyth S., Domb A.J., Bachrach G., Beyth N.: Sustained release of Antibacterial Lipopeptides from Biodegradable Polymers against Pral Pathogens, Plos One, 11, e0162537 (2016)10.1371/journal.pone.0162537501583527606830Search in Google Scholar
Fenyou She, Nimmagadda A., Teng P., Su M., Zuo X.B., Cai J.F.: Helical 1:1 alpha/Sulfono-gamma-AA Heterogeneous Peptides with Antimicrobial Activity, Biomacromolecules, 17, 1854–1859 (2016)Search in Google Scholar
Giuliani A., Rinaldi A.C.: Beyond natural antimicrobial peptides: multimeric peptides and other peptidomimetic approaches. Cell. Mol. Life Sci. 68, 2255–2266 (2011)10.1007/s00018-011-0717-321598022Search in Google Scholar
Goldberg K. Sarig H., Zakoon F., Espand R.F., Espand R.M., Mor A.: Sensitization of Gram-negative bacteria by targeting the membrane potential. Faseb J. 27, 3818–3826 (2013)Search in Google Scholar
Greber K.E., Dawgul M., Kamysz W., Sawicki W.: Cationic Net Charge and Counter Ion Type as Antimicrobial Activity Determinant Factors of Short Lipopeptides. Front. Microbiol. Doi: 10.3389/fmicb.2017.00123 (2017)10.3389/fmicb.2017.00123528535428203232Search in Google Scholar
Greber K.E., Ciura K., Belka M., Kawczak P., Nowakowska J., Baczek T., Sawicki W.: Characterization of antimicrobial and hemolytic properties of short synthetic cationic lipopeptides based on QSAR/QSTR approach, Amino acids, DOI: 10.1007/s00726-017-2530-2 (2017)10.1007/s00726-017-2530-2585217229264738Search in Google Scholar
Horn J.N., Sengillo J.D., Lin D.J., Romo T.D., Grossfield A.: Characterization of a potent antimicrobial lipopeptide via coarse-grained molecular dynamics, BBA.-Biomembranes. 1818, 212–218 (2012)10.1016/j.bbamem.2011.07.025369433821819964Search in Google Scholar
Hu Y.G., Amin M.N., Padhee S., Wang R.S.E., Qiao Q., Bai G., Li Y.Q., Mathew A., Cao C.H., Cai J.F.: Lipidated peptidomimetics with improved antimicrobial activity. ACS. Med. Chem. Lett.3, 683–686 (2012)10.1021/ml3001215402573724900530Search in Google Scholar
Hu Y.G., Li X.L., Sebti S.M., Chen J.D., Cai J.F.: Design and synthesis of AApeptides: a new class of peptide mimics. Bioorg. Med. Chem. Lett. 21, 1469–1471 (2011)Search in Google Scholar
Iyer V.: A review of stapled peptides and small molecules to inhibit protein-protein interactions in cancer. Curr. Med. Chem. 23, 3025–3043 (2016)Search in Google Scholar
The APD: The Antimicrobial Peptide Database, http://aps.unmc. edu/AP/main.php (24.02.2018)Search in Google Scholar
Jammal J., Zakoon F., Kaneti G., Goldberg K., Mor A.: Sentsitization of Gram-negative bacteria to rifampin and OAK combinations. Sci. Rep.-UK, DOI: 10.1038/srep0921610.1038/srep09216436386025782773Search in Google Scholar
Jammal J., Zaknoon F., Kaneti G., Herhkovits A.S., Mor A.: Sensitization of Gram-negative Bacilli to Host Antimicrobial Proteins, JPN. J. Infect. Dis. 215, 1599–1607 (2017)Search in Google Scholar
Janiszewska J. Naturalne peptydy przeciwdrobnoustrojowe w zastosowaniach biomedycznych. Polimery, 59, 699–707 (2014)10.14314/polimery.2014.699Search in Google Scholar
Janiszewska J., Sowinska M., Rajnisz A., Solecka J., Lacka I., Milewski S., Urbanczyk-Lipkowska Z.: Novel dendrimeric lipopeptides with antifungal activity, Bioorg. Med. Chem. Lett. 22, 1388–1393 (2012)Search in Google Scholar
Jansen R.O., Sandberg-Schaal A., Frimodt-Moller N., Nielsen H.M., Franzyk H.: End group modification: Efficient tool for improving activity of antimicrobial peptide analogues towards Gram-positive bacteria, Eur. J. Pharm. Biopharm. 95, 40–46 (2015)10.1016/j.ejpb.2015.01.01325622790Search in Google Scholar
