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EUS in children with eosinophilic oesophagitis – a new method of measuring oesophageal total wall thickness area. An artificial intelligence application feasibility study. A pilot study

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08 nov 2024

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Fig. 1.

Oesophagus. Transverse section: lumen enclosed by oesophageal wall composed of mucosa, submucosa, muscular layer, and appendage. Histological specimen (animal; WMU museum collection). Courtesy of Prof. Piotr Dziegiel and dr. Aleksandra Piotrowska from the Department of Human Morphology and Embryology, Wroclaw Medical University
Oesophagus. Transverse section: lumen enclosed by oesophageal wall composed of mucosa, submucosa, muscular layer, and appendage. Histological specimen (animal; WMU museum collection). Courtesy of Prof. Piotr Dziegiel and dr. Aleksandra Piotrowska from the Department of Human Morphology and Embryology, Wroclaw Medical University

Fig. 2.

Oesophagus, EUS scan. Radial probe with balloon filled with water. 1. Mucosa, 2. Muscularis mucosae, 3. Submucosa, 4. Muscularis propria, 5. Adventitia. Courtesy of dr. Abdulhabib Annabhani from the Department and Clinic of Gastroenterology and Hepatology, Wroclaw Medical University
Oesophagus, EUS scan. Radial probe with balloon filled with water. 1. Mucosa, 2. Muscularis mucosae, 3. Submucosa, 4. Muscularis propria, 5. Adventitia. Courtesy of dr. Abdulhabib Annabhani from the Department and Clinic of Gastroenterology and Hepatology, Wroclaw Medical University

Fig. 3.

Oesophageal lumen and its wall in horizontal section (homocentric circles**). 1 (r) – radius of oesophageal L – 2 TWTa; Z – 1+2. * measuring points; ** two circles created homocentric (concentric or concentrical) circles with a common centre
Oesophageal lumen and its wall in horizontal section (homocentric circles**). 1 (r) – radius of oesophageal L – 2 TWTa; Z – 1+2. * measuring points; ** two circles created homocentric (concentric or concentrical) circles with a common centre

Fig. 4.

TWTa range in mm2 (minimal and maximal values) in children grouped according to weight
TWTa range in mm2 (minimal and maximal values) in children grouped according to weight

Square area of the oesophageal lumen with TWT (in mm2)

Children’s age (weight according to our experience) Square area of the oesophageal lumen with TWT (A = nr2; multiplication) in mm2
Oesophagus upper level Oesophagus lower level
0–3 years (3–18 kg) Calculations for 3 kg 3.14 and (3.5* + 4.2**)2= 186,17*** 3.14 and (4.4 + 4.2)2= 232.23
Calculations for 18 kg 3.14 and (4.55 + 4.2)2= 240.4 3.14 and (5.45 + 4.2)2= 292.4
Above 3–6 years (13–29 kg) Calculations for 13 kg 3.14 and (4.2 + 4.2)2= 221.56 3.14 and (5.1 + 4.2)2= 271.58
Calculations for 29 kg 3.14 and (5.35 + 4.2)2= 286.38 3.14 and (6.25 + 4.2)2= 342.89
Above 6–13 years (18–66 kg) Calculations for 18 kg 3.14 and (4.55 + 4.2)2= 240.41 3.14 and (5.45 + 4.2)2= 292.4
Calculations for 66 kg 3.14 and (7.9 + 4.2)2 = 459.73 3.14 and (8.9 + 4.2)2= 538.85
Above 13 years (39–70 kg) Calculations for 39 kg 3.14 and (6.05 + 4.2)2= 329.9 3.14 and (6.95 + 4.2)2= 390.37
Calculations for 70 kg 3.14 and (8.2 + 4.2)2 = 482.8 3.14 and (9.2 + 4.2)2= 563.82

TWTa calculated (mm2) at Th3-Th7 according to children’s age

Children’s age (weight) Square area of the TWT ring area (in mm2)
Oesophagus at the 3rd Th vertebral level Oesophagus at the 7th Th vertebral level
0–3 years (3–18 kg) Calculations for 3 kg 147.71* 171,44
Calculations for 18 kg 175.39 199.13
Above 3–6 years (13–29 kg) Calculations for 13 kg 166.17 189.91
Calculations for 29 kg 196.51 220.23
Above 6–13 years (18–66 kg) Calculations for 18 kg 175.39 199.13
Calculations for 66 kg 263.76 290.13
Above 13 years (39–70 kg) Calculations for 39 kg 214.97 238.7
Calculations for 70 kg 271.67 297.85

Square area of the oesophageal lumen calculated according the formula πr2 (in mm2)

Children’s age (weight according to our experience) Square area of the oesophageal lumen (A = πr2; multiplication) in mm2
Oesophagus at the 3rd Th vertebral level Oesophagus at the 7th Th vertebral level
0–3 years (3–18 kg) Calculations for 3 kg 3.14 and 3.5*2= 38.46 3.14 and 4.42= 60.79
Calculations for 18 kg 3.14 and 4.552= 65.01 3,14 and 5.452 = 93.27
Above 3–6 years (13–29 kg) Calculations for 13 kg 3.14 and 4.22 = 55.39 3.14 and 5.12= 81.67
Calculations for 29 kg 3.14 and 5.352 = 89.87 3.14 and 6.252= 122.66
Above 6–13 years (18–66 kg) Calculations for 18 kg 3.14 and 4.552= 65.01 3.14 and 5.452 = 93.27
Calculations for 66 kg 3.14 and 7.92= 195.97 3.14 and 8.92= 248.72
Above 13 years (39–70 kg) Calculations for 39 kg 3.14 and 6.052= 114.93 3.14 and 6.952= 151.67
Calculations for 70 kg 3.14 and 8.22= 211.13 3.14 and 9.22= 265.77
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Medicina, Ciencias médicas básicas, Ciencias médicas básicas, otros