<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Regenerative endodontics can be defined as a group of procedures that use tissue engineering, gene therapy, and stem cell-based approaches to regenerate tissue in tooth cavities. One of the main advantages of dental pulp revitalization compared to traditional endodontic treatments is that, by maintaining living tissue in the tooth cavity, teeth retain their defensive, nutritional, and sensory abilities which can provide protection against potential infection. This review discusses the application of stem cells in dental pulp regeneration, with an emphasis on tissue engineering strategies.</p>
<p>In particular, tissue engineered scaffolds, which can provide a supportive structure for stem cell growth, will be examined. We discuss characteristics of an ideal scaffold, the use of growth factors which can have an important impact on cell proliferation and differentiation, and current therapies based on tissue engineering for dental pulp revitalization.</p>
</abstract>

Regenerative endodontics can be defined as a group of procedures that use tissue engineering, gene therapy, and stem cell-based approaches to regenerate tissue in tooth cavities. One of the main advantages of dental pulp revitalization compared to traditional endodontic treatments is that, by maintaining living tissue in the tooth cavity, teeth retain their defensive, nutritional, and sensory abilities which can provide protection against potential infection. This review discusses the application of stem cells in dental pulp regeneration, with an emphasis on tissue engineering strategies.
In particular, tissue engineered scaffolds, which can provide a supportive structure for stem cell growth, will be examined. We discuss characteristics of an ideal scaffold, the use of growth factors which can have an important impact on cell proliferation and differentiation, and current therapies based on tissue engineering for dental pulp revitalization.

Tissue engineering application in regenerative endodontics

Pomeranian Medical University in Szczecin

Department of Conservative Dentistry and Endodontics

Doctoral Studies of the Faculty of Dentistry, Department of Conservative Dentistry and Endodontics

Pomeranian Journal of Life Sciences

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Tissue engineering application in regenerative endodontics"}

Regenerative endodontics can be defined as a group of procedures that use tissue engineering, gene therapy, and stem cell-based approaches to regenerate tissue...

Tissue engineering application in regenerative endodontics

Publicado en línea: 24 jun 2021

Páginas: 10 - 17

DOI: https://doi.org/10.21164/pomjlifesci.718

Palabras clave
growth factors, regenerative endodontics, scaffold, stem cells, tissue engineering

© 2021 Alicja Nowicka et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Tissue engineering application in regenerative endodontics

Publicado en línea: 24 jun 2021

Páginas: 10 - 17

DOI: https://doi.org/10.21164/pomjlifesci.718

Palabras clavegrowth factors, regenerative endodontics, scaffold, stem cells, tissue engineering

© 2021 Alicja Nowicka et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Palabras clave
growth factors, regenerative endodontics, scaffold, stem cells, tissue engineering