Jaśkiewicz M., Neubauer D., Kamysz W.: Comparative Study on Antistaphylococcal Activity of Lipopeptides in Various Culture Media. Antibiotics, DOI:10.3390/antibiotics6030015 (2017)10.3390/antibiotics6030015561797928767074Search in Google Scholar
Jenner Z.B., Crittenden C.M., Gonzales M., Brodbelt J.S., Bruns K.A.: Hydrocarbon-stapled lipopeptides exhibit selective antimicrobial activity, Biopolymers, 108, e23006 (2017)10.1002/bip.2300628073163Search in Google Scholar
Jerala R.: Synthetic lipopeptides: a novel class of anti-infectives, Expert. Opin. Inv. Drug. 16, 1159–1169 (2007)Search in Google Scholar
Kamysz E., Barchiesi F. i wsp.: In vitro activity of the lipopeptide PAL-Lys-Lys-NH2, alone and in combination with antifungal agents, against clinical isolates of Candida spp. Peptides, 32, 99–103 (2011)10.1016/j.peptides.2010.10.022Search in Google Scholar
Kamysz E., Sikorska E., Dawgul M., Tyszkowski R., Kamysz W.: Influence of dimerization of lipopeptide Laur-Orn-Orn-Cys-NH2 and N-terminal peptide of human lactoferricin on biological activity. Int. J. Pept. Res. Ther. 21, 39–46 (2015)10.1007/s10989-014-9423-ySearch in Google Scholar
Kamysz W.: Projektowanie, synteza i badania peptydów przeciwdrobnoustrojowych. Akademia Medyczna. Gdańsk, 2007Search in Google Scholar
Kaur P., Li Y.Q., Cai F.J., Song L.K.: Selective membrane disruption mechanism of an antibacterial gamma-AApeptide defined by EPR spectroscopy. Biophys. J. 110, 1789–1799 (2016)Search in Google Scholar
Koh J.J., Lin S.M., Beuerman R.W., Liu S.P.: Recent advances in synthetic lipopeptides as anti-microbial agents: design and synthetic approaches, Amino acids, 49, 1653–1677 (2017)Search in Google Scholar
Kozińska A., Sitkiewicz I.:. "Nowe” i "Stare” antybiotyki – mechanizmy działania i strategie poszukiwania leków przeciwbakteryjnych. Kosmos, 66, 109–124 (2017)Search in Google Scholar
Lakshminarayanan R., Beuerman R.W. I wsp.: Branched peptide, B2088, disrupts the supramolecular organization of lipopolysaccharides and sensitizes the Gram-negative bacteria, Sci. Rep.-UK, 6, DOI: 10.1038/srep25905 (2016)10.1038/srep25905Search in Google Scholar
Laverty G., McLaughlin M., Shaw C., Gorman S.P., Gilmore B.F.: Antimicrobial Activity of Short, Synthetic Cationic Lipopeptides, Chem. Biol. Drug. Des. 75, 563–569 (2010)Search in Google Scholar
Li J., Koh J.J, Liu S., Lakshminarayanan R., Verma C.S, Beuerman R.W.: Membrane Active Antimicrobial Peptides: Translating Mechanistic Insights to Design. Front. Neurosci. Doi: 10.3389/fnins.2017.00073 (2017)10.3389/fnins.2017.00073Search in Google Scholar
Li J.G., Liu S.P., Lakshminarayanan R., Bai Y., Pervushin K., Verma C., Beuerman R.W.: Molecular simulations suggest how a branched antimicrobial peptide perturbs a bacterial membrane and enhances permeability, BBA. – Biomembranes, 1828, 1112–1121 (2013)10.1016/j.bbamem.2012.12.015Search in Google Scholar
Lin D.J., Grossfield A.: Thermodynamics of antimicrobial lipopeptide binding to membranes: origins of affinity and selectivity. Biophys. J. 107, 1862–1872 (2014)Search in Google Scholar
Lohan S., Cameotra S.S., Bisht G.S.: Systematic study of non-natural short cationic lipopeptides as novel broad-spectrum antimicrobial agents. Chem. Biol. Drug. Des. 82, 557–566 (2013)Search in Google Scholar
Majerle A., Kidric J. Jerala R.: Enhancement of antibacterial and lipopolysaccharide binding activities of a human lactoferrin peptide fragment by the addition of acyl chain. J. Antimicrob. Chemoth. 51, 1159–1165 (2003)Search in Google Scholar
Mak P., Pohl J., Dubin A., Reed M.S., Bowers S.E., Fallon M.T., Shafer W.M.: The increased bactericidal activity of a fatty acid-modified synthetic antimicrobial peptide of human cathepsin G correlates with its enhanced capacity to interact with model membranes. Int. J. Antimicrob. Ag. 21, 13–19 (2003)10.1016/S0924-8579(02)00245-5Search in Google Scholar
Makovitzky A., Avrahami D., Shai Y.: Ultrashort antibacterial and antifungal lipopeptides. P. Natl. Acad. Sci. USA, 103, 15997–16002 (2006)10.1073/pnas.0606129103163511617038500Search in Google Scholar
Makovitzky A., Baram J. Shai Y.: Antimicrobial lipopolypeptides composed of palmitoyl di- and tricationic peptides: in vitro and in vivo activities, self-assembly to nanostructures and plausible mode of action. Biochemistry-US, 47, 10630–10636 (2008)10.1021/bi801167518783248Search in Google Scholar
Malina A., Shai Y.: Conjugation of fatty acids with different lengths modulates the antibacterial and antifungal activity of cationic biologically inactive peptide, Biochem. J. 390, 695–702 (2005)Search in Google Scholar
Mangoni M.L., Shai Y.: Short native antimicrobial peptides and engineered ultrashort lipopeptides: similarities and differences in cell specificities and modes of action, Cell Mol. Life Sci. 68, 2267–2280 (2011)10.1007/s00018-011-0718-221573781Search in Google Scholar
Migon D., Neubauer D., Kamysz W.: Hydrocarbon Stapled Antimicrobial Peptides. Protein J. DOI: 10.1007/s10930-018-9755-0 (2018)10.1007/s10930-018-9755-0584227329330644Search in Google Scholar
Min K.R., Galvis A., Williams B., Rayala R., Cudic P., Ajdic D.: Antibacterial and Antibiofilm Activities of a Novel Synthetic Cyclic Lipopeptide against Cariogenic Streptococcus mutans UA159. Antimicrob. Agents. Chemother. DOI: 10.1128/AAC.00776-17 (2017)10.1128/AAC.00776-17552765528533236Search in Google Scholar
Mirski T., Gryko R., Bartoszcze M., Bielwaska-Drózd A., Tyszkiewicz W.: Peptydy przeciwdrobnoustrojowe – nowe możliwości zwalczania infekcji u ludzi i zwierząt. Medycyna Wet. 67, 517–521 (2011)Search in Google Scholar
Mishra B., Lushnikova T., Wang G.S.: Small lipopeptides possess anti-biofilm capability comparable to daptomycin and vancomycin. RSC. Adv. 5, 59758–59769 (2015)Search in Google Scholar
Mizerska-Dudka M., Andrejko M., Kondefer-Szerszeń M.. Przeciwirusowe peptydy kationowe człowieka i owadów. Post. Mikrobiol. 50, 209–216 (2011)Search in Google Scholar
Mohanram H., Bhattacharjya S.: ‘Lollipop’-shaped helical structure of a hybrid antimicrobial peptide of temporin B – lipopolysaccharide binding motif and mapping cationic residues in antibacterial activity, BBA. – Gen. Subjects. 1860, 1362–1372 (2016)10.1016/j.bbagen.2016.03.02527015761Search in Google Scholar
Mohanram H., Bhattacharjya S.: beta-Boomerang Antimicrobial and antiendotoxic peptides: lipidation and disulfide bond effects on activity and structure. Pharmaceuticals (Basel, Switzerland),7, 482–501 (2014)10.3390/ph7040482401470424756162Search in Google Scholar
Nasompag S., Dechsiri P., Hongsing N., Phonimdaeng P., Daduang S., Klaynongsruang S., Camesano T.A., Patramanon R.: Effect of acyl chain length on therapeutic activity and mode of action of the C-X-KYR-NH2 antimicrobial lipopeptide. BBA. – Biomembranes, 1848, 2351–2364 (2015)10.1016/j.bbamem.2015.07.00426170198Search in Google Scholar
Nedjar-Arroume N., Dubois-Delval V., Adje E.Y., Traisnel J., Krier F., Mary P., Kouach M., Briand G., Guillochon D.: Bovine hemoglobin: an attractive source of antibacterial peptides. Peptides, 29, 969–977 (2008)10.1016/j.peptides.2008.01.01118342399Search in Google Scholar
Niu Y.H., Cai J.F I wsp.: Lipo-gamma-AApeptides as a new class of potent and broad-spectrum antimicrobial agents. J. Med. Chem. 55, 4003–4009 (2012)Search in Google Scholar
Omardien S., Brul S., Zaat S.A.J.: Antimicrobial Activity of Cationic Antimicrobial Peptides against Gram-Positives: Current Progress Made in Understanding the Mode of Action and the Response of Bacteria. Front. Cell. Dev. Biol. Doi: 10.3389/fcell.2016.00111 (2016)10.3389/fcell.2016.00111506385727790614Search in Google Scholar
Oren Z., Lerman J.C., Gudmundsson G.H., Agerberth B., Shai Y.: Structure and organization of the human antimicrobial peptide LL-37 in phospholipid membranes: relevance to the molecular basis for its non-cell-selective activity. Biochem. J. 341, 501–513 (1999)10.1042/bj3410501Search in Google Scholar
Padhee S., Li Y.Q., Cai J.F.: Activity of lipo-cyclic gamma-AApeptides against biofilms of Staphyloccocus epidermidisand Pseudomonas aeruginosa, Bioorg. Med. Chem. Lett. 25, 2565–2569 (2015)Search in Google Scholar
Papo N., Oren Z., Pag U., Sahl H.G., Shai Y.: The consequence of sequence alternation of an amphipathic alpha-helical antimicrobial peptide and its diastereomers. J. Biol. Chem. 277, 33913–33921 (2002)Search in Google Scholar
Radzishevsky I.S., Rotem S., Bourdetsky D., Navon-Venezia S., Carmeli Y., Mor A.: Impoved antimicrobial peptides based on acyl-lysine oligomers. Nat. Biotechnol. 25, 657–659 (2007)Search in Google Scholar
Sang P., Shi Y., Teng P., Cao A.N., Xu H., Li Q., Cai J.F.: Antimicrobial AApeptides, Curr. Top. Med. Chem. 17, 1266–1279 (2017)Search in Google Scholar
Sarig H. Livne L., Held-Kutnetsov V., Zakoon F., Ivankin A., Gidalevitz D., Mor A.: A miniature mimic of host defense peptides with systematic antibacterial efficacy. Faseb J. 24, 1904–1913 (2010)Search in Google Scholar
Shai Y., Makovitzky A., Avrahami D.: Host defense peptides and lipopeptides: mode of action and potential candidates for the treatment of bacterial and fungal infections. Curr. Protein Pept. Sci. 7, 479–486 (2006)Search in Google Scholar
Sikorska E., Dawgul M., Greber K., Ilowska E., Pogorzelska A., Kamysz W.: Self-assebly and interactions of short antimicrobial lipopeptides with membrane lipids: ITC, FTIR and molecular dynamics studies. BBA.-Biomembranes, 1838, 2625–2634 (2014)10.1016/j.bbamem.2014.06.01624978107Search in Google Scholar
Straus S.K., Hancock R.E.W.: Mode of action of the new antibiotic for Gram-positive pathogens daptomycin: comparison with cationic antimicrobial peptides and lipopeptides. BBA.-Biomembranes, 1758, 1215–1223 (2006)10.1016/j.bbamem.2006.02.00916615993Search in Google Scholar
Teng P., Cai J.F. I wsp.: Small Antimicrobial Agents Based on Acylated Reduced Amide Scaffold, J. Med. Chem. 59, 7877–7887 (2016)Search in Google Scholar
Wang G.: Improved Methods for Classification, Prediction and Design of Antimicrobial Peptides. Method. Mol. Cell Biol. 1268, 43–66 (2015)Search in Google Scholar
Wiesner J., Vilcinskas A.: Antimicrobial peptides: the ancient arm of the human immune system. Virulence, 1, 440–464 (2010)10.4161/viru.1.5.1298321178486Search in Google Scholar
Wódz K., Brzezińska-Błaszczyk E., Katelicydyny – endogenne peptydy przeciwdrobnoustrojowe. Postępy Biochemii, 61, 93–101 (2015)Search in Google Scholar
Zdybicka-Barabas A., Stączek S., Cytryńska M.: Różnorodność peptydów przeciwdrobnoustrojowych bezkręgowców. Kosmos, 66, 563–574 (2017)Search in Google Scholar
Zhang L.J, Gallo R.L.: Antimicrobial peptides. Curr. Biol. 26, 14–19 (2016)Search in Google Scholar
Żyłowska M., Wyszyńska A., Jagusztyn-Krynicka E.K.: Defensysny – peptydy o aktywności przeciwbakteryjnej. Post. Mikrobiol. 50, 223–234 (2011)Search in Google Scholar